full report - UCT - Research Report 2011

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290 Roberts, T., Stephens, L.W., Scott, C., Urban, M., Sudi, S. and Beighton, P. 2011. Fibrodysplasia ossificans progressiva (FOP) in South Africa: dental implications in 5 cases. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 112(1): 11-18. Roederer, M.W., Sanchez-Giron, F., Kalideen, K., Kudzi, W., McLeod, H.L. and Zhang, W. 2011. Pharmacogenetics and rational drug use around the world. Pharmacogenomics, 12(6): 897-905. Roehrs, S. 2011. Waiting and watching: Malema’s delayed apology and compensation payment and their broader implications. Agenda, 90/25(4): 112-117. Rosario, K., Marinov, M., Stainton, D., Kraberger, S., Wiltshire, E.J., Collings, D.A., Walters, M., Martin, D.P., Breitbart, M. and Varsani, A. 2011. Dragonfly cyclovirus, a novel single-stranded DNA virus discovered in dragonflies (Odonata: Anisoptera). Journal of General Virology, 92: 1302-1308. Rybicki, E.P., Williamson, A.-.L., Meyers, A.E. and Hitzeroth, I.I. 2011. Vaccine farming in Cape Town. Human Vaccines, 7(3): 1-10. Salari, K., Massumi, H., Heydarnejad, J., Pour, A.H. and Varsani, A. 2011. Analysis of Iranian Potato virus S isolates. Virus Genes, 43: 281-288. Salazar, G.A., Jimenez, R.C., Alexander, G., Hermjakob, H., Mulder, N.J. and Blake, E.H. 2011. DAS writeback: A collaborative annotation system. BMC Bioinformatics, 12:143. (8pp) Samuel, C., Whitelaw, A.C., Corcoran, C., Morrow, B., Hsiao, N.M., Zampoli, M. and Zar, H.J. 2011. Improved detection of Pneumocystis jirovecii in upper and lower respiratory tract specimens from children with suspected pneumocystis pneumonia using real-time PCR: a prospective study. BMC Infectious Diseases, 11:329. (6pp) Scott, C., Urban, M., Arendse, R., Dandara, C. and Beighton, P. 2011. Fibrodysplasia Ossificans Progressiva in South AfricaDifficulties in Management in a Developing Country. JCR-Journal of Clinical Rheumatology, 17(1): 37-41. Semegni, J.E., Wamalwa, M., Gaujoux, R., Harkins, G.W., Gray, A. and Martin, D.P. 2011. NASP: a parallel program for identifying evolutionarily conserved nucleic acid secondary structures from nucleotide sequence alignments. Bioinformatics, 27(17): 2443-2445. Shen, Y., Shephard, E.G., Douglass, N., Johnston, N., Adams, C.H., Williamson, C. and Williamson, A.-.L. 2011. A novel candidate HIV vaccine vector based on the replication deficient Capripoxvirus, Lumpy skin disease virus (LSDV). Virology Journal,8:265. (12pp). http://www. virologyj.com/content/8/1/265. Shires, K.L., Shankland, I. and Gerdener, T. 2011. FLT3 ITD Detection: A closer look at the options. Medical Technology SA, 25(2): 39-46. Simabuco, F.M., Asara, J.M., Guerrero, M.C., Libermann, T.A., Zerbini, L.F. and Ventura, A.M. 2011. Structural Analysis of Human Respiratory Syncytial Virus Protein: Identification of Intrinsically Disordered Domains. Brazilian Journal of Microbiology, 42: 340-345. Singh, R., Cadeddu, R.P., Fröbel, J., Wilk, C.M., Bruns, B., Zerbini, L.F., Prenzel, T., Hartwig, S., Brünnert, D., Schroeder, T., Lehr, S., Haas, R. and Czibere, A. 2011. The non-steroidal anti-inflammatory drugs Sulindac sulfide and Diclofenac induce apoptosis and