Gene Variant Report issued

Lifestyle Genomics Research Centre Ltd.
Plymouth Science Park, 1 Davy Road, Derriford, Plymouth, PL6 8BX , UNITED KINGDOM contact us
SAMPLE PROCESSED BY:
METHOD:
DATA CHECKED FOR ACCURACY BY:
Genome Centre at BARTS and The London School of Medicine and Dentistry
Fluidigm TaqMan probe-based SNP genotyping / Illumina MiSeq, Next Generation
sequencing
Genome Centre at BARTS and The London School of Medicine and Dentistry
NOTES:
genotype has no risk alleles
genotype has one risk allele
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genotype has two risk allels
either allele can be a risk or be
beneficial
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SNP RSID INTERPRET ☞ PARENT GENE & VARIANT ⚛ CATEGORY ☤ / PATHWAY ⥹ RISK ALLELES !! cp00035774
rs3087243 rs3087243 CTLA4
rs11575839 rs11575839 HLA-C
rs10484554 rs10484554 HLA-C
rs2187668 rs2187668 HLA-DQA1
rs9275224
rs3135391
rs3135388
Helps to recognise foreign particles
when they enter our body and fight
them away in an immune response.
Increases risk for
autoimmunity/inflammation to
toxins or infections. Each A
allele=very significant increase in
autoimmune disease risk.
rs3135388
HLA-DQA2
HLA-DRB1
HLA-DRB5/HLA-DRB1/HLA-DRA/HLA-
DQB1/ HLA-DQA1
Immune Factors & Inflammation /
Autoimmunity
Immune Factors & Inflammation /
Autoimmunity
Immune Factors & Inflammation /
Autoimmunity
Immune Factors & Inflammation /
Autoimmunity
Immune Factors & Inflammation /
Autoimmunity
Immune Factors & Inflammation /
Autoimmunity
Immune Factors & Inflammation /
Autoimmunity
A,G
AA
TT
AA
AA
AA
AA
GG
GG
CC
CC
GG
GG
GG