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Reviewer Comments - EERE

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2011 Algae Platform Review – <strong>Reviewer</strong> <strong>Comments</strong><br />

<strong>Reviewer</strong> <strong>Comments</strong> are direct transcripts of commentary and material provided by the Platform’s<br />

Review Panel. They have not been edited or altered by the Biomass Program.<br />

wastewater. Yes, it is impossible to mitigate uncharacterized risks. This is the main thrust of the proposal.<br />

With new toxins/toxicity or the presence of human pathogens in novel environments, new approaches to<br />

identify the risk and detect the culprit must be carried out first. We will develop analytical measuring<br />

tools such as MS, NMR, LC, Q-PCR, etc. to achieve these goals. These tools, or adaptation of these tools,<br />

will represent a key asset to performing more formal risk assessments.<br />

4. Critical Success Factors<br />

The project has identified critical factors, (including technical, business, market, regulatory, and legal<br />

factors) that impact the potential technical and commercial success of the project<br />

The project has presented adequate plans to recognize, address, and overcome these factors<br />

The project has the opportunity to advance the state of technology and impact the viability of commercial<br />

algal biomass feedstock supply and conversion, through one or more of the following:<br />

i. Cross-Cutting Analysis (ex. economic analysis, sustainability analysis, resource assessments, risk<br />

assessments)<br />

ii. Feedstock Supply R&D (ex. biology, cultivation, resource use, biomass characteristics,<br />

harvesting/dewatering)<br />

iii. Downstream Refining R&D (ex. extraction, conversion, fuel, products, fuel/product infrastructure and<br />

end-use)<br />

iv. Environmental sustainability (example: water use, GMOs, energy consumption)<br />

<strong>Reviewer</strong> <strong>Comments</strong><br />

<strong>Reviewer</strong>: 1 Criteria Score: 3<br />

The CSFs are the same as the other presentation on this Project. See the same comments. I do not think<br />

these adequately address the success of the project, which is of high significance overall, but requires<br />

some real assessment of what success means in the human health assessment. Input from EPA would be<br />

expected to be important.<br />

<strong>Reviewer</strong>: 2 Criteria Score: 2<br />

The project appears unaware of the NOAA Oceans and Human Health Centers, as well as the vast<br />

experience of the FDA and CDC in the stated area of research of the project.<br />

<strong>Reviewer</strong>: 3 Criteria Score: 4<br />

There is a need to establish the strains of algae to be investigated and justify the selection. Are the strains<br />

to be investigated the ones that would be used for biofuels production? If not, the work would find no<br />

application.<br />

<strong>Reviewer</strong>: 4 Criteria Score: 3<br />

See other comments.<br />

<strong>Reviewer</strong>: 5 Criteria Score: 3<br />

Critical success factors were identified but the plans to address a major obstacle (relevance of assessment<br />

results) seem inadequate.<br />

<strong>Reviewer</strong>: 6 Criteria Score: 3<br />

No real information was given as to the pre-existing knowledge of toxins to screen for, or as to the reason<br />

behind the screens chosen. This part of lacking.<br />

Page 163 of 223

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