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The fact that 1,4-DHP lipid molecules moved from the initial bilayer structure to thetubular one and turned to micellaes suggests that the supramolecular structure of the 1,4-DHP lipid depend on external conditions, in high 1,4-DHP lipid concentrations veryprobably the gene transfection with 1,4-DHP lipid is performed by means of the tubularlipoplex in micellar hexagonal structure or complexed inverted hexagonal structure.Fig. 2. Binding of DNA between two tubomicelaes after 12676 ps of MD run.AcknowledgmentsThis work was supported by European Economic Area block grant "Academic Research"LV0015.EEZ09AP- 68, and by ESF project 2009/0197/1DP/1.1.1.2.0/09/APIA/VIAA/014.Calculations were performed on computers of the Gdansk Academic Computer Center TASK.References1. Tresset, G., Cheong, W.C.D., Tan, Y.L.S., Boulaire, J., Lam, Y.M. Biophysical Journal 93, 637-644(2007).2. Luo, D., Saltzman, M. Nature Biotechnology 18, 33-37 (2000).3. Belguise-Valladier, P., Behr, J.-P. Cytotechnology 35, 197-201, 2001.4. Liepina, I., Czaplewski, C., Ose, V., Danne, R., Duburs, G. Proceedings of NIC Workshop FromComputational Biophysics to System Biology, Julich, May 19-21, 2008, Germany., NIC, v40, (UlrichH.E. Hansman, Jan H., Meinke, Sandipan Mohanty, Walter Nadler, Olav Zimmermann, Eds), pp305-307.5. Hyvonen, Z., Plotniece, A., Reine, I., Chekavichus, B., Duburs, G., Urtti, A. Biochim. Biophys. Acta1509, 451-466 (2000).6. Hyvonen, Z., Ronkko, S., Toppinen, M.-R., Jaaskelainen, I., Plotniece, A., Urtti, A. Journal ofControlled Release 99, 177-190 (2004).631
Subject index(S)-2-(1-adamantyl)glycine 4321H-NMR spectroscopy 5762D IR spectroscopy 602, 6202D-NMR 292, 5423-(2-naphthyl)-L-alanine 3783C protease inhibitors 903D domain swapping 280, 2823-dipolar cycloaddition 303H labeling 5904-anilinoquinoline EGFR inhibitor 5624-DHP lipid 6304-dichloro-6-methoxy-1 1264-methylpseudoproline 4645-fluorouracil 3105-triazine 124, 1269-aminoacridine 230a4b1 integrin ligands 444ACE inhibitors 294, 346Ac-peptidyl-MCA 480activation of peritoneal macrophages 626activator 496acyclovir 528, 536adamantyltripeptides 484adjuvant 484, 550affibody 62, 180affinity chromatography 566AFGP 86aggregation 488Aib 616alamethicin analogues 372aldol 152alfa-Trifluoromethylated amino acids 72aliskiren 252alloferon 604Aloc group 112alpha-amino gamma-lactam 256alpha-MSH analog 530alpha-synuclein 332, 434Alzheimer's disease 178, 302, 594amine-azide 216amino acid synthesis 46amino acid toner 18aminoaldehydes 242aminophosphonates 486AMP 264amylin 570amyloid 40, 178, 304, 488amyloid beta protein 572amyloid fibrils 22amyloid formation 570, 572amyloidosis 570, 572analgesic activity 486analgesics 354analogues 438analogues of arginine vasopressin 432angiogenesis 444angiotensin 248angiotensin II 352, 546angiotensin IV 138angiotensin-converting enzyme inhibitor512anomer 550antagonist 248, 366, 460antagonist activity 246antamanide 328anthrose 88antibacterial peptide 146, 376anti-bactericidal mechanism 274antibiotics 152antibody detection 498anti-cancer activity 322, 576anti-cancer bradykinin 308anticorosion activity 70antidepressive action 334antifungal activity 406anti-HIV molecule 38antimicrobial 264antimicrobial activity 406antimicrobial compounds 260antimicrobial domains 418antimicrobial oligopeptide 412antimicrobial peptides 370, 378, 380,384, 388, 400, 404, 406, 414, 418, 564antioxidants 60antiproliferative activity 468antitumor 300antitumor activity 354, 522antiviral properties 90antivirals 336, 558Any-GS 604Apaf-1 552632
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Peptides 2010Tales of PeptidesProce
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Peptides 2010Tales of PeptidesProce
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IntroductionWe had the distinct hon
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Scientific programIn planning the 3
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31 st EUROPEAN PEPTIDE SYMPOSIUMSep
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published by John Wiley & Sons as a
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The Josef Rudinger AwardThis award
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Young Investigators' SymposiumThe y
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xxiv
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Design of Peptidyl-Inhibitors for G
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Synthetic Antifreeze Glycopeptide A
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Synthesis and Oxidative Folding of
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Convergent Syntheses of Huprp106-12
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Bactericidal Activity of Small Beta
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Bradykinin Analogues Acylated on Th
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Antimicrobial Activity of Small 3-(
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Interaction of Curcumin with A-Synu
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Fluorescent and Luminescent Fusion
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Cellular Expression of the Human An
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2D IR Spectroscopy of Oligopeptides
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large, non-redundant subset of prot
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The aberrantly glucosylated peptide
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Table 1. Proline cis/trans ratios o
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Table 1. Yields, UV-vis absorption
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Table 1. Purity of the targeted tri
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processes are blocked. Interestingl
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(tb4 n ,1 m )MTII(tb1 n ,4 m )MTIIF
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Fig. 2. a) Part of the 400 MHz HR-M
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Once printed, the amino acid partic
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A) PSA, few seconds73B) PSA, 45 min
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short β strands. In contrast, nume
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neg. control Cs9-Rhd MM-218Fig. 2.
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Table 1. The general structure of t
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% ID in the liver 1 h p.i.100908070
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Peptidyl phosphoranes were first re
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obtained from the same sardines and
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MccJ25 variants were produced by si
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Fig. 2. Proposed signaling mechanis
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Table 1. mCD4-HS12 antiviral activi
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Proceedings of the 31 st European P
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Page 627 and 628: Proceedings of the 31 st European P
Page 677: Proceedings of the 31 st European P
Page 681 and 682: chip 18chiral triazine condensing r
Page 683 and 684: heat stress 348helical conformation
Page 685 and 686: O-acyl isopeptide method 112obesity
Page 687 and 688: SH2-ligands 210short collagen-relat
Page 689 and 690: Author indexAboye, Teshome Leta 142
Page 691 and 692: Chi, Hongfang 480Chiche, Laurent 6C
Page 693 and 694: Geronikaki, Athina 444Gessmann, Ren
Page 695 and 696: Kostova, Kalina 528Kotzia, Georgia
Page 697 and 698: Nagata, Koji 162Nagayev, Igor Yu. 5
Page 699 and 700: Salvarese, Nicola 518Sammet, Benedi
Page 701 and 702: Vauquelin, Georges 138Veiga, Ana Sa
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