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Reviewer Comments - EERE

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2011 Algae Platform Review – <strong>Reviewer</strong> <strong>Comments</strong><br />

<strong>Reviewer</strong> <strong>Comments</strong> are direct transcripts of commentary and material provided by the Platform’s<br />

Review Panel. They have not been edited or altered by the Biomass Program.<br />

Presenter Response<br />

3. Project Relevance<br />

The project both identifies with and contributes to meeting the platform goals and objectives of the<br />

Biomass Program Multi-Year Program Plan<br />

The project has considered applications of the expected outputs<br />

<strong>Reviewer</strong> <strong>Comments</strong><br />

<strong>Reviewer</strong>: 1 Criteria Score: 4<br />

There are some good outcomes that have relevance. There are others that do not.<br />

<strong>Reviewer</strong>: 2 Criteria Score: 3<br />

PIs should refocus on core goals/milestones and do costing/scale-up calculations to justify that this is a<br />

sustainable biofuels' production process. In the absence of this, the types of processes and materials being<br />

developed and the bioreactor system itself raises conerns about the amount of energy input required to the<br />

biofuel's derived energy that will be available.<br />

<strong>Reviewer</strong>: 3 Criteria Score: 7<br />

- Development of an understanding of TAG oil formation in lipid bodies after N deprivation of<br />

microalgae, including de novo synthesis vs. redistribution of membrane lipids. - Development of novel<br />

nanobody based membrane linkage and cell harvesting systems.<br />

<strong>Reviewer</strong>: 4 Criteria Score: 2<br />

See Overall Impression text.<br />

<strong>Reviewer</strong>: 5 Criteria Score: 3<br />

Unfortunately, the project's approach and results do not seem relevant to meeting platform goals and<br />

objectives.<br />

<strong>Reviewer</strong>: 6 Criteria Score: 2<br />

One cannot be relevant until the work is appropriately placed in the reports by Benneman and co-authors.<br />

<strong>Reviewer</strong>: 7 Criteria Score: 3<br />

The engineered nano antibody work does not appeear to have commerical potential at scale.<br />

The reasoning for pursuing PBRs was vague and non-technical and did not show a pathway to overcome<br />

cost issues for PBRs that have been shown in techno-economic modeling.<br />

Presenter Response<br />

4. Critical Success Factors<br />

The project has identified critical factors, (including technical, business, market, regulatory, and legal<br />

factors) that impact the potential technical and commercial success of the project<br />

The project has presented adequate plans to recognize, address, and overcome these factors<br />

The project has the opportunity to advance the state of technology and impact the viability of commercial<br />

algal biomass feedstock supply and conversion, through one or more of the following:<br />

Page 40 of 223

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