18.02.2019 Views

Gene Variant Report issued

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Lifestyle Genomics Research Centre Ltd.<br />

Plymouth Science Park, 1 Davy Road, Derriford, Plymouth, PL6 8BX , UNITED KINGDOM contact us<br />

SAMPLE PROCESSED BY:<br />

METHOD:<br />

DATA CHECKED FOR ACCURACY BY:<br />

Genome Centre at BARTS and The London School of Medicine and Dentistry<br />

Fluidigm TaqMan probe-based SNP genotyping / Illumina MiSeq, Next <strong>Gene</strong>ration<br />

sequencing<br />

Genome Centre at BARTS and The London School of Medicine and Dentistry<br />

NOTES:<br />

genotype has no risk alleles<br />

genotype has one risk allele<br />

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genotype has two risk allels<br />

either allele can be a risk or be<br />

beneficial<br />

Ctr+F to activate Search Engine: Look up genes, rsids, pathways / traits<br />

SNP RSID INTERPRET ☞ PARENT GENE & VARIANT ⚛ CATEGORY ☤ / PATHWAY ⥹ RISK ALLELES !! cp00035774<br />

rs1867277<br />

The FOXE1 protein regulates the<br />

transcription of thyroglobulin (Tg)<br />

and thyroid peroxidase (TPO).AA=<br />

production of FOXE1 gene is<br />

increased (by forming a complex<br />

with USF1/USF2 transcription<br />

factors).The higher level of<br />

production of FOXE1 gene<br />

associated with development of<br />

thyroid cancer.<br />

FOXE1 <strong>Gene</strong>ral Health / Thyroid Health AA AA<br />

rs8192678 rs8192678 PPARGC1A <strong>Gene</strong>ral Health <strong>Report</strong> / Blood Glucose TT CT<br />

rs1800961 rs1800961 HNF4A GENERAL INFLAMMATION TT CC<br />

rs3761847 rs3761847 TRAF1 <strong>Gene</strong>ral Inflammation / Bone Health GG AA<br />

rs7041 rs7041 GC <strong>Gene</strong>ral Inflammation / Tuberculosis AA CC<br />

rs602662 rs602662 FUT2 GI Health / Crohn'S Disease AA GG<br />

rs2187668 rs2187668 HLA-DQA1 GI Health / Celiac & Gluten Intolerance TT CC<br />

rs7775228 rs7775228 HLA-DQB1 GI Health / Celiac & Gluten Intolerance CC TT<br />

rs1800871 rs1800871 IL10 GI Health / Celiac & Gluten Intolerance AG GG

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