493 Poster Developmental, Neurogenesis, and ConsumerResearchOXIDATIVE STRESS-MEDIATED DEGENERATIVECHANGES IN THE AGING MURINE OLFACTORY BULBVaishnav R.A. 1 , Barnett K.R. 2 , Poon H.F. 3 , Hunter S.A. 1 , Hahn Y.K. 1 ,Getchell M.L. 2 , Butterfield D.A. 3 , Getchell T.V. 1 1 Physiology,University of Kentucky, Lexington, KY; 2 Anatomy and Neurobiology,University of Kentucky, Lexington, KY; 3 Chemistry, University ofKentucky, Lexington, KYOur recent proteomic analysis of the aging olfactory systemdemonstrated changes in several oxidative stress proteins. Here, wehave investigated oxidative stress markers in olfactory bulbs (OB) ofold (20 months) vs. young (1.5 months) mice. Total proteincarbonylation was significantly higher in OBs of old mice. 2D gelelectrophoresis and Western blotting detected over 300 oxidizedproteins. Specific carbonylation levels of 4 proteins identified by massspectrometry-based redox proteomics significantly differed in old vs.young mice, demonstrating the selectivity of age-associated changes inprotein oxidation. Of these, aldolase 1, localized in astroglia in thegranule cell layer, showed a 13-fold increase in carbonyl levels withaging. The oxidative stress management protein ferritin heavy chain 1was also carbonylated; it was up-regulated and localized in mitral/tuftedcells. Endothelial cells and microglia in the glomerular layer wereimmunoreactive for 3-nitrotyrosine, an oxidative protein modification,in OBs of old mice. We initiated GeneChip analyses to study globalchanges in the oxidative stress response. Genes regulated in the agingOB include key antioxidant proteins, chaperones and apoptosis pathwaymembers. Our results provide fundamental insight into the role ofoxidative stress in the aging OB. Support: AG-16824 (TVG); AG-05119 & AG-10836 (DAB).494 Poster Developmental, Neurogenesis, and ConsumerResearchODOR INCREASES INFANTS´ ATTENTION TO DYNAMICEMOTION DISPLAYHaviland-Jones J. 1 , Coffield C. 1 , Mayhew E. 1 , Walker-Andrews A. 21 Psychology, Rutgers, The State University of New Jersey, Piscataway,NJ; 2 Psychology, Montana State University, Missoula, MTInfants show specific preferences when it comes to looking atemotional expressions. Infants look longer at happy than sadexpressions (Walker-Andrews, 1977). Infants look longer to dynamicdisplays of emotion (Caron et al, 1988) and longer when displays havesound (Walker 1982). How might another sensory input (odor) affectinfants´ looking time? Thirty infants were shown both happy and saddynamic expressions (counterbalanced) in one of three conditions: noodor, pine or baby powder. Infants looked longer when they were in theodor conditions, regardless of the emotion displayed (p < 0.049). Thissuggests that the addition of the odor sensory channel increasesalertness and enables an infant to maintain visual attention, even tostimuli usually avoided (e.g., sad emotion expression).495 Poster Developmental, Neurogenesis, and ConsumerResearchEFFECTS OF AROMA ON AMATEUR TEN-PIN BOWLINGPERFORMANCEHirsch A.R. 1 , Ye Y. 2 , Lu Y. 3 , Choe M. 3 1 The Smell & Taste Treatmentand Research Foundation, Chicago, IL; 2 University of Illinois atChicago, Chicago, IL; 3 Illinois Mathematics and Science Academy,Aurora, ILIntroduction: While odor has been noted to have an impact in somesports, effects on bowling have never been addressed. Methods:Twenty subjects in a single-blind fashion bowled two frames. Oneframe was while wearing a blank surgical mask and the other was whilewearing a mask impregnated with the aroma of jasmine. These werepresented in a counterbalanced order. On an analog scale, subjects ratedthe hedonics of the jasmine aroma.Results: With the blank mask, theaverage score was 6.00, whereas while bowling with the jasmineimpregnated mask the average score was 8.35 (p = 0.0053). No effecton bowling score was seen in relation to absolute hedonics (p = 0.29),or relative hedonics—like/dislike (p = 0.64), of the jasminearoma.Conclusions: Ten-pin bowling in the presence of the odor ofjasmine improved scores. Possible mechanisms of action include moodregulation, enhanced alertness or concentration, anxiolysis, increasedself-confidence, and improved hand-eye coordination. A similar effectof jasmine may be observed in other sports requiring precise hand-eyecoordination or precision in execution.496 Poster Developmental, Neurogenesis, and ConsumerResearchFLORAL ODOR PROMPTS POSITIVE EMOTIONALSEARCHESWilson P. 1 , Coffield C. 2 , Haviland-Jones J. 2 1 Psychology, La SalleUniversity, Philadelphia, PA; 2 Psychology, Rutgers, The StateUniversity of New Jersey, Piscataway, NJFlowers preferred by humans increase Duchenne smiling and socialbehavior and decrease negative mood reports. Would a floral odor alsoaffect emotional behavior? 