Biosafety Guidelines For Research On Genetically Modified ...

More documents

Recommendations

Info

From the Notifiable Diseases List of the Animal and Birds Act FAMILY GENUS SPECIES DISEASE Reoviridae Orbivirus AHS virus African horse sickness Reoviridae Orbivirus Bluetongue virus Bluetongue Reoviridae Orbivirus Eq encephalosis Equine encephalosis virus Retroviridae Lentivirus CAE virus Caprine arthritis/encephalitis Retroviridae Unclassified Bovine leukemia Enzootic bovine leucosis virus Retroviridae Lentivirus MD virus Maedi-visna Retroviridae (temp Equine infectious anaemia classification) Retrovirus unclassified Ovine pulmonary adenomatosis Rhabdoviridae Lyssavirus Rabies virus Rabies Rhabdovirus Lyssavirus Several species Lyssa encephalitis Rhabdovirus Vesiculovirus VSV Vesicular stomatitis Togaviridae Alphavirus VEE,WEE,EEE Equine encephalomyelitis Togaviridae Pestivirus EA virus Equine viral arteritis Togaviridae Alphavirus Getah virus Getah virus disease Unknown BSE agent Bovine spongiform encephalopathy Unknown TSE agent Transmissible spongiform encephalopathies Unknown Scrapie agent Scrapie Appendix - Page 53
APPENDIX 20: GLOSSARY Note: Words are defined in this Glossary according to the use they have in these <strong>Guidelines</strong> Agrobacterium tumefaciens amphotropic retrovirus amplify autoclave AVA bacterium bacteriophage baculovirus biological safety cabinet/biosafety cabinet cell characterised DNA chromosome clone conjugative plasmid construct A bacterium which infects plants and contains a plasmid (q.v.) that can be used to introduce foreign DNA into plant cells. A retrovirus (q.v.) that will grow in the cells from which it was isolated and also in cells from a wide range of other species. To increase the number of copies of a gene or DNA sequence A device in which materials are sterilised using steam under high pressure. Agri-food and Veterinary Authority of Singapore. A single-celled prokaryotic ( q.v.) organism. A virus that infects bacteria; also called phage. A group of viruses that infect insects and can be used as vectors (q.v.) to produce foreign proteins in insect cells. Specially constructed cabinets which are designed to protect workers and the environment from dangerous agents, especially bacteria and viruses. The smallest structural unit of living organisms that is able to grow and reproduce independently. DNA which has been sequenced and for which there is an understanding of the gene products. A structure in the cell, consisting of DNA and proteins, that carries the organism’s genes. As a noun: a group of genes, cells or organism derived from a common ancestor and genetically identical. As a verb: to generate replicas of DNA sequences or whole cells using genetic manipulation techniques. A plasmid ( q.v.) which codes for its own transfer between bacterial cells by the process of conjugation (‘mating’). As a noun: genetically manipulated DNA. Appendix - Page 54
Page 1 and 2:
THE SINGAPORE BIOSAFETY GUIDELINES
Page 3 and 4:
APPENDICES Appendix 1 Other Relevan
Page 5 and 6:
1.4 DEFINITIONS OF ABBREVIATIONS Fo
Page 7 and 8:
2.2 EXEMPTIONS 2.2.1 The following
Page 9 and 10:
SECTION 3: SUMMARY OF PROCEDURES 3.
Page 11 and 12:
3.3 CATEGORY A - EXPERIMENTS REQUIR
Page 13 and 14:
SECTION 4: EXPERIMENTS COVERED BY T
Page 15 and 16:
4.2 CATEGORY B - EXPERIMENTS REQUIR
Page 17 and 18:
SECTION 5: ROLES AND RESPONSIBILITI
Page 19 and 20:
5.2.5 Monitoring of Work The IBC sh
Page 21 and 22:
• submit a new proposal form to t
Page 23 and 24:
• All materials that are genetica
Page 25 and 26:
6.5 SUPPLY OF GENETICALLY MANIPULAT
Page 27 and 28:
6.6.5 The form should contain any r
Page 29 and 30:
BLANK PAGE
Page 31 and 32:
3. Worldwide guidelines specific to
Page 33 and 34:
xiv. AS 2252.2: 1994: xv. AS 2647:
Page 35 and 36:
APPENDIX 2: LIST OF GMAC-APPROVED H
Page 37 and 38:
APPENDIX 3: INSTRUCTIONS FOR COMPLE
Page 39 and 40: PROPOSAL FORM FOR ASSESSMENT OF GEN
Page 41 and 42: -----------------------------------
Page 43 and 44: ) Describe the techniques to be emp
Page 45 and 46: ii) Category B iii) Category C C. R
Page 47 and 48: APPENDIX 4: TOXINS For work involvi
Page 49 and 50: 4. Procedures for handling viruses
Page 51 and 52: staff shall handle these infected a
Page 53 and 54: APPENDIX 7: REQUIREMENTS FOR GENETI
Page 55 and 56: equire the provision of a front cov
Page 57 and 58: Signs 10. An automatically-starting
Page 59 and 60: 9. All plants in the plant house sh
Page 61 and 62: APPENDIX 12: PROCEDURES FOR EXPERIM
Page 63 and 64: APPENDIX 13: DESIGN OF ANIMAL FACIL
Page 65 and 66: Other Work Being Performed in the S
Page 67 and 68: permitted in animal rooms. Personne
Page 69 and 70: APPENDIX 15: REQUIREMENTS FOR GENET
Page 71 and 72: APPENDIX 16: REQUIREMENTS FOR INSEC
Page 73 and 74: APPENDIX 17: REQUIREMENTS FOR INSEC
Page 75 and 76: APPENDIX 18: PROCEDURES FOR EXPERIM
Page 77 and 78: From Bio-Security Assurance Arrange
Page 79 and 80: VIRUSES (con’t) Family and genus
Page 81 and 82: PESTS (cont’d) INSECTS MAIN HOST
Page 83 and 84: PESTS (cont’d) NEMATODES MAIN HOS
Page 85 and 86: PESTS (cont’d) NEMATODES MAIN HOS
Page 87 and 88: From the Notifiable Diseases List o
Page 89: From the Notifiable Diseases List o
Page 93 and 94: fusion gamete gene gene therapy gen
Page 95 and 96: polymerase chain reaction prion pro
show all

Biosafety Guidelines For Research On Genetically Modified ...

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?