Biostatistics

REVIEW QUESTIONS AND EXERCISES 397
Group
IA IB IIA IIB
12 Weeks
88 79 53 53
70 79 62 62
53 79 53 53
70 62 62 53
88 79
88 70
Source: Data provided courtesy of Dr. Howard Trachtman.
51. Twelve healthy men, ages 22 through 35 years, yielded the following serum T 3 ðnmol=LÞ levels at
0800 hours after 8 (day 1), 32 (day 2), and 56 (day 3) hours of fasting, respectively. Subjects were
participants in a study of fasting-induced alterations in pulsatile glycoprotein secretion conducted by
Samuels and Kramer (A-54).
Subject T 3 Day Subject T 3 Day Subject T 3 Day Subject T 3 Day
1 88 1 2 115 1 3 119 1 4 164 1
1 73 2 2 77 2 3 93 2 4 120 2
1 59 3 2 75 3 3 65 3 4 86 3
Subject T 3 Day Subject T 3 Day Subject T 3 Day Subject T 3 Day
5 93 1 6 119 1 7 152 1 8 121 1
5 91 2 6 57 2 7 70 2 8 107 2
5 113 3 6 44 3 7 74 3 8 133 3
Subject T 3 Day Subject T 3 Day Subject T 3 Day Subject T 3 Day
9 108 1 10 124 1 11 102 1 12 131 1
9 93 2 10 97 2 11 56 2 12 83 2
9 75 3 10 74 3 11 58 3 12 66 3
Source: Data provided courtesy of Dr. Mary H. Samuels.
52. To determine the nature and extent to which neurobehavioral changes occur in association with the
toxicity resulting from exposure to excess dietary iron (Fe), Sobotka et al. (A-55) used weanling male
Sprague-Dawley rats as experimental subjects. The researchers randomly assigned the animals,
according to ranked body weights, to one of five diet groups differentiated on the basis of amount
of Fe present: Control—35 (1), 350 (2), 3500 (3), 4 (iron deficient) (4), and 20,000 (5) ppm,
respectively. The following are the body weights of the animals (grams) at the end of 10 weeks.
Diet Weight Diet Weight Diet Weight
1 396 1 335 1 373
2 368 2 349 4 292
3 319 3 302 5 116
(Continued)