User Guide: ekspert™ nanoLC 400 Systems Operator ... - Eksigent

Regulatory and Safety InformationWARNING! Electrical Shock Hazard: Make sure that a protective earth(grounding) cable is connected between the injection valve's sample loop and anappropriate grounding point at the LC/MS source. This supplementary groundingwill reinforce the safety configuration specified by AB SCIEX.WARNING! Environmental Hazard: Follow a regulated, approved waste disposalprogram. Never dispose of flammable or toxic solvents into a municipal sewagesystem. Do not allow flammable or toxic solvents to accumulate.WARNING! Puncture Hazard: Do not operate the autosampler without the frontcover properly installed. To avoid injury during operation, keep hands and looseobjects away from the autosampler needle and syringe assembly.WARNING! Personal Injury Hazard: Use caution when working with any PEEKsil,fused silica or polymeric tubing under pressure:– Always wear proper eye protection when near the tubing.– Do not use tubing that has been severely stressed or kinked.– Do not use tubing, in particular PEEK or DuPont Tefzel tubing, withtetrahydrofuran (THF), dimethylsulfoxide (DMSO), chlorinated organic solvents,concentrated mineral acids, such as nitric, phosphoric or sulfuric acids, or anyrelated compounds.WARNING! Ocular Hazard: Do not look directly into the autosampler cabinetlamp. Possible eye injury due to hazardous optical radiation.Caution: Potential System Damage: Contact the manufacturer prior to making changesor modifications to the system. Changes or modifications to this unit not expresslyapproved by the manufacturer could void the instrument warranty and render the systeminoperable.Caution: Potential System Damage: Handle the system with care. Electrical damage mayhave occurred if any part of the system shows visible signs of damage, exposure toliquids or of having been transported under severe stress.Caution: Potential System Damage: Do not replace the on-board lithium battery. Thebattery maintains the autosampler firmware when the system is turned off. It should onlybe replaced by a factory-authorized service engineer.Caution: Potential System Damage: Do not store the system for prolonged periods underextreme conditions (for example, subjected to heat, water, etc.) as damage may occur.Caution: Potential Data Loss: Do not rely on analytical results from the system when achange is determined. When a change is observed in the retention of a particularcompound, the resolution between two compounds or peak shapes, immediatelydetermine the reason for the changes.Operator Guideekspert nanoLC 400 SystemsD5033460 C 11 of 174