18.02.2019 Views

Gene Variant Report issued

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Lifestyle Genomics Research Centre Ltd.<br />

Plymouth Science Park, 1 Davy Road, Derriford, Plymouth, PL6 8BX , UNITED KINGDOM contact us<br />

SAMPLE PROCESSED BY:<br />

METHOD:<br />

DATA CHECKED FOR ACCURACY BY:<br />

Genome Centre at BARTS and The London School of Medicine and Dentistry<br />

Fluidigm TaqMan probe-based SNP genotyping / Illumina MiSeq, Next <strong>Gene</strong>ration<br />

sequencing<br />

Genome Centre at BARTS and The London School of Medicine and Dentistry<br />

NOTES:<br />

genotype has no risk alleles<br />

genotype has one risk allele<br />

READ THIS FIRST JOIN US ON FACEBOOK BOOK AN APPOINTMENT<br />

genotype has two risk allels<br />

either allele can be a risk or be<br />

beneficial<br />

Ctr+F to activate Search Engine: Look up genes, rsids, pathways / traits<br />

SNP RSID INTERPRET ☞ PARENT GENE & VARIANT ⚛ CATEGORY ☤ / PATHWAY ⥹ RISK ALLELES !! cp00035774<br />

rs4833095<br />

Toll Like Receptors get activated<br />

mainly by bacterial, viral and fungal<br />

products. Some of our junk protein<br />

can also activate TLRs. Once<br />

activated, they start a cascade that<br />

will produce cytokines and other<br />

inflammatory mediators to combat<br />

the infection.<br />

TLR1 <strong>Gene</strong>ral Health / Hayfever TT TT<br />

rs1049793 rs1049793 AOC1 / DAO <strong>Gene</strong>ral Health / Histamine Metabolism GG CG<br />

rs3918347 rs3918347 DAO <strong>Gene</strong>ral Health / Histamine Metabolism GG AG<br />

rs2073440 Histidine to Histamine HDC <strong>Gene</strong>ral Health / Histamine Metabolism GG TG<br />

rs901865 Histamine Receptor HRH1 <strong>Gene</strong>ral Health / Histamine Metabolism TT TC<br />

rs16940765 Histamine Receptor HRH4 <strong>Gene</strong>ral Health / Histamine Metabolism CC TT<br />

rs11662595 Histamine Receptor HRH4 <strong>Gene</strong>ral Health / Histamine Metabolism GG AA<br />

rs1799836 rs1799836 MAOB <strong>Gene</strong>ral Health / Histamine Metabolism TT TC<br />

rs1799929 rs1799929 NAT2 <strong>Gene</strong>ral Health / Histamine Metabolism TT TT<br />

rs1208 rs1208 NAT2 <strong>Gene</strong>ral Health / Histamine Metabolism GG GG<br />

rs1799930 rs1799930 NAT2 <strong>Gene</strong>ral Health / Histamine Metabolism AA GG

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