Biostatistics

284 CHAPTER 7 HYPOTHESIS TESTING
Id. No. Before After Id. No. Before After Id. No. Before After
1 195 125 37 221 191 73 205 151
2 208 164 38 245 164 74 298 163
3 254 152 39 250 162 75 305 171
4 226 144 40 266 180 76 262 129
5 290 212 41 240 161 77 320 191
6 239 171 42 218 168 78 271 167
7 216 164 43 278 200 79 195 158
8 286 200 44 185 139 80 345 192
9 243 190 45 280 207 81 223 117
10 217 130 46 278 200 82 220 114
11 245 170 47 223 134 83 279 181
12 257 182 48 205 133 84 252 167
13 199 153 49 285 161 85 246 158
14 277 204 50 314 203 86 304 190
15 249 174 51 235 152 87 292 177
16 197 160 52 248 198 88 276 148
17 279 205 53 291 193 89 250 169
18 226 159 54 231 158 90 236 185
19 262 170 55 208 148 91 256 172
20 231 180 56 263 203 92 269 188
21 234 161 57 205 156 93 235 172
22 170 139 58 230 161 94 184 151
23 242 159 59 250 150 95 253 156
24 186 114 60 209 181 96 352 219
25 223 134 61 269 186 97 266 186
26 220 166 62 261 164 98 321 206
27 277 170 63 255 164 99 233 173
28 235 136 64 275 195 100 224 109
29 216 134 65 239 169 101 274 109
30 197 138 66 298 177 102 222 136
31 253 181 67 265 217 103 194 131
32 209 147 68 220 191 104 293 228
33 245 164 69 196 129 105 262 211
34 217 159 70 177 142 106 306 192
35 187 139 71 211 138 107 239 174
36 265 171 72 244 166
Source: Data provided courtesy of William Tindall, Ph.D. and the Wright State University
Consulting Center.
20. The objective of a study by van Vollenhoven et al. (A-35) was to examine the effectiveness of
Etanercept alone and Etanercept in combination with methotrexate in the treatment of rheumatoid
arthritis. They performed a retrospective study using data from the STURE database, which
collects efficacy and safety data for all patients starting biological treatments at the major
hospitals in Stockholm, Sweden. The researchers identified 40 subjects who were prescribed
Etanercept only and 57 who were given Etanercept with methotrexate. One of the outcome
measures was the number of swollen joints. The following table gives the mean number of swollen
joints in the two groups as well as the standard error of the mean. Is there sufficient evidence at the