Gene Variant Report issued
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Lifestyle Genomics Research Centre Ltd.<br />
Plymouth Science Park, 1 Davy Road, Derriford, Plymouth, PL6 8BX , UNITED KINGDOM contact us<br />
SAMPLE PROCESSED BY:<br />
METHOD:<br />
DATA CHECKED FOR ACCURACY BY:<br />
Genome Centre at BARTS and The London School of Medicine and Dentistry<br />
Fluidigm TaqMan probe-based SNP genotyping / Illumina MiSeq, Next <strong>Gene</strong>ration<br />
sequencing<br />
Genome Centre at BARTS and The London School of Medicine and Dentistry<br />
NOTES:<br />
genotype has no risk alleles<br />
genotype has one risk allele<br />
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genotype has two risk allels<br />
either allele can be a risk or be<br />
beneficial<br />
Ctr+F to activate Search Engine: Look up genes, rsids, pathways / traits<br />
SNP RSID INTERPRET ☞ PARENT GENE & VARIANT ⚛ CATEGORY ☤ / PATHWAY ⥹ RISK ALLELES !! cp00035774<br />
rs1799945 rs1799945 HFE <strong>Gene</strong>ral Health / Cardiovascular Health GG CG<br />
rs3869109 rs3869109 HLA-C <strong>Gene</strong>ral Health / Cardiovascular Health GG AG<br />
rs5443 rs5443 HTR2A <strong>Gene</strong>ral Health / Cardiovascular Health TT CT<br />
rs8192678 rs8192678 PPARGC1A <strong>Gene</strong>ral Health / Cardiovascular Health TT CT<br />
rs4961<br />
The risk (T) allele responded better<br />
to diuretics and sodium-restricted<br />
diets, in that they tended to lower<br />
their blood pressure by ~10 mmHg<br />
points compared to rs4961(G;G)<br />
homozygotes similarly treated.<br />
ADD1 <strong>Gene</strong>ral Health / Clotting Factors TT GG<br />
rs1800775<br />
CETP encodes a protein that is<br />
involved in the transfer of<br />
cholesteryl ester from high density<br />
CETP <strong>Gene</strong>ral Health / Clotting Factors CC CC<br />
lipoprotein (HDL) to other<br />
lipoproteins.<br />
rs13146272 rs13146272 CYP4V2 <strong>Gene</strong>ral Health / Clotting Factors CC AA
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