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Gene Variant Report issued

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Lifestyle Genomics Research Centre Ltd.<br />

Plymouth Science Park, 1 Davy Road, Derriford, Plymouth, PL6 8BX , UNITED KINGDOM<br />

contact us<br />

SAMPLE PROCESSED BY:<br />

METHOD:<br />

DATA CHECKED FOR ACCURACY BY:<br />

Genome Centre at BARTS and The London School of Medicine and Dentistry<br />

Fluidigm TaqMan probe-based SNP genotyping / Illumina MiSeq, Next <strong>Gene</strong>ration<br />

sequencing<br />

Genome Centre at BARTS and The London School of Medicine and Dentistry<br />

NOTES:<br />

genotype has no risk alleles<br />

genotype has one risk allele<br />

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genotype has two risk allels<br />

either allele can be a risk or be<br />

beneficial<br />

Ctr+F to activate Search Engine: Look up genes, rsids, pathways / traits<br />

SNP RSID INTERPRET ☞ PARENT GENE & VARIANT ⚛ CATEGORY ☤ / PATHWAY ⥹ RISK ALLELES !! cp00035774<br />

rs4846914<br />

The A (minor) allele is associated<br />

with increased levels of HDL<br />

cholesterol (good cholesterol) but<br />

GALNT2 Diet & Nutrition / Cholesterol Status GG GA<br />

also is associated with higher risk of<br />

hypertriglyceridemia.<br />

rs1800961 rs1800961 HNF4A Diet & Nutrition / Cholesterol Status TT CC<br />

rs1884614 rs1884614 HNF4A Diet & Nutrition / Cholesterol Status TT CC<br />

rs17700633<br />

The Minor "A" allele is associated<br />

with decreased HDL cholesterol .<br />

The G (major) allele is associated<br />

with increased HDL cholesterol.<br />

MC4R Diet & Nutrition / Cholesterol Status AA GA<br />

rs2229616<br />

The C (major) allele is associated<br />

with decreased HDL cholesterol<br />

levels.<br />

MC4R Diet & Nutrition / Cholesterol Status CC CC

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