Gene Variant Report issued
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Lifestyle Genomics Research Centre Ltd.<br />
Plymouth Science Park, 1 Davy Road, Derriford, Plymouth, PL6 8BX , UNITED KINGDOM<br />
contact us<br />
SAMPLE PROCESSED BY:<br />
METHOD:<br />
DATA CHECKED FOR ACCURACY BY:<br />
Genome Centre at BARTS and The London School of Medicine and Dentistry<br />
Fluidigm TaqMan probe-based SNP genotyping / Illumina MiSeq, Next <strong>Gene</strong>ration<br />
sequencing<br />
Genome Centre at BARTS and The London School of Medicine and Dentistry<br />
NOTES:<br />
genotype has no risk alleles<br />
genotype has one risk allele<br />
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genotype has two risk allels<br />
either allele can be a risk or be<br />
beneficial<br />
Ctr+F to activate Search Engine: Look up genes, rsids, pathways / traits<br />
SNP RSID INTERPRET ☞ PARENT GENE & VARIANT ⚛ CATEGORY ☤ / PATHWAY ⥹ RISK ALLELES !! cp00035774<br />
rs659366<br />
The "T" (minor) allele is associated<br />
with:More UCP2 production and<br />
higher levels of UCP2 protein<br />
Increased levels of HDL-Cholestrol<br />
and decreased levels of LDL-<br />
Cholestrol in a Chinese population.<br />
Reduced LDL particle size levels in a<br />
Chinese population.Increased<br />
energy expenditure.Decreased lipid<br />
oxidation Decreased high-sensitivity<br />
Cholesterol reactive protein (hs-<br />
CRP), a biomarker of inflammation.<br />
This decrease may indicate a lower<br />
level of inflammation in the body.<br />
More difficulty in losing weight<br />
under a very low-calorie program in<br />
Korean women.Higher fasting<br />
glucose levels in the blood.Higher<br />
risk of Diabetes (Type 2).Increased<br />
hardening of the arteries in women.<br />
UCP2 Diet & Nutrition / Cholesterol Status CC CT
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