Gene Variant Report issued

Recommendations

Info

Lifestyle Genomics Research Centre Ltd. Plymouth Science Park, 1 Davy Road, Derriford, Plymouth, PL6 8BX , UNITED KINGDOM contact us SAMPLE PROCESSED BY: METHOD: DATA CHECKED FOR ACCURACY BY: Genome Centre at BARTS and The London School of Medicine and Dentistry Fluidigm TaqMan probe-based SNP genotyping / Illumina MiSeq, Next <strong>Gene</strong>ration sequencing Genome Centre at BARTS and The London School of Medicine and Dentistry NOTES: genotype has no risk alleles genotype has one risk allele READ THIS FIRST JOIN US ON FACEBOOK BOOK AN APPOINTMENT genotype has two risk allels either allele can be a risk or be beneficial Ctr+F to activate Search Engine: Look up genes, rsids, pathways / traits SNP RSID INTERPRET ☞ PARENT GENE & VARIANT ⚛ CATEGORY ☤ / PATHWAY ⥹ RISK ALLELES !! cp00035774 rs2551715 Oxidised Glutathione reduction GSR Chemoprotection / Oxidative Stress TT CC rs1799836 rs1799836 MAOB Chemoprotection / Oxidative Stress TT TC rs35652124 rs35652124 NFE2L2 or NRF2 Chemoprotection / Oxidative Stress TT TC rs1962142 rs1962142 NFE2L2 or NRF2 Chemoprotection / Oxidative Stress AA GG rs6726395 rs6726395 NFE2L2 or NRF2 Chemoprotection / Oxidative Stress AA AG rs1800566 rs1800566 NQO1 Chemoprotection / Oxidative Stress AA GG rs854571 rs854571 PON1 Chemoprotection / Oxidative Stress TT TC rs662 rs662 PON1 Q192R Chemoprotection / Oxidative Stress TT CC rs4880 rs4880 SOD2 Chemoprotection / Oxidative Stress GG GG rs2069840 rs2069840 IL6 Chemoprotection / Oxidative Stress / Immune Factor GG CC rs9282861 rs9282861 SULT1A1 Chemoprotection / Sulfonation CC CC rs182420 rs182420 SULT2A1 Chemoprotection / Sulfonation CC CT rs2547231 rs2547231 SULT2A1 Chemoprotection / Sulfonation AA CA rs11605924 A (major) = Reduction in energy utilisation in a high fat diet. CRY2 Diet & Nutrition AA AA rs602662 rs602662 FUT2 Diet & Nutrition / B12 Status AA GG
Lifestyle Genomics Research Centre Ltd. Plymouth Science Park, 1 Davy Road, Derriford, Plymouth, PL6 8BX , UNITED KINGDOM contact us SAMPLE PROCESSED BY: METHOD: DATA CHECKED FOR ACCURACY BY: Genome Centre at BARTS and The London School of Medicine and Dentistry Fluidigm TaqMan probe-based SNP genotyping / Illumina MiSeq, Next <strong>Gene</strong>ration sequencing Genome Centre at BARTS and The London School of Medicine and Dentistry NOTES: genotype has no risk alleles genotype has one risk allele READ THIS FIRST JOIN US ON FACEBOOK BOOK AN APPOINTMENT genotype has two risk allels either allele can be a risk or be beneficial Ctr+F to activate Search Engine: Look up genes, rsids, pathways / traits SNP RSID INTERPRET ☞ PARENT GENE & VARIANT ⚛ CATEGORY ☤ / PATHWAY ⥹ RISK ALLELES !! cp00035774 rs1801198 rs1801198 TCN2 Diet & Nutrition / B12 transport GG GC rs9606756 rs9606756 TCN2 Diet & Nutrition / B12 transport GG AA rs4148211 rs708272 The G (minor) allele is associated with: Increased total cholesterol levels Increased levels of LDL cholesterol but Decreased risk of developing type 2 diabetesThe A (major) allele is associated with: Increased levels of triglycerides (AA).Low levels of LDL cholesterol (AA).but Increased risk of developing type 2 diabetes (AA). The “C” (major) allele is associated with decreased levels of HDL (good cholesterol).The “A” allele is associated with increased HDL levels. ABCG8 Diet & Nutrition / Cholesterol Status GG AA CETP Diet & Nutrition / Cholesterol Status GG GG
Page 1 and 2: Lifestyle Genomics Research Centre
Page 5: Lifestyle Genomics Research Centre

Gene Variant Report issued

Create successful ePaper yourself

Delete template?

Save as template?