123 participants (66 female) rated their ownemotional state, rated the emotional response to short fear/anger videosand reported a recent memory in either a gardenia, peppermint or Etohcondition. There is no effect of odor on ratings of pleasantness orintensity (both odors are different from Etoh only).Condition did noteffect self-rating of mood. There is an effect of emotional response tothe fear/anger videos for positive emotion (p < 0.002) and negativeemotion (p < 0.02); both gardenia and peppermint prompt higherpositive emotion than Etoh but peppermint also prompts more negativeemotion than Etoh. There is an effect of odor on social reference wordsin the memory narrative (p < 0.02); gardenia prompts more than EtohThese results support the hypothesis that floral odor specializes insearches for positive emotion and social reference.124
497 Poster Developmental, Neurogenesis, and ConsumerResearchBEAUTY IS IN THE “NOSE” OF THE BEHOLDER—UNCONSCIOUS SMELLS INFLUENCE PERCEIVEDLIKABILITYLi W. 1 , Moallem I. 1 , Paller K.A. 1 , Gottfried J. 1 1 NorthwesternUniversity, Chicago, ILThe direct projections between the olfactory bulb and the limbicsystem suggest that olfactory input may induce emotion withoutneocortical involvement, and perhaps independently of consciousawareness of smell. We used sub-threshold concentrations of pleasant(citric acid), unpleasant (valeric acid) and neutral (anisole) odorants totest whether the emotional content of smells could be accessedsubliminally so as to influence affective judgments. In each subject,detection thresholds were determined for each odorant by requiring fiveconsecutive hits in a two-alternative forced-choice ascending staircaseprocedure (using 1/3 serial dilutions). We then presented odorants 3dilution steps below threshold for presence/absence judgments. In eachof 80 trials, the subject sniffed from a bottle containing one of theodorants or mineral oil alone. After sniffing the subject saw a photo of aneutral face (80 different faces) and rated how much they liked thatperson. Performance on the odor-detection task was at chance level in22 out of 39 subjects. These subjects thus demonstrated lack ofconscious awareness of odors. Also, they showed a shift in likabilityjudgments towards the valence of the preceding odor; faces preceded byunpleasant odor were rated less likable than faces following pleasant orneutral odors. These data provide clear evidence that emotionalproperties of a subliminal odor can be processed so as to influence one´semotional reaction to another person. Furthermore, these findings implythat unconscious smells can potentially influence everyday behavior.Funding sources: Northwestern Univ.; NSF.499 Poster Developmental, Neurogenesis, and ConsumerResearchCOGNITIONS INFLUENCE COLOR-ODORCORRESPONDENCESAbreu D. 1 , Mattern-Mcclory R. 1 , McGarry A. 1 , Zellner D. 11 Psychology, Montclair State University, Montclair, NJIt has been demonstrated previously that certain colors are selected ascorresponding to certain odors (e.g., Gilbert, Martin, & Kemp, 1996).We further investigate this effect using complex scents (the unisexfragrances CKOne and CKbe). In addition, we examine the influence oftelling subjects that the scents are male or female fragrances. Subjects(n = 68) smelled both CKOne and CKbe from identical sniff-bottles.Half of the subjects were told that the scents were female fragrances andthe other half were told that they were male. They were asked to assignfive “appropriateness” points to the following 11 colors: red, orange,yellow, green, blue, purple, pink, brown, white, grey, and black. For thetwo scents, both when subjects were told that they were male and whenthey were told that they were female fragrances, the points were notuniformly distributed among