full report - UCT - Research Report 2011

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238 The faculty also hosts eight of the university’s 29 SARChI Chairs and 21 research groupings or entities that are accredited by the University Research Committee. Three academics linked to the faculty, Professor Bongani Mayosi (Head of Department: Medicine), Professor Heather Zar, and Emeritus Professor Kit Vaughan (with the PantoScanner team at CapeRay Medical, a UCT spin-off company), were honoured this year with 2011/12 National Science and Technology Forum (NSTF)-BHP Billiton Awards for excellence in scientific research, technological innovation, education, capacity building, and communication. A notable achievement in the past year was the increase in the number of publications in peer-reviewed, accredited Departments Department of Anaesthesia Department of Paediatrics and Child Health Department of Clinical Laboratory Science Department of Health and Rehabilitation Sciences Department of Human Biology Department of Medicine Department of Obstetrics and Gynaecology Primary Health Care Directorate Department of Psychiatry and Mental Health School of Public Health and Family Medicine Department of Radiation Medicine Department of Surgery UCT ReseARCh RepORT '11
journals by our faculty, from 846 publications (348.89 units) in 2008 and 931 publications (370.94 units) in 2009, to 1 077 publications (378.07 units) – or 36 percent of UCT’s total) – being published in 2010. This is approximately 70 percent more than the number of publications, as measured by units, achieved five years ago. Publication counts for 2011 are pending but are expected to have increased further. To continue this impressive trajectory, during 2011 the Faculty Research Committee was engaged in developing its strategic plan for research for the period 2012 to 2020, on the basis of widespread consultation and participation from staff across the faculty, following the report from the international experts who conducted an external review of the faculty’s research enterprise in 2010. Some of the external review recommendations have already been implemented, including the strengthening of research governance, increased support for MMed research projects, a 33 percent increase in publication subsidy allocated to departments, and increased investment in the faculty’s core facilities and services. The faculty’s new research strategy for 2012 to 2020, and more importantly, clear plans of action, will be launched in its centenary year. Moving forward, the faculty retains its accountability to the community we serve and continues to apply its research to addressing the burden of disease in our province, country and continent. To meet growing healthcare demands and continue our crucial role in advancing better health for all, the faculty must expand its core function of undergraduate education, postgraduate training, and, importantly, research. We will continue to support the longterm sustainability of existing research units, while working to address priorities identified during the external review: enabling research by further strengthening core facilities and core support services, and encouraging increased research productivity through innovative funding strategies for both established and emerging research groups. To this end, an active search for increasing internal and external funding will be a priority. Looking back on a productive year for the faculty, I extend appreciation to our funders, donors, partners and collaborators who have worked with us during 2011, and who continue to share in the success of our achievements. I also express my sincere gratitude to the staff and students for their dedication to advancing and deepening our research goals and achievements. As we enter our 100 th year, we look forward to translating our successes into significant impacts on the health of the public – locally, nationally and across our continent. PROFESSOR MARIAN JACOBS Dean of the Faculty of Health Sciences FACULTY OF heALTh sCienCes Doctoral graDuations N. Allie (CliNiCAl lAborAtory SCieNCeS) The role of cell specific tumour necrosis factor in the host’s immune response against mycobacterium tuberculosis infection. supervised by Associate Professor M. Jacobs C. ANthoNy (CliNiCAl lAborAtory SCieNCeS) The importance of n-linked glycosylation on the n-domain of angiotensin-i converting enzyme. supervised by Professor E.D. Sturrock and Dr S.L. Schwager r.D. bAllim (humAN biology) The regulation of TBX3 by TBX2 and by the retinoic acid signaling pathway. supervised by Dr S. Prince J. blANCkeNberg (meDiCiNe) Molecular genetics of arrhythmogenic right ventricular cardiomyopathy in South Africa. supervised by Professor B. Mayosi Z. bruwer (CliNiCAl lAborAtory SCieNCeS) An investigation into factors which have an impact on access to and utilisation of the genetic and endoscopic surveillance clinic offered to high-risk members of known Lynch families. supervised by Professor R. Ramesar and Dr M. Futter h. buChANAN (heAlth AND rehAbilitAtioN SCieNCeS) Evidence-based practice in the occupational therapy profession in South Africa and the Western Cape. supervised by Professor J. Jelsma D. Crombie (humAN biology) The role of emotional intelligence in sports performance. supervised by Professor T. Noakes S. DobNer (Surgery) Investigations into the stability of growth factor – induced vasculature and the effects of synthetic biomaterials on heart remodelling after myocardial infarction. supervised by Dr N. Davies r. DomiNgo (CliNiCAl lAborAtory SCieNCeS) Characterisation of the angiotensin-converting enzyme sheddase and synthesis of peptidomimetic inhibitors. supervised by Professor E.D. Sturrock r.g. DouglAS (CliNiCAl lAborAtory SCieNCeS) The significance of active site residues in n-domain selectivity of angiotensin-converting enzyme. supervised by Professor E.D. Sturrock 239
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20 11 University of Cape Town Resea
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2 Our Mission Statement UCT aspires
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4 UCT RESEARCH REPORT '11
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6 New UCT Fellow Professor Vanessa
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8 Professor Hans-Peter Kunzi was on
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10 NRF A-rated researcher Professor
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12 Dr Thomas Scriba, a finalist in
