18.02.2019 Views

Gene Variant Report issued

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Lifestyle Genomics Research Centre Ltd.<br />

Plymouth Science Park, 1 Davy Road, Derriford, Plymouth, PL6 8BX , UNITED KINGDOM<br />

contact us<br />

SAMPLE PROCESSED BY:<br />

METHOD:<br />

DATA CHECKED FOR ACCURACY BY:<br />

Genome Centre at BARTS and The London School of Medicine and Dentistry<br />

Fluidigm TaqMan probe-based SNP genotyping / Illumina MiSeq, Next <strong>Gene</strong>ration<br />

sequencing<br />

Genome Centre at BARTS and The London School of Medicine and Dentistry<br />

NOTES:<br />

genotype has no risk alleles<br />

genotype has one risk allele<br />

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genotype has two risk allels<br />

either allele can be a risk or be<br />

beneficial<br />

Ctr+F to activate Search Engine: Look up genes, rsids, pathways / traits<br />

SNP RSID INTERPRET ☞ PARENT GENE & VARIANT ⚛ CATEGORY ☤ / PATHWAY ⥹ RISK ALLELES !! cp00035774<br />

rs17300539<br />

rs174537<br />

The G (major) allele is associated<br />

with:Worse response to<br />

monounsaturated fat intake.GG =<br />

Higher BMI with increased<br />

monounsaturated fat intake (avoid<br />

monounsaturated fats)<br />

The G (major) allele is associated<br />

with:Possible decreased need for<br />

fish oil supplements to maintain<br />

healthy omega-3 fatty acid<br />

levelsIncreased levels of arachidonic<br />

acid in the body [R]. Arachidonic<br />

acid is an Omega-6 polyunsaturated<br />

fatty acid.TT = Possible increased<br />

need for fish oil supplements to<br />

maintain healthy omega-3 fatty acid<br />

levels.TT = Lower levels of<br />

arachidonic acid in the body.<br />

Arachidonic acid is an Omega-6<br />

polyunsaturated fatty acid.<br />

ADIPOQ Diet & Nutrition / Monounsaturated Fat GG GG<br />

MYRF Diet & Nutrition / Omega fatty acids TT GT

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