the 11 colors. Some colors were chosenmore frequently than were others [Friedman chi-square (10) = 21.25 to31.07, p < 0.02 in all cases]. In addition, the pattern of color selectiondepended on whether subjects were told that it was a male or femalescent [chi-square (10) = 52.31, p < 0.01 for CKOne and chi-square(10)= 44.75, p < 0.01 for CKbe]. Subjects who were told that the CKOnewas a female scent predominately chose pink whereas those who weretold that it was a male scent chose blue. Subjects who were told thatCKbe was a female scent predominately chose yellow whereas subjectsshow were told that it was a male scent chose blue. While the actualodor of a scent plays some role in odor-color correspondences, how asubject thinks of the odor may play an even more important role.498 Poster Developmental, Neurogenesis, and ConsumerResearchEFFECTS OF PLEASANT AND UNPLEASANT ODORS ONEXERCISE PERFORMANCETimothy A.A. 1 , Hornung D.E. 1 1 St. Lawrence University, Canton, NYThis study evaluated the effect of the smell of lavender (pleasant),butyric acid (unpleasant), and octane (unpleasant) on the exerciseperformance of female college students. During a test session, subjectswere instructed to peddle as fast as they could for 20 minutes on astationary bike. During a session, subjects were exposed to the smell oflavender, octane, butyric acid or to an odorless control. The subject´sheart rate, speed, and distance traveled were recorded every 2 minutes.Each experimental condition (lavender, octane, butyric acid andodorless control) was repeated 3 times for a total of 12 trials per subject.As expected, exposure to lavender improved exercise performancecompared to the performance seen with the water control. Althoughexposure to unpleasant smell of octane also increased performance, thesmell of butyric acid did not alter performance. The increase inperformance seen with lavender was accompanied by a decreased heartrate for at least part of the exercise period whereas the increasedperformance seen with octane as accompanied by an increase in heartrate. Perhaps pleasant odors like lavender facilitate entering the“zone”—a relaxed state in which actions are more reflexive andattention is focused in a good way on the task at hand. On the otherhand the increased performance seen with unpleasant odors like octanemay be related more to their irritating psychological properties.500 Poster Developmental, Neurogenesis, and ConsumerResearchMEASURING ODOR ATTITUDES IN AN IMPLICIT WAYBulsing P. 1 , Smeets M. 1 , Van Den Hout M. 1 1 University of Utrecht,Utrecht, NetherlandsIntroduction: Beliefs and attitudes about odors and exposure effectscan influence odor perception in an implicit way. So far, researchershave tried to map these odor attitudes by using self-reportmeasurements, and thus by asking people to think explicitly about theirattitudes. Objective: To measure odor attitudes in an implicit way, wedeveloped an odor version of the Implicit Association Test (IAT;Greenwald et al., 1998) Validation of this odor-IAT will be discussed.Methods: Three experiments were conducted to test the odor-IAT,which is a computerized reaction time task, during which participantshave to associate words from the concept “odor” with positive andnegative words, by pressing the corresponding keys on a computerkeyboard. Participants, not selected on specific odor attitudes(Experiment 1 and Replication Experiment 2) and participants whofrequently use aromatherapy products (Experiment 3) completed thetest. They were all psychology students. Implicit odor attitudes wereinferred from examining response latencies and error rates. Results: Ingeneral, lower response latencies and error rates were observed duringphases of the test where “odor” had to be associated with positivewords, reflecting an overall positive attitude towards odors inExperiment 1 and 2. This odor attitude was even more positive withinan aromatherapy group in Experiment 3 compared to participants whoreported they never use aromatherapy products. The odor-IAT wascapable of making distinctions between various implicit odor attitudes.Participants with a negative attitude towards odors are currently beingtested. Funded by NWO 452-03-334.125
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