03.03.2017 Views

On the Spectrum

2lm5UyR

2lm5UyR

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

excluding children scoring highest on <strong>the</strong> SRS.<br />

Chapter 5<br />

Figure Legends:<br />

Figure 1. Graphical depiction of <strong>the</strong> analysis method and key findings.<br />

(A) The static and dynamic functional network connectivity (FNC) approach begin with group independent<br />

component analysis (ICA) to decompose resting-state fMRI data into intrinsic connectivity networks<br />

Figure (ICNs). The 1. Graphical group ICA approach depiction provides of <strong>the</strong> analysis a measure method of <strong>the</strong> and component key findings. time courses (A) The (TC) static and and spatial<br />

maps for each subject using <strong>the</strong> back-reconstruction technique. (B) Static FNC between components is<br />

dynamic estimated functional as <strong>the</strong> covariance network of <strong>the</strong> connectivity time courses. (FNC) (C) Dynamic approach FNC begin is estimated with group as <strong>the</strong> independent<br />

covariance from<br />

windowed portions of <strong>the</strong> time courses. (D) K-means clustering is used to identify discrete dynamic<br />

connectivity states. (E) Results obtained from k-means clustering are used to determine which state<br />

27<br />

a<br />

given subject is occupying at a given time, and summary measures of dynamic states, such as, mean<br />

dwell time (MDT) and fraction of time (FT) spent in each state over <strong>the</strong> duration of <strong>the</strong> measurement<br />

period are computed. (F) Highlights of <strong>the</strong> key findings for pairwise network analyses and summary<br />

measures analyses in association with age, sex and autistic traits.<br />

102

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!