Gene Variant Report issued
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Lifestyle Genomics Research Centre Ltd.<br />
Plymouth Science Park, 1 Davy Road, Derriford, Plymouth, PL6 8BX , UNITED KINGDOM contact us<br />
SAMPLE PROCESSED BY:<br />
METHOD:<br />
DATA CHECKED FOR ACCURACY BY:<br />
Genome Centre at BARTS and The London School of Medicine and Dentistry<br />
Fluidigm TaqMan probe-based SNP genotyping / Illumina MiSeq, Next <strong>Gene</strong>ration<br />
sequencing<br />
Genome Centre at BARTS and The London School of Medicine and Dentistry<br />
NOTES:<br />
genotype has no risk alleles<br />
genotype has one risk allele<br />
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genotype has two risk allels<br />
either allele can be a risk or be<br />
beneficial<br />
Ctr+F to activate Search Engine: Look up genes, rsids, pathways / traits<br />
SNP RSID INTERPRET ☞ PARENT GENE & VARIANT ⚛ CATEGORY ☤ / PATHWAY ⥹ RISK ALLELES !! cp00035774<br />
rs4833095<br />
Toll Like Receptors get activated<br />
mainly by bacterial, viral and fungal<br />
products. Some of our junk protein<br />
can also activate TLRs. Once<br />
activated, they start a cascade that<br />
will produce cytokines and other<br />
inflammatory mediators to combat<br />
the infection.<br />
TLR1 Immune Factors & Inflammation TT TT<br />
rs3775291 rs3775291 TLR3 Immune Factors & Inflammation CC CC<br />
rs1061622 rs1061622 TNFRSF1B Immune Factors & Inflammation GG TG<br />
rs3761847 rs3761847 TRAF1 Immune Factors & Inflammation GG AA<br />
rs7775228 rs7775228 HLA-DQB1<br />
Immune Factors & Inflammation /<br />
Allergies<br />
CC<br />
TT<br />
rs231779 rs231779 CTLA4<br />
Immune Factors & Inflammation /<br />
Autoimmunity<br />
TT<br />
TT<br />
rs231775 rs231775 CTLA4<br />
Immune Factors & Inflammation /<br />
Autoimmunity<br />
GG<br />
GG
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