Gene Variant Report issued
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Lifestyle Genomics Research Centre Ltd.<br />
Plymouth Science Park, 1 Davy Road, Derriford, Plymouth, PL6 8BX , UNITED KINGDOM contact us<br />
SAMPLE PROCESSED BY:<br />
METHOD:<br />
DATA CHECKED FOR ACCURACY BY:<br />
Genome Centre at BARTS and The London School of Medicine and Dentistry<br />
Fluidigm TaqMan probe-based SNP genotyping / Illumina MiSeq, Next <strong>Gene</strong>ration<br />
sequencing<br />
Genome Centre at BARTS and The London School of Medicine and Dentistry<br />
NOTES:<br />
genotype has no risk alleles<br />
genotype has one risk allele<br />
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genotype has two risk allels<br />
either allele can be a risk or be<br />
beneficial<br />
Ctr+F to activate Search Engine: Look up genes, rsids, pathways / traits<br />
SNP RSID INTERPRET ☞ PARENT GENE & VARIANT ⚛ CATEGORY ☤ / PATHWAY ⥹ RISK ALLELES !! cp00035774<br />
rs12273363<br />
rs6265<br />
Neurotrophins are chemicals that<br />
help to stimulate and control<br />
neurogenesis, BDNF being one of<br />
the most active. The C allele is<br />
associated with more with mood<br />
disorders than T.The minor C allele<br />
might increased activity in the<br />
amygdala (a region in brain). This<br />
might increase anxiety and<br />
emotional memory.<br />
Neurotrophins are chemicals that<br />
help to stimulate and control<br />
neurogenesis, BDNF being one of<br />
the most active. “T” allele carriers<br />
had lower blood BDNF than CC<br />
BDNF <strong>Gene</strong>ral Health / Cognitive CC TT<br />
BDNF <strong>Gene</strong>ral Health / Cognitive TT CT