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14 Department of Research and Innov
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16 Research Contracts and Intellect
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18 NSTF-BHP BILLITON 2011/12 WINNER
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20 Research funding is often used a
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22 SA Government Public Entities an
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24 international students at UCT ha
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26 Degree Awards Departmental funds
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28 Source Awards Non-SADC Internati
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30 POSTDOCTORAL RESEARCH FELLOWS (P
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32 Celebrating our new A- and P-rat
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34 Dr David Braun: Researching the
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36 NRF-rated researchers at UCT dur
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38 DST/NRF SARChI CHAIRS AT UCT Ani
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40 the signature themes are grounde
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42 From the lab to the market: cutt
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44 Drug and vaccine discovery given
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46 Testing the waters The Aquatest
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48 Dr George Vicatos, a mechanical
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50 Research themes CLIMATE CHANGE A
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52 Climate change UCT ReseaRCh Repo
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54 UCT launches a co-ordinated assa
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56 signature themes associated with
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58 Research groupings associated wi
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60 DsT/nRF saRChI Chairs associated
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62 astronomy UCT ReseaRCh RepoRT '1
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64 It’s written in the stars: Sou
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66 “Each of the (MeerKAT) project
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68 social and economic relevance UC
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70 The business of integrating rese
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74 Water research UCT ReseaRCh Repo
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76 UCT researchers combine to prote
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78 Research grouping associated wit
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80 Burden of disease UCT ReseaRCh R
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82 A big-picture view to reduce the
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84 signature theme associated with
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90 DsT/NRF saRChI Chairs associated
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92 Computing power UCT ReseaRCh Rep
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94 The many applications of computi
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98 “The HPC node ran its first UC
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100 poverty and economics UCT Resea
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102 Turning the tide on poverty Whe
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104 Research groupings associated w
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106 grants or other social spending
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108 engineering the economy UCT Res
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110 From resources to knowledge: th
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112 UCT’s Minerals to Metals rese
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114 Competence centre associated wi
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118 human biology UCT ReseaRCh Repo
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120 In praise and pursuit of the hu
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122 Research grouping associated wi
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124 physics UCT ReseaRCh RepoRT '11
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126 Solving the mysteries of the Un
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130 humanities footprint UCT ReseaR
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132 Making the case for humanities
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138 Brain behaviour UCT ReseaRCh Re
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140 The science of substance abuse
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144 DsT/NRF saRChI Chairs associate
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146 Urban challenges UCT ReseaRCh R
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148 Creating healthy and resilient
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152 Environment: the Centre for Tra
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154 The Constitution UCT ReseaRCh R
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156 Public values and private right
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160 DsT/NRF saRChI Chairs associate
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162 Research without borders UCT Re
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164 UCT stakes its claim on the int
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166 and must fulfill at least one o
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168 Research support UCT ReseaRCh R
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170 Looking after a new generation
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172 ways of generating new knowledg
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174 Faculty of Engineering & the Bu
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176 profile collaboration network,
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178 lewis, a.e. and naTHOO, J.a. Me
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180 scHOOl sTaTisTics permanent and
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182 governance. In O. Bodin and C.
