On the Spectrum

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Cortical morphology in children with autistic traits and white matter surfaces against an additional surface that tightly wraps the pial surface are used to estimate the degree of cortical folding at a 25 mm spherical vertex-based region. This method has been validated and used in several studies focusing on childhood and adolescent psychopathology (13, 14). The surface based LGI maps were smoothed prior to the analyses using a 5 mm full-width half-maximum (FWHM) Gaussian kernel, consistent with several comparable studies (13). 2 SUPPLEMENTARY REFERENCES 1. Allochtonen in Nederland. Voorburg/Heerlen: Amsterdam University Press; 2004. 2. Oldfield RC. The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia. 1971;9(1):97-113. 3. Netherlands S. Standaardonderwijsindeling. Voorburg/Heerlen2004. 4. Grzadzinski R, Di Martino A, Brady E, Mairena MA, O’Neale M, Petkova E, Lord C, Castellanos FX. Examining autistic traits in children with ADHD: does the autism spectrum extend to ADHD? J Autism Dev Disord. 2011;41(9):1178-91. 5. Tellegen PJ W-WB, Laros JA. Snijders-Oomen Niet-Verbale Intelligentietest: SON-R 2.5 - 7/. Amsterdam: Boom Testuitgevers; 2005. 6. Constantino JN. Social Responsiveness Scale (SRS), Manual. Los Angeles: Western Psychological services; 2002. 7. Charman T, Baird G, Simonoff E, Loucas T, Chandler S, Meldrum D, Pickles A. Efficacy of three screening instruments in the identification of autistic-spectrum disorders. Brit J Psychiat. 2007;191:554-9. 8. Roeyers H TM, Druart C, De Schryver, M, & Schittekate, M. SRS Screeningslijst voor autismespectrumstoornissen. Handleiding Amsterdam: Hogrefe; 2011. 9. Dale AM, Fischl B, Sereno MI. Cortical surface-based analysis - I. Segmentation and surface reconstruction. Neuroimage. 1999;9(2):179-94. 10. Fischl B, Dale AM. Measuring the thickness of the human cerebral cortex from magnetic resonance images. P Natl Acad Sci USA. 2000;97(20):11050-5. 11. Ghosh SS, Kakunoori S, Augustinack J, Nieto-Castanon A, Kovelman I, Gaab N, Christodoulou JA, Triantafyllou C, Gabrieli JD, Fischl B. Evaluating the validity of volume-based and surface-based brain image registration for developmental cognitive neuroscience studies in children 4 to 11 years of age. Neuroimage. 2010;53(1):85-93. 12. Schaer M, Ottet MC, Scariati E, Dukes D, Franchini M, Eliez S, Glaser B. Decreased frontal gyrification correlates with altered connectivity in children with autism. Frontiers in Human Neuroscience. 2013;7. 13. Wallace GL, Robustelli B, Dankner N, Kenworthy L, Giedd JN, Martin A. Increased gyrification, but comparable surface area in adolescents with autism spectrum disorders. Brain. 2013;136:1956-67. 14. Kelly PA, Viding E, Wallace GL, Schaer M, De Brito SA, Robustelli B, McCrory EJ. Cortical Thickness, Surface Area, and Gyrification Abnormalities in Children Exposed to Maltreatment: Neural Markers of Vulnerability? Biol Psychiat. 2013;74(11):845-52. 45
Chapter 2 Supplementary Figure 1. Flowchart Imaging datalock August 2013 N=1070 SRS missing N=214 SRS available N=856 Insufficient quality 105 Incidental finding: 2 Gyrification output not constructed: 15 Sufficient quality scans and output N=734 Siblings/twins N=17 Final sample N=717 46
Page 1 and 2: On the Spectrum the neurobiology of
Page 3 and 4: ISBN: 978-94-6233-336-9 © Laura Bl
Page 5 and 6: PROMOTIECOMMISSIE Promotoren Overig
Page 8: MANUSCRIPTS THAT FORM THE BASIS OF
Page 11 and 12: Chapter 1 10
Page 13 and 14: Chapter 1 Cuthbert, Garvey, Heinsse
Page 15 and 16: Chapter 1 folding of the brain into
Page 17 and 18: Chapter 1 beneficial for treatment
Page 19 and 20: Chapter 1 REFERENCES Achenbach, T.
Page 21 and 22: Chapter 1 Sonuga-Barke, E. J. S.
Page 24: IPart I: The neurobiology of autist
Page 27 and 28: Chapter 2 ABSTRACT Objective: Recen
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Page 33 and 34: Chapter 2 Gyrification Six regions
Page 35 and 36: Chapter 2 The association remained
Page 37 and 38: Chapter 2 Table 4. Autistic traits
Page 39 and 40: Chapter 2 While we found widespread
Page 41 and 42: Chapter 2 REFERENCES Amaral, D. G.,
Page 43 and 44: Chapter 2 Wallace, G. L., P. Shaw,
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5 From Chronnectivity To Chronnecto
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From Chronnectivity To Chronnectopa
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nalysis did not reveal any FDR-corr
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6 Cognitive functioning in children
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Cognitive functioning in children w
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Chapter 7 ABSTRACT Objectives: In c
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Chapter 7 profile analysis performe
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Chapter 7 have been demonstrated pr
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Chapter 7 Next, we examined associa
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Chapter 7 Table 2 Brain morphology
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Chapter 7 Table 3 Cortical thicknes
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Chapter 7 Our finding was suggestiv
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Chapter 7 Using empirically defined
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Chapter 7 Fischl, B. and A. M. Dale
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Chapter 7 Supplement Table 1 Brain
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IIIPart III
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Chapter 8 190
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Chapter 8 stable relationships, and
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Chapter 8 gyrification changes in p
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Chapter 8 genetic or environmental
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Chapter 8 diseases, according to th
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Chapter 8 ability may be even more
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Chapter 8 symptoms could be more sp
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Chapter 8 association of maternal v
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Chapter 8 REFERENCES Abrahams, B. S
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Chapter 8 Goddard, M. N., S. van Ri
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Chapter 8 Sebat, J., B. Lakshmi, D.
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SSummary Samenvatting
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Summary SUMMARY Despite evidence fr
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Summary along a continuum were used
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Samenvatting SAMENVATTING Genetisch
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Samenvatting jonge kinderen die zic
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Addendum Mous SE, Schoemaker NK, Bl
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Addendum Zoeken in andere databases
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Addendum School of Women’s and In
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Addendum Graag wil ik Dr. Marion Sm
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Addendum hebben. Dank in het bijzon
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On the Spectrum

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