18.02.2019 Views

Gene Variant Report issued

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Lifestyle Genomics Research Centre Ltd.<br />

Plymouth Science Park, 1 Davy Road, Derriford, Plymouth, PL6 8BX , UNITED KINGDOM<br />

contact us<br />

SAMPLE PROCESSED BY:<br />

METHOD:<br />

DATA CHECKED FOR ACCURACY BY:<br />

Genome Centre at BARTS and The London School of Medicine and Dentistry<br />

Fluidigm TaqMan probe-based SNP genotyping / Illumina MiSeq, Next <strong>Gene</strong>ration<br />

sequencing<br />

Genome Centre at BARTS and The London School of Medicine and Dentistry<br />

NOTES:<br />

genotype has no risk alleles<br />

genotype has one risk allele<br />

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genotype has two risk allels<br />

either allele can be a risk or be<br />

beneficial<br />

Ctr+F to activate Search Engine: Look up genes, rsids, pathways / traits<br />

SNP RSID INTERPRET ☞ PARENT GENE & VARIANT ⚛ CATEGORY ☤ / PATHWAY ⥹ RISK ALLELES !! cp00035774<br />

rs174537<br />

The G (major) allele is associated<br />

with increased LDL cholesterol (bad<br />

cholesterol) levels.The T (minor)<br />

allele is associated with decreased<br />

LDL cholesterol (bad cholesterol)<br />

levels.<br />

MYRF Diet & Nutrition / Cholesterol Status GG GT<br />

rs7946 rs7946 PEMT Diet & Nutrition / Cholesterol Status TT TT<br />

rs2016520<br />

The T (major) allele is associated<br />

with increased cholesterol levels.<br />

PPARD Diet & Nutrition / Cholesterol Status TT TT<br />

rs8192678 rs8192678 PPARGC1A Diet & Nutrition / Cholesterol Status TT CT<br />

rs646776<br />

The C (minor) allele is associated<br />

with increased levels of LDL (bad<br />

cholesterol).<br />

PSRC1 Diet & Nutrition / Cholesterol Status CC TT

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