Biostatistics

290 CHAPTER 7 HYPOTHESIS TESTING
Normal Subjects
Pre-Exposure Post-Exposure
Subject FEV 1 Sraw FEV 1 Sraw
1 4.3 5.52 4.2 8.70
2 3.9 6.43 3.7 6.94
3 3.6 5.67 3.3 10.00
4 3.6 3.77 3.5 4.54
5 5.1 5.53 4.9 7.37 Source: Data provided courtesy
of Dr. Paul Blanc.
43. Noting the paucity ofinformation on the effect of estrogen on platelet membrane fatty acid composition,
Ranganath et al. (A-48) conducted a study to examine the possibility that changes may be present in
postmenopausal women and that these may be reversible with estrogen treatment. The 31 women
recruited for the study had not menstruated for at least 3 months or had symptoms of the menopause. No
woman was on any form of hormone replacement therapy (HRT) at the time she was recruited. The
following are the platelet membrane linoleic acid values before and after a period of HRT:
Subject Before After Subject Before After Subject Before After
1 6.06 5.34 12 7.65 5.55 23 5.04 4.74
2 6.68 6.11 13 4.57 4.25 24 7.89 7.48
3 5.22 5.79 14 5.97 5.66 25 7.98 6.24
4 5.79 5.97 15 6.07 5.66 26 6.35 5.66
5 6.26 5.93 16 6.32 5.97 27 4.85 4.26
6 6.41 6.73 17 6.12 6.52 28 6.94 5.15
7 4.23 4.39 18 6.05 5.70 29 6.54 5.30
8 4.61 4.20 19 6.31 3.58 30 4.83 5.58
9 6.79 5.97 20 4.44 4.52 31 4.71 4.10
10 6.16 6.00 21 5.51 4.93
11 6.41 5.35 22 8.48 8.80
Source: Data provided courtesy of Dr. L. Ranganath.
44. The purpose of a study by Goran et al. (A-49) was to examine the accuracy of some widely used bodycomposition
techniques for children through the use of the dual-energy X-ray absorptiometry (DXA)
technique. Subjects were children between the ages of 4 and 10 years. The following are fat mass
measurements taken on the children by three techniques—DXA, skinfold thickness (ST), and
bioelectrical resistance (BR):
DXA ST BR
Sex
(1 ¼ Male; 0 ¼ Female)
3.6483 4.5525 4.2636 1
2.9174 2.8234 6.0888 0
7.5302 3.8888 5.1175 0
6.2417 5.4915 8.0412 0
10.5891 10.4554 14.1576 0
9.5756 11.1779 12.4004 0
(Continued )