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184 exhibitions Todeschini, F. 2011
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186 pOsTdOcTOral FellOws dr Mayeli
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Page 268 and 269: 266 Department of clinical laBorato
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288 Mazandu, G.K. and Mulder, N.J.
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290 Roberts, T., Stephens, L.W., Sc
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292 Hermjakob, H. 2011. Dasty3, a W
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294 study that explores the capacit
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296 mS ShAmilA mANie Intensive Care
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298 Jelsma, J.M., Davids, N. and Fe
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300 South Africa’s most important
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302 ASSoCiAte ProFeSSor mArJANNe Se
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304 Dr roSS tuCker RUESSM: Research
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306 Hemmerich, A., van der Merwe, W
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308 O’Connell, K., Posthumus, M.
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310 Annual ISMRM Scientific Meeting
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312 reSeArCh FielDS AND StAFF ASSoC
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314 Develop, evaluate and implement
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316 CoNtACt DetAilS Postal Address:
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318 the AlbertiNA AND wAlter SiSulu
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320 DiviSioN oF Neurology heAD oF D
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322 diseases unit provides inpatien
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324 G., Allwood, B., Dawson, R. and
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326 Gabriels, G.A., Lambert, M.I.,
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328 antiretroviral therapy in South
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330 Are interferon- release assays
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332 Opie, L.H. 2011. Glycaemia and
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334 Cornick, R., Faris, G.F. and Dr
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336 of Serum C-Reactive Protein as
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338 Dr ANNe horAk High risk obstetr
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340 primary health care Directorate
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342 child and adolescent psychiatry
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344 of adverse effect in fetal alco
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346 Stein, D.J., Bandelow, B., Meri
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348 Further, in addition to subsidy
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350 pesticide risk management is st
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352 • Two senior staff members ob
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354 system; human rights issues in
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356 Schuur Hospital, Cape Town, dur
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358 Harris, B., Goudge, J., Ataguba
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360 Mann, g., Thomson, R., Jin, C.,
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362 and Zwarenstein, M. 2011. From
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364 assistant managers (medical phy
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366 contract research staff part-ti
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368 de Boer, R.H., Arrieta, O., Yan
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370 segment surgery, corneal diseas
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372 DiviSioN oF emergeNCy meDiCiNe
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374 students Doctoral 1 master’s
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376 CoNtACt DetAilS Postal Address:
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378 permanent and long term contrac
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380 auxilliary artery injuries. Sou
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382 Van Zyl, L. 2011. Severe bilate
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384 host of the world-renowned Jame
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386 m. mutowo (graDuatE School of B
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388 aSSociatE profESSor JEnnifEr ro
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390 rESEarch fiElDS anD Staff perma
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392 Suleman (eds), Proceedings of S
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394 Steyn and E.M. Villeneuva (eds)
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396 Since 1999 SALDRU has run the a
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398 profESSor anthony Black Develop
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400 mr DaviD (chEn-wEi) tSEng Labou
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402 articles in peer-reviewed Journ
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404 The section is affiliated with
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406 school statistics professors 4
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408 Raubenheimer, H. 2011. Constrai
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410 South African women’s magazin
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412 Africa Can, pp. 371-399. Washin
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414 Faculty of Humanities Dean’s
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416 South African Art in Context Vo
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418 n. mAmmon (EnviRonmEntAl And gE
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420 REsEARch outPut edited books Ok
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422 AssociAtE PRofEssoR lEslEy mARx
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424 Ndlovu, M.W. 2011. The meaning
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426 chapters in books Alexander, J.
