LATVIA UNIVERSITY OF AGRICULTURE - Latvijas ...

DYNAMIC MODEL OF BIOCHEMICAL NETWORK OF ZYMOMONASMOBILIS ADAPTATION FOR GLYCEROL CONVERSION INTO BIOETHANOLIlona OdzinaResults from time course plots:Plot 1 ‘Concentrations, Volumes, and GlobalQuantity Values’ (Fig. 1); (x axis – s (second), y axis -µmol s -1 ). In this model accumulate product GAP andGLUC6P. This problem in model is currently beingaddressed with parameter estimation methods, butin this moment are not good results. Other productachieves stability after two thousand seconds. Otherspecies has low flow. The model aims to produceethanol from glycerol and here you can see that theethanol is produced, but not sufficiently and modelstill needs to improve.Plot 2 ‘Reactions fluxes’ (Fig. 2) (x axis – s(second), y axis - µmol s -1 ). All reaction fluxes achievestability flux after two thousand seconds.800 000700 000600 000GAP500 000µmol s -1400 000300 000200 000GLUC6P100 000ETHOHout00 2000 4000 6000 8000 10000sFigure 1. Concentrations, Volumes, and Global Quantity Values.0.0060.0040.002µmol s -1µmol s -10-0.002-0.0040 500 1000 1500 2000 2500 3000 3500 4000sFigure 2. Reaction fluxes.236 Research for Rural Development 2012