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Biostatistics

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436 CHAPTER 9 SIMPLE LINEAR REGRESSION AND CORRELATION<br />

Y<br />

Y<br />

Y<br />

X<br />

X<br />

X<br />

(a)<br />

(b)<br />

(c)<br />

FIGURE 9.4.6 Scatter diagrams showing (a) direct linear relationship, (b) inverse linear<br />

relationship, and (c) no linear relationship between X and Y.<br />

that there is an inverse linear relationship between X and Y. When there is no linear<br />

relationship between X and Y, ^b 1 is equal to zero. These three situations are illustrated in<br />

Figure 9.4.6.<br />

The Test Statistic<br />

known is<br />

For testing hypotheses about b 1 the test statistic when s 2 yjx is<br />

z ¼ ^b 1 ðb 1 Þ 0<br />

(9.4.8)<br />

s ^b 1<br />

where ðb 1 Þ 0<br />

is the hypothesized value of b 1 . The hypothesized value of b 1 does not have<br />

to be zero, but in practice, more often than not, the null hypothesis of interest is that<br />

b 1 ¼ 0.<br />

As a rule s 2 yjx<br />

is unknown. When this is the case, the test statistic is<br />

t ¼ ^b 1 ðb 1 Þ 0<br />

(9.4.9)<br />

s^b 1<br />

where s^b 1<br />

is an estimate of s ^b 1<br />

and t is distributed as Student’s t with n 2 degrees of<br />

freedom.<br />

If the probability of observing a value as extreme as the value of the test statistic<br />

computed by Equation 9.4.9 when the null hypothesis is true is less than a=2 (since we have<br />

a two-sided test), the null hypothesis is rejected.<br />

EXAMPLE 9.4.2<br />

Refer to Example 9.3.1. We wish to know if we can conclude that the slope of the<br />

population regression line describing the relationship between X and Y is zero.<br />

Solution:<br />

1. Data. See Example 9.3.1.<br />

2. Assumptions. We presume that the simple linear regression model and<br />

its underlying assumptions are applicable.

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