diferentiation in human acute myeloid leukemia cells through an AP-1 dependent pathway. Apoptosis, 16: 889-901. Smith, J., Mowla, S.B. and Prince, S. 2011. Basal transcription of the human TBX3 gene, a key developmental regulator which is overexpressed in several cancers, requires functional NF-Y and Sp1 sites. Gene, 486: 41-46. Smith, J.T., Li, Q., Yap, K.S., Shahab, M., Roseweir, A.K., Millar, R.P. and Clarke, I.J. 2011. Kisspeptin Is Essential for the Full Preovulatory LH Surge and Stimulates GnRH Release from the Isolated Ovine Median Eminence. Neuroendocrinology, 152(3): 1001-1012. Smuts, H., Workman, L.J. and Zar, H.J. 2011. Human rhinovirus infection in young African children with acute wheezing. BMC Infectious Diseases, 11:65. (8pp) Ssemwanga, D., Lyagoba, F., Ndembi, N., Mayanja, B.N., Larke, N., Wang, S., Baalwa, J., Williamson, C., Grosskurth, H. and Kaleebu, P. 2011. Multiple HIV-1 infections with evidence of recombination in heterosexual partnerships in a low risk Rural Clinical Cohort in Uganda. Virology, 411(1): 113-131. Strehlau, R., Martens, L., Coovadia, A., Dandara, C., Norman, J.J., Maisel, J., Kuhn, L. and Abrams, E. 2011. Absence Seizures Associated With Efavirenz Initiation. Pediatric Infectious Disease Journal, 30(11): 1001-1003. Stringer, T., Therrien, B., Hendricks, D.T., Guzgay, H. and Smith, G.S. 2011. Mono- and dinuclear (6-arene) ruthenium(II) benzaldehyde thiosemicarbazone complexes: synthesis, characterization and cytotoxicity. Inorganic Chemistry Communications, 14: 956-960. Stupart, D.J., Goldberg, P.A., Baigrie, R.J., Algar, U. and Ramesar, R.S. 2011. Surgery for colonic cancer in HNPCC: total vs segmental colectomy. Colorectal Disease, 13(12): 1395-1399. UCT ReseARCh RepORT '11
Symons, G., Shean, S., Pietersen, G.E., Van Zyl Smit, R., Pool, L., Davids, M., Willcox, P.A. and Dheda, K. 2011. A historical review of XDR tuberculosis in the Western Cape province of South Africa. SAMJ South African Medical Journal, 101(9): 636-638. Tadokera, R., Meintjes, G., Skolimowska, K.H., Wilkinson, K., Matthews, K., Seldon, R.R., Chegou, N.N., Maartens, G., Rangaka, M.X., Rebe, K., Walzl, G. and Wilkinson, R.J. 2011. Hypercytokinaemia accompanies HIV-tuberculosis immune reconstitution inflammatory syndrome. European Respiratory Journal, 37(5): 1248-1259. Scriba, T.J., Tameris, M.D., Mansoor, N., Smit, E., Van der Merwe, L., Mauff, K.A.L., Hughes, E.J., Moyo, S., Brittain, N., Lawrie, A., Mulenga, H., de Kock, M., Gelderbloem, S., Veldsman, A., Hatherill, M., Geldenhuys, H.D., Hill, A.V.S., Hussey, G.D., Mahomed, H., Hanekom, W.A. and McShane, H. 2011. Dose-Finding Study of the Novel Tuberculosis Vaccine, MVA85a, in Healthy BCG-Vaccinated Infants. Journal of Infectious Diseases, 203: 1832-1843. Tanzer, F.L., Shephard, E.G., Palmer, K.E., Burger, M., Williamson, A.