4th EucheMs chemistry congress

thursday, 30-Aug 2012
s592
chem. Listy 106, s587–s1425 (2012)
Plenary lectures
Plenary lecture iX
P L - 0 9
deSiGn And APPLiCAtionS of SeLeCtive
reACtionS of oLefinS
r. h. GruBBS 1
1 California Institute of Technology, Department of Chemistry
and Chemical Engineering, Pasadena, USA
Olefin metathesis catalysts have become one of the tools for
the efficient synthesis of complex molecules. Until recently, the
catalysts demonstrated poor catalyst controlled selectivity. Over
the past couple of years, complexes based on molybdenum,
tungsten and ruthenium have been discovered that will produce
olefins good to excellent selectivity for the generation of Z olefins
both in cross and ring closing metathesis. New ligands have been
developed that result in different selectivities and open new
applications of metathesis in the synthesis of an array of complex
molecules.
Keywords: olefin; metathesis; catalysts; ruthenium;
4 th EucheMs chemistry congress
AUGUst 26–30, 2012, PrAGUE, cZEcH rEPUbLIc