18.02.2019 Views

Gene Variant Report issued

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Lifestyle Genomics Research Centre Ltd.<br />

Plymouth Science Park, 1 Davy Road, Derriford, Plymouth, PL6 8BX , UNITED KINGDOM contact us<br />

SAMPLE PROCESSED BY:<br />

METHOD:<br />

DATA CHECKED FOR ACCURACY BY:<br />

Genome Centre at BARTS and The London School of Medicine and Dentistry<br />

Fluidigm TaqMan probe-based SNP genotyping / Illumina MiSeq, Next <strong>Gene</strong>ration<br />

sequencing<br />

Genome Centre at BARTS and The London School of Medicine and Dentistry<br />

NOTES:<br />

genotype has no risk alleles<br />

genotype has one risk allele<br />

READ THIS FIRST JOIN US ON FACEBOOK BOOK AN APPOINTMENT<br />

genotype has two risk allels<br />

either allele can be a risk or be<br />

beneficial<br />

Ctr+F to activate Search Engine: Look up genes, rsids, pathways / traits<br />

SNP RSID INTERPRET ☞ PARENT GENE & VARIANT ⚛ CATEGORY ☤ / PATHWAY ⥹ RISK ALLELES !! cp00035774<br />

rs12273363<br />

rs6265<br />

Neurotrophins are chemicals that<br />

help to stimulate and control<br />

neurogenesis, BDNF being one of<br />

the most active. The C allele is<br />

associated with more with mood<br />

disorders than T.The minor C allele<br />

might increased activity in the<br />

amygdala (a region in brain). This<br />

might increase anxiety and<br />

emotional memory.<br />

Neurotrophins are chemicals that<br />

help to stimulate and control<br />

neurogenesis, BDNF being one of<br />

the most active. “T” allele carriers<br />

had lower blood BDNF than CC<br />

BDNF <strong>Gene</strong>ral Health / Cognitive CC TT<br />

BDNF <strong>Gene</strong>ral Health / Cognitive TT CT

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