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Gene Variant Report issued

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Lifestyle Genomics Research Centre Ltd.<br />

Plymouth Science Park, 1 Davy Road, Derriford, Plymouth, PL6 8BX , UNITED KINGDOM contact us<br />

SAMPLE PROCESSED BY:<br />

METHOD:<br />

DATA CHECKED FOR ACCURACY BY:<br />

Genome Centre at BARTS and The London School of Medicine and Dentistry<br />

Fluidigm TaqMan probe-based SNP genotyping / Illumina MiSeq, Next <strong>Gene</strong>ration<br />

sequencing<br />

Genome Centre at BARTS and The London School of Medicine and Dentistry<br />

NOTES:<br />

genotype has no risk alleles<br />

genotype has one risk allele<br />

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genotype has two risk allels<br />

either allele can be a risk or be<br />

beneficial<br />

Ctr+F to activate Search Engine: Look up genes, rsids, pathways / traits<br />

SNP RSID INTERPRET ☞ PARENT GENE & VARIANT ⚛ CATEGORY ☤ / PATHWAY ⥹ RISK ALLELES !! cp00035774<br />

rs3211719<br />

rs6025<br />

rs6048<br />

This gene encodes a protein called<br />

coagulation factor X that helps<br />

blood clot after an injury. Mutations<br />

can cause deficiency of the protein,<br />

which leads to excessive bleeding.<br />

he F5 gene encodes a protein that is<br />

called coagulation factor V. They<br />

that form blood clots to stop<br />

bleeding and trigger blood vessel<br />

repair after an injury. Mutations can<br />

cause abnormal bleeding.<br />

This gene encodes a protein called<br />

coagulation factor IX, which helps<br />

form blood clots. Mutations can<br />

cause blood clots to be unable to<br />

form and lead to excessive bleeding<br />

(hemophilia) or warfarin sensitivity,<br />

which can cause severe bleeding<br />

problems.<br />

F10 <strong>Gene</strong>ral Health / Clotting Factors GG AA<br />

F5 <strong>Gene</strong>ral Health / Clotting Factors TT CC<br />

F9 <strong>Gene</strong>ral Health / Clotting Factors GG GG

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