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on laboratory measurements, and thus their impact on the<br />

evaluation of data over time. Crossover studies have been<br />

conducted to evaluate the impact of laboratory changes on<br />

both FPG and A1c. The recommended adjustments to FPG to<br />

account for laboratory changes from 2005–2006 to present<br />

have been incorporated in estimates presented in Health,<br />

United States so that these estimates are compatible with<br />

those from earlier years. NHANES does not recommend any<br />

adjustments to the A1c data.<br />

Estimates presented in Health, United States may differ from<br />

other estimates based on the same data and presented<br />

elsewhere if different weights, age-adjustment groups,<br />

definitions, or trend adjustments are used.<br />

For more information, see: http://wwwn.cdc.gov/nchs/<br />

nhanes/2011-2012/GHB_G.htm and http://wwwn.cdc.gov/<br />

nchs/nhanes/2011-2012/GLU_G.htm.<br />

Diagnosis—Diagnosis is the act or process of identifying or<br />

determining the nature and cause of a disease or injury<br />

through evaluation of patient history, examination, and<br />

review of laboratory data. Diagnoses in the National Hospital<br />

Discharge Survey, the National Ambulatory Medical Care<br />

Survey, and the National Hospital Ambulatory Medical Care<br />

Survey are abstracted from medical records and coded to<br />

the International Classification of Diseases, 9th Revision,<br />

Clinical Modification (ICD–9–CM).<br />

For a given medical care encounter, the first-listed diagnosis<br />

can be used to categorize the visit, or if more than one<br />

diagnosis is recorded on the medical record, the visit can be<br />

categorized based on all diagnoses recorded. Analyzing<br />

first-listed diagnoses avoids double-counting events such as<br />

visits or hospitalizations; the first-listed diagnosis is often,<br />

but not always, considered the most important or dominant<br />

condition among all comorbid conditions. However, the<br />

choice of the first-listed diagnosis by the medical facility may<br />

be influenced by reimbursement or other factors. A hospital<br />

discharge would be considered a first-listed stroke discharge<br />

if the diagnosis code for stroke was recorded in the first<br />

diagnosis field on the hospital record. An any-listed stroke<br />

discharge would classify all diagnoses of stroke recorded on<br />

the hospital face sheet, regardless of the order in which they<br />

are listed. Any-listed diagnoses double-count events such as<br />

visits or hospitalizations with more than one recorded<br />

diagnosis but provide information on the burden a specific<br />

diagnosis presents to the health care system. (Also see<br />

Appendix II, External cause of injury; Injury; Injury-related<br />

visit.)<br />

Diagnostic and other nonsurgical procedure—See<br />

Appendix II, Procedure.<br />

Discharge—The National Health Interview Survey defines a<br />

hospital discharge as the completion of any continuous<br />

period of stay of one night or more in a hospital as an<br />

inpatient. According to the National Hospital Discharge<br />

Survey and the Healthcare Cost and Utilization<br />

Project—National (Nationwide) Inpatient Sample, a<br />

discharge is a completed inpatient hospitalization. A<br />

hospitalization may be completed by death or by release of<br />

the patient to the customary place of residence, a nursing<br />

home, another hospital, or other locations. (Also see<br />

Appendix II, Admission; Average length of stay; Days of care;<br />

Hospital utilization; Inpatient.)<br />

Domiciliary care home—See Appendix II, Long-term care<br />

facility; Nursing home.<br />

Drug—Drugs are pharmaceutical agents, by any route of<br />

administration, for the prevention, diagnosis, or treatment of<br />

medical conditions or diseases. Data on specific drug use are<br />

collected in several NCHS surveys. (Also see Appendix II,<br />

Multum Lexicon Plus therapeutic class.)<br />

National Health and Nutrition Examination Survey<br />

(NHANES)—Drug information from NHANES III and from<br />

NHANES for 1999 and subsequent years was collected<br />

during in-person interviews conducted in participants'<br />

homes. Starting with 2001 data, participants were asked<br />

whether they had taken a medication in the past 30 days<br />

for which they needed a prescription. For 1999–2000 and<br />

1988–1994 data, the question wording differed slightly;<br />

participants were asked whether they had taken a<br />

prescription medication in the past month. For all survey<br />

years, those who answered ‘‘yes’’ were asked to provide<br />

the prescription medication containers for the<br />

interviewer. For each medication reported, the<br />

interviewer entered the product's complete name from<br />

the container. If no container was available, the<br />

interviewer asked the participant to verbally report the<br />

name of the medication. In addition, participants were<br />

asked how long they had been taking the medication<br />

and the main reason for use.<br />

All reported medication names were converted to their<br />

standard generic ingredient name. For multi-ingredient<br />

products, the ingredients were listed in alphabetical<br />

order and counted as one drug (e.g., Tylenol #3 was listed<br />

as acetaminophen; codeine). No trade or proprietary<br />

names were provided on the data file.<br />

Drug data from NHANES provide a snapshot of all<br />

prescribed drugs reported by a sample of the civilian<br />

noninstitutionalized population for a 30-day period (or<br />

past month, for earlier survey years). Drugs taken on an<br />

irregular basis, such as every other day, once per week, or<br />

for a 10-day period, were captured in the 30-day recall<br />

period. Data shown in Health, United States for the<br />

percentage of the population reporting multiple<br />

prescription drugs during the past 30 days include a<br />

range of drug utilization patterns; for example, persons<br />

who took three or more drugs daily during the past 30<br />

days or persons who took a different drug three separate<br />

times would be classified as taking three or more drugs<br />

in the past 30 days, as long as at least three different<br />

drugs were taken at some time during the past 30 days.<br />

408 Appendix II. Definitions and Methods Health, United States, 2014

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