18.02.2019 Views

Gene Variant Report issued

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Lifestyle Genomics Research Centre Ltd.<br />

Plymouth Science Park, 1 Davy Road, Derriford, Plymouth, PL6 8BX , UNITED KINGDOM contact us<br />

SAMPLE PROCESSED BY:<br />

METHOD:<br />

DATA CHECKED FOR ACCURACY BY:<br />

Genome Centre at BARTS and The London School of Medicine and Dentistry<br />

Fluidigm TaqMan probe-based SNP genotyping / Illumina MiSeq, Next <strong>Gene</strong>ration<br />

sequencing<br />

Genome Centre at BARTS and The London School of Medicine and Dentistry<br />

NOTES:<br />

genotype has no risk alleles<br />

genotype has one risk allele<br />

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genotype has two risk allels<br />

either allele can be a risk or be<br />

beneficial<br />

Ctr+F to activate Search Engine: Look up genes, rsids, pathways / traits<br />

SNP RSID INTERPRET ☞ PARENT GENE & VARIANT ⚛ CATEGORY ☤ / PATHWAY ⥹ RISK ALLELES !! cp00035774<br />

rs2229765<br />

IGF1R encodes for insulin growth<br />

factor receptors; overexpression<br />

can stop cell death by enhancing<br />

cell survival and is present in<br />

malignant tissues. AA= lower levels<br />

of IGF-1 protein.Increased longevity<br />

in males 15% of people have AA.<br />

Most people have AG.<br />

IGF1R Immune Factors & Inflammation / IgA AA GG<br />

rs9357155 rs9357155 PSMB8 Immune Factors & Inflammation / IgA AA GG

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