Traditional Medicine in Asia
Traditional Medicine in Asia
Traditional Medicine in Asia
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to give priority to research and development<br />
of traditional medic<strong>in</strong>es. The health<br />
policy of Ch<strong>in</strong>a aims at <strong>in</strong>tegrat<strong>in</strong>g modern<br />
medic<strong>in</strong>e with the traditional Ch<strong>in</strong>ese<br />
medic<strong>in</strong>es and conduct<strong>in</strong>g research <strong>in</strong><br />
traditional practices <strong>in</strong> a rational way. India<br />
has set up the Central Council for Research<br />
<strong>in</strong> Ayurveda and Siddha (CCRAS) and<br />
Unani systems to <strong>in</strong>vestigate a number of<br />
herbal medic<strong>in</strong>es to establish the scientific<br />
basis of their use. The Indian Council of<br />
Medical Research has established a<br />
programme of Composite Drug Research<br />
(CDR) whereby herbal drugs are <strong>in</strong>vestigated<br />
by a team of traditional and modern<br />
medic<strong>in</strong>e practitioners, a botanist, a<br />
phytochemist and a pharmacologist <strong>in</strong> a<br />
coord<strong>in</strong>ated manner.<br />
More than a hundred medic<strong>in</strong>al plants<br />
used <strong>in</strong> Ayurveda have been <strong>in</strong>vestigated<br />
<strong>in</strong> the CDR scheme and have provided<br />
some promis<strong>in</strong>g leads for further<br />
<strong>in</strong>vestigation. In some cases, the therapeutic<br />
claims made by Ayurveda practitioners<br />
have been justified by pharmacological<br />
studies. The plants selected <strong>in</strong> CDR<br />
have been botanically identified and their<br />
pharmacognostic data have been<br />
reported. Phytochemical studies have<br />
yielded some novel chemical structures. 2<br />
Thus, the Satavari (Asparagus racemosus)<br />
root used <strong>in</strong> Ayurveda as a galactogogue<br />
was studied <strong>in</strong> experimental animals and<br />
reported to possess galactogogue and<br />
anti-oxytosic activities. (3,4) The plant is<br />
reported to conta<strong>in</strong> Shatavar<strong>in</strong> hav<strong>in</strong>g a<br />
specific pharmacological action. Picrorhiza<br />
kurroa has been reported to posses<br />
hepatoprotective activity and its active<br />
pr<strong>in</strong>ciples have been identified as<br />
Picrocytes. Butea frondosa, which is used<br />
<strong>in</strong> Ayurvedic preparations as an anthelm<strong>in</strong>tic,<br />
has yielded an active pr<strong>in</strong>ciple called<br />
palason<strong>in</strong>. Guggulisterone from guggul<br />
res<strong>in</strong> has been isolated. 2 The res<strong>in</strong> is used<br />
Research, drug development and manufacture of herbal drugs<br />
extensively by traditional practitioners <strong>in</strong> the<br />
treatment of <strong>in</strong>flammation of jo<strong>in</strong>ts, obesity,<br />
lipid disorders, etc., on the basis of the<br />
description of Medorog (Lipid disorder) by<br />
Susruta. Chemical <strong>in</strong>vestigation has yielded<br />
two active compounds, namely z-<br />
Guggulsterone and e-Guggulsterone. 5 It<br />
is evident that such a composite approach<br />
<strong>in</strong> the <strong>in</strong>vestigation of medic<strong>in</strong>al plants is<br />
likely to be more reward<strong>in</strong>g <strong>in</strong> establish<strong>in</strong>g<br />
the therapeutic claims of traditional<br />
remedies and obta<strong>in</strong><strong>in</strong>g novel chemical<br />
entities.<br />
Thailand, Indonesia, Vietnam, Sri Lanka<br />
and Nepal, have all given priority to<br />
research <strong>in</strong> traditional medic<strong>in</strong>es <strong>in</strong> their<br />
health and drug policies. Several countries<br />
have established pharmacopoeias of<br />
traditional medic<strong>in</strong>es and established<br />
<strong>in</strong>stitutes to undertake research <strong>in</strong> all<br />
aspects, <strong>in</strong>clud<strong>in</strong>g standardization and<br />
quality control of herbal medic<strong>in</strong>es.<br />
Objectives of Research <strong>in</strong><br />
Herbal <strong>Medic<strong>in</strong>e</strong>s<br />
The hallmark of modern medic<strong>in</strong>e is the<br />
scientific approach <strong>in</strong> promot<strong>in</strong>g health,<br />
prevent<strong>in</strong>g diseases and cur<strong>in</strong>g ailments.<br />
Scientific methodology consists of the<br />
follow<strong>in</strong>g approaches:<br />
� Astute observation;<br />
� Formation of hypothesis;<br />
� Experimentation to prove or reject the<br />
hypothesis;<br />
� Acceptance and <strong>in</strong>corporation of the<br />
results of research <strong>in</strong> modern medic<strong>in</strong>e.<br />
S<strong>in</strong>ce most herbal medic<strong>in</strong>es used <strong>in</strong><br />
traditional practices are based on<br />
empiricism, there is a need to separate<br />
chaff from the gra<strong>in</strong> and prove, beyond<br />
reasonable doubt, the efficacy, safety and<br />
cost-effectiveness of herbal medic<strong>in</strong>es. Such<br />
an approach not only enriches modern<br />
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