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428 Collection, Neu-Ulm/Burlafingen
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430 REsEARch outPut articles in pee
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432 Dance International: Produced a
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434 Mahali, A. 2011. “Piecing tog
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436 PRofEssoR johAn mullER Curricul
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438 peer-reviewed published confere
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440 EmERitus PRofEssoR gEoffREy hug
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442 Schalkwyk, D.J. 2011. The impos
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444 Pissarra, M., Goniwe, T. and Ma
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446 and Cinema in Francophone West
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448 Hambidge, J.H. 2011. Alle grapp
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450 mR. williAm hAuBRich Brass, par
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452 Hofmeyr, H.P. 2011. Il poeta e
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454 Grace, J. 2011. “Concert in t
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456 Liebl, L.B. 2011. Carmina Buran
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458 Van Schalkwyk, A. 2011. Liszt 2
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460 Wanderer, J.R. 2011. On Vice an
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462 Cameron, R.G. and Milne, C. 201
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464 Carr, S.C., Bandawe, C.R., Mart
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466 Department of religious stuDies
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468 Mobilising Religious Health Ass
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470 PRof cARolyn hAmilton National
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472 Department of social DeVelopmen
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474 pedagogics in higher education;
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476 Sitas, A. 2011. The moving blac
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478 Steinberg, J. 2011. A bag of so
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480 AIDS policy, AIDS denialism; AI
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482 Faculty of Science Dean’s rep
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484 in Professor Kevin Naidoo, Prof
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486 m.f. munyololo (Chemistry) New
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488 britton, d.t. And hÄrtinG, m.
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490 emeritus professors professor n
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492 Department of astronomy (Includ
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494 reseArCh output articles in pee
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496 De Blok, W.J.G. 2011. The MeerK
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498 students postdoctoral 4 doctora
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500 February, E.C., Allsopp, N., Sh
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502 Schutz, A., Bond, W.J. and Cram
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504 AssoCiAte professor dAvid W. GA
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506 Cabrera, D.G., Douelle, F., Fen
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508 and Heck cross-coupling reactio
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510 secure data storage on the web.
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512 Kapuire, G. and Blake, E.H. 201
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514 has established itself as a cen
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516 dr Chris lennArd Atmospheric sc
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518 developing world fisheries. Law
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520 reseArCh output edited books Fa
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522 Rowe, C. and Backeberg, N. 2011
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524 dr mArGAret ArChibAld Lecturer;
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526 articles in peer-reviewed Journ
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528 Ellis, G.F.R. 2011. Shear free
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530 Uzan, J., Ellis, G.F.R. and Lar
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532 students post-doctoral 10 docto
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534 Galvao, B., Meggersee, R.L. and
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536 feather disease virus isolates.
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538 dr s. sWArt Southern ocean Biog
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540 Shillington, F.A. 2011. Johann
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542 professor f.e. lubben Physics E
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544 Govender, I., Mangesana, N., Ma
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546 professor GrAhAm bArr Econometr
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548 Newling, J., Varughese, M., Bas
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550 depArtmentAl stAtistiCs permane
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552 Honorary professors professor d
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554 ContACt detAils Tel: +27 21 650
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556 Blattodea), with placement of a
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558 Marchante, H., Freitas, H. and
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560 a description of a new species
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562 Zetlmeisl, C., Hermann, J., Pet
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564 A new generation of university
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566 aCaDemIC DeVeLopment proGramme
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568 Dr howArD PeArCe Senior Lecture
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570 into entrepreneurial ventures:
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572 Centre For InFormatIon LIteraCY
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574 ASSoCIATe ProfeSSor SueLLen ShA
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576 UCT REsEARCH REPORT '11
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