18.02.2019 Views

Gene Variant Report issued

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Lifestyle Genomics Research Centre Ltd.<br />

Plymouth Science Park, 1 Davy Road, Derriford, Plymouth, PL6 8BX , UNITED KINGDOM contact us<br />

SAMPLE PROCESSED BY:<br />

METHOD:<br />

DATA CHECKED FOR ACCURACY BY:<br />

Genome Centre at BARTS and The London School of Medicine and Dentistry<br />

Fluidigm TaqMan probe-based SNP genotyping / Illumina MiSeq, Next <strong>Gene</strong>ration<br />

sequencing<br />

Genome Centre at BARTS and The London School of Medicine and Dentistry<br />

NOTES:<br />

genotype has no risk alleles<br />

genotype has one risk allele<br />

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genotype has two risk allels<br />

either allele can be a risk or be<br />

beneficial<br />

Ctr+F to activate Search Engine: Look up genes, rsids, pathways / traits<br />

SNP RSID INTERPRET ☞ PARENT GENE & VARIANT ⚛ CATEGORY ☤ / PATHWAY ⥹ RISK ALLELES !! cp00035774<br />

rs662 rs662 PON1 Q192R<br />

rs1816702 rs1816702 TLR2<br />

rs4986791 rs4986791 TLR4<br />

rs4986790 rs4986790 TLR4<br />

rs6853 rs6853 MYD88<br />

rs4986790 rs4986790 TLR4<br />

Immune Factors & Inflammation /<br />

Microbial defence<br />

Immune Factors & Inflammation /<br />

Microbial defence<br />

Immune Factors & Inflammation /<br />

Microbial defence<br />

Immune Factors & Inflammation /<br />

Microbial defence<br />

Immune Factors & Inflammation /<br />

Vaccine Response<br />

Immune Factors & Inflammation /<br />

Vaccine Response<br />

rs1800871 rs1800871 IL10 Immune Factors and Inflammation AA GG<br />

rs1878672 rs1878672 IL10 Immune Factors and Inflammation CC CC<br />

rs3024490 rs3024490 IL10 Immune Factors and Inflammation AA CC<br />

rs20541 rs20541 IL13 Immune Factors and Inflammation AA GG<br />

rs1143643 rs1143643 IL1B Immune Factors and Inflammation CC CC<br />

rs16944 rs16944 IL1B Immune Factors and Inflammation GG AA<br />

TT<br />

TT<br />

TT<br />

GG<br />

GG<br />

GG<br />

CC<br />

CC<br />

CC<br />

AA<br />

AA<br />

AA

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