18.02.2019 Views

Gene Variant Report issued

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Lifestyle Genomics Research Centre Ltd.<br />

Plymouth Science Park, 1 Davy Road, Derriford, Plymouth, PL6 8BX , UNITED KINGDOM contact us<br />

SAMPLE PROCESSED BY:<br />

METHOD:<br />

DATA CHECKED FOR ACCURACY BY:<br />

Genome Centre at BARTS and The London School of Medicine and Dentistry<br />

Fluidigm TaqMan probe-based SNP genotyping / Illumina MiSeq, Next <strong>Gene</strong>ration<br />

sequencing<br />

Genome Centre at BARTS and The London School of Medicine and Dentistry<br />

NOTES:<br />

genotype has no risk alleles<br />

genotype has one risk allele<br />

READ THIS FIRST JOIN US ON FACEBOOK BOOK AN APPOINTMENT<br />

genotype has two risk allels<br />

either allele can be a risk or be<br />

beneficial<br />

Ctr+F to activate Search Engine: Look up genes, rsids, pathways / traits<br />

SNP RSID INTERPRET ☞ PARENT GENE & VARIANT ⚛ CATEGORY ☤ / PATHWAY ⥹ RISK ALLELES !! cp00035774<br />

rs266729<br />

rs10885122<br />

Adiponectin is released in the<br />

bloodstream from fat cells, where it<br />

is involved in the control of fat<br />

metabolism and regulating glucose<br />

levels .CG was associated with type<br />

2 diabetes in the obese group only<br />

OR=2.45....P=0.02, and 59% risk of<br />

diabetes could be attributed to that.<br />

T=lower fasting glucoseG=higher<br />

fasting glucose<br />

ADIPOQ <strong>Gene</strong>ral Health / Blood Glucose GG CG<br />

ADRA2A <strong>Gene</strong>ral Health / Blood Glucose GG GG<br />

rs1405655 rs1405655 LXR <strong>Gene</strong>ral Health / Blood Glucose TT TT<br />

rs17373080 rs17373080 LXR <strong>Gene</strong>ral Health / Blood Glucose GG CC<br />

rs2695121 rs2695121 LXR <strong>Gene</strong>ral Health / Blood Glucose TT CC<br />

rs3135506<br />

The C (minor) allele is associated<br />

with:<br />

Higher risk of Cardiovascular<br />

disease.<br />

APOA5 <strong>Gene</strong>ral Health / Cardiovascular Health CC GG

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