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Biosafety Guidelines For Research On Genetically Modified ...

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APPENDIX 20: GLOSSARY<br />

Note: Words are defined in this Glossary according to the use they have in these<br />

<strong>Guidelines</strong><br />

Agrobacterium<br />

tumefaciens<br />

amphotropic retrovirus<br />

amplify<br />

autoclave<br />

AVA<br />

bacterium<br />

bacteriophage<br />

baculovirus<br />

biological safety<br />

cabinet/biosafety cabinet<br />

cell<br />

characterised DNA<br />

chromosome<br />

clone<br />

conjugative plasmid<br />

construct<br />

A bacterium which infects plants and contains a plasmid<br />

(q.v.) that can be used to introduce foreign DNA into plant<br />

cells.<br />

A retrovirus (q.v.) that will grow in the cells from which it<br />

was isolated and also in cells from a wide range of other<br />

species.<br />

To increase the number of copies of a gene or DNA<br />

sequence<br />

A device in which materials are sterilised using steam<br />

under high pressure.<br />

Agri-food and Veterinary Authority of Singapore.<br />

A single-celled prokaryotic ( q.v.) organism.<br />

A virus that infects bacteria; also called phage.<br />

A group of viruses that infect insects and can be used as<br />

vectors (q.v.) to produce foreign proteins in insect cells.<br />

Specially constructed cabinets which are designed to<br />

protect workers and the environment from dangerous<br />

agents, especially bacteria and viruses.<br />

The smallest structural unit of living organisms that is able<br />

to grow and reproduce independently.<br />

DNA which has been sequenced and for which there is an<br />

understanding of the gene products.<br />

A structure in the cell, consisting of DNA and proteins, that<br />

carries the organism’s genes.<br />

As a noun: a group of genes, cells or organism derived<br />

from a common ancestor and genetically identical. As a<br />

verb: to generate replicas of DNA sequences or whole<br />

cells using genetic manipulation techniques.<br />

A plasmid ( q.v.) which codes for its own transfer between<br />

bacterial cells by the process of conjugation (‘mating’).<br />

As a noun: genetically manipulated DNA.<br />

Appendix - Page 54

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