4th EucheMs chemistry congress

Monday, 27-Aug 2012
s596
chem. Listy 106, s587–s1425 (2012)
Analytical chemistry Electrochemistry, Analysis, sample manipulation
Electroanalytical methods - ii
o - 0 0 7
nAnoteChnoLoGy And MuLtiAnALyte
PLAtforM fLow SySteMS
J. K. f. vAn StAden 1 , r. i. vAn StAden 1
1 INCDEMC Timisoara Timus Romania, PATLABProcess
Analytical Technology Laboratory, Bucharest, Romania
Email: koosvanstaden@yahoo.com www.patlab.ro,
Sustainable development forms a key objective of the
European Union with primary concern about natural resources
(waste water management, water quality and quantity), food
processing and distribution, health issues, climate change, clean
energy as some key issues. This can be seen from the large
number of research consortiums with current projects from the
European Commission where Nanotechnology is one of the main
areas with a budget reaching into millions of Euros. As a result
microsystems technology with PAT, MPAT and NPAT become
increasingly important in various operations in real-time and new
innovations linking the different PAT systems successfully to
microsystems technology may create fruitful solutions to the
problems above. It will be shown how the establishment of
PATLAB in Bucharest, Romania served as a catalyst for PAT,
MPAT and NPAT. Different scenarios regarding the innovation,
development, implementation and application of flow-based
systems will be outlined. This will be compared with
non-flow-based systems. Careful attention will be given to the
reality of microfluidics as marketable applications with flowbased
PAT, MPAT and NPAT, the incorporations of micro- or/and
nanosensors as detection devices and if real-time is always
possible. It will be discussed if there is any improvement in the
configuration and construction of downscaled chemically devices
and if the movement to remote sensing with innovation of
high performance real-time intelligent interactive multi-point
multi-species process analytical technological microsystems show
that a marriage between these devices are possible. The reality of
the current situation with possible future solutions will be
highlighted and outlined.
Acknowledgements: The authors would like to acknowledge
the financial support received from the project Program Ideas
PN-II-ID-PCE-2011-3-0538/2012-2014, financed by contract
100/27-10-2011.
Keywords: nanotechnology; multianalyte; microsystems; flow
systems;
Electroanalytical methods - iii
4 th EucheMs chemistry congress
o - 0 0 8
eLeCtroCheMiStry CouPLed to
eLeCtroSPrAy MASS SPeCtroMetry
L. nyhoLM 1
1 Uppsala University, Department of Chemistry - The Angström
laboratory, Uppsala, Sweden
The on-line coupling of electrochemistry (EC) to
electrospray mass spectrometry (ESI-MS) provides a very
powerful tool for studies of electroactive compounds and
electrochemical reactions. With EC/ESI-MS it is possible to
identify and quantitate electrochemically produced oxidation and
reduction products1,2 . It is also possible to utilise electrochemical
reactions for preconcentration and/or ionisation of selected
analytes, as well as for tagging purposes3 . The coupling of
electrochemical cells to ESI-MS, however, requires decoupling
of the electrochemical cell from the ESI-MS high voltage, and is
also complicated by the fact that the electrospray process itself
involves electrochemical reactions. Care also needs to be taken
to ensure that the electrochemically generated products do not
undergo unwanted redox reactions between the electrochemical
cell and the mass spectrometer4 and to reduce the transfer time
between the electrochemical cell and the mass spectrometer5 .
In the present communication, the advantages and
limitations of combining electrochemistry and ESI-MS technique
will be discussed based on selected applications. It will be
demonstrated that the choice of electrolyte as well as the design
of the electrochemical cell and the flow system, can affect the
obtained mass spectra and the possibilities to detect
electrochemically generated species.
references:
1. J. Gun, S. Bharathi, V. Gutkin, D. Rizkov, A. Voloshenko,
R. Shelkov, S. Sladkevich, N. Kyi, M. Rona, Y. Wolanov,
D. Rizkov, M. Koch, S. Mizrathi, P. V. Pridkhochenko,
A. Modestov, O. Lev, Isr. J. Chem., 50 (2010) 360.
2. C. Zettersten, Ph. D. Thesis, Uppsala University, 2009.
3. T. C. Rohner, J. S. Rossier and H. H. Girault, Electrochem.
Commun., 4 (2002) 695.
4. F. C. Bökman, C. Zettersten, P. J. R. Sjöberg and
L. Nyholm, Anal. Chem., 76 (2004) 2017.
5. G. Liljegren, A. Dahlin, C. Zettersten, J. Bergquist and
L. Nyholm, Lab Chip, 5 (2005) 1008.
Keywords: Electrochemistry; mass spectrometry; Analytical
Methods; Oxidation; Redox chemistry;
AUGUst 26–30, 2012, PrAGUE, cZEcH rEPUbLIc