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Recovery From Schizophrenia: Psychiatry And Political Economy

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18 BACKGROUNDFigure 1.2 Interactional model for factors possibly affecting the onset, course and outcomeof schizophreniaplay important roles before schizophrenia becomes manifest. Nearly two-thirds ofpeople with schizophrenia, moreover, have no relative at all with the illness. 34 If agenetic vulnerability is always present in schizophrenia it must skip generations;the interaction of more than one gene and environmental factors may benecessary for the illness to become apparent.Studies of twins reveal additional information about the inheritance ofvulnerability to schizophrenia. 35 When one of a pair of identical twins has asevere and deteriorating form of schizophrenia, it is virtually certain that the othertwin will show signs of the illness; but if one identical twin has a mild form of the

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