-.L. and Rybicki, E.P. 2011. The porcine circovirus type 1 capsid gene promoter improves antigen expression and immunogenicity in a HIV-1 plasmid vaccine. Virology Journal, 8(51): 8:51. (10pp). http://www. virologyj.com/content/8/1/51. Theron, G., Peter, J., Van Zyl Smit, R., Mishra, H., Streicher, E.M., Murray, S., Dawson, R., Whitelaw, A.C., Hoelscher, M., Sharma, S.K., Pai, M., Warren, R.M. and Dheda, K. 2011. Evaluation of the Xpert MTB/RIF assay for the diagnosis of pulmonary tuberculosis in a high HIV prevalence setting. American Journal of Respiratory and Critical Care Medicine, 184: 132-140. Urban, M., Stewart, C., Ruppelt, T. and Geerts, L.G.T.M. 2011. Effectiveness of prenatal screening for Down syndrome on the basis of maternal age in Cape Town. SAMJ South African Medical Journal, 101(1): 45-48. Valley-Omar, Z., Meyers, A.E., Shephard, E.G., Williamson, A.-.L. and Rybicki, E.P. 2011. Abrogation of contaminating RNA activity in HIV-1 Gag VLPs. Virology Journal, 8: E462. (12pp). www.virologyj.com/content/8/1/462. Van der Sanden, S., van Eek, J., Martin, D.P., van der Avoort, H., Vennema, H. and Koopmans, M. 2011. Detection of recombination breakpoints in the genomes of human enterovirus 71 strains isolated in the Netherlands in. Infection Genetics And Evolution, 11: 886-894. Van Der Ventel, M., Nieuwenhuizen, N., Kirstein, F., Hikuam, C., Jeebhay, M.F., Swoboda, I., Brombacher, F. and Lopata, A.L. 2011. Differential responses to natural and recombinant allergens in a murine model of fish allergy. Molecular Immunology, 48: 637-646. FACULTY OF heALTh sCienCes Van Der Watt, G., Eley, B.S. and Henderson, H.E. 2011. Whole blood mitochondrial DNA depletion in South African HIV-infected children. Journal of Pediatric Biochemistry, 1: 225-232. Van der Watt, P., Ngarande, E. and Leaner, V.D. 2011. Overexpression of Kpn1 and Kpn2 Importin Proteins in Cancer Derives from Deregulated E2F Activity. PLoS One, 6(11): e27723. (10pp) Van der Watt, P. and Leaner, V.D. 2011. The nuclear exporter, Crm1, is regulated by NFY and Sp1 in cancer cells and repressed by p53 in response to DNA damage. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms, 1809: 316-326. Van Kets, V., Liebenberg, L., Wainwright, H.C., Martin, L.J., Gunston, G.D. and Alexander, R.L. 2011. Atherosclerotic lesions in the thoracic aorta: A South African anatomical and histological mortuary study. SAMJ South African Medical Journal, 110: 409-412. Van Rooyen, J., Abratt, V.R., Belrhali, H. and Sewell, B.T. 2011. Crystal Structure of Type III Glutamine Synthetase: Surprising Reversal of the Inter-Ring Interface. Structure, 19: 471 – 483. Van Rooyen, J., Belrhali, H., Abratt, V.R. and Sewell, B.T. 2011. Proteolysis of the type III glutamine synthetase from Bacteroides fragilis causes expedient crystalpacking rearrangements. Acta Crystallographica Section F-Structural Biology and Crystallization Communications, F67358-363. Van Schalkwyk, W., Opie, J.J. and Novitzky, N. 2011. The diagnostic utility of bone marrow biopsies performed for the investigation of fever and/or cytopenias in HIV-infected adults at Groote Schuur Hospital, Western Cape, South Africa. International Journal Of Laboratory Hematology, 33(3): 258-266. Van Zyl-Smit, R., Binder, A.B., Meldau, R., Mishra, H., Semple, P.L., Theron, G., Peter, J., Whitelaw, A.C., Sharma, S.K., Warren, R.M., Bateman, E.D. and Dheda, K. 2011. Comparison of quantitative techniques including Xpert MTB/RIF to evaluate mycobacterial burden. PLoS One, 6(12): e28815. (10pp) Vassall, A., van Kampen, S., Sohn, H., Michael, J.s., John, K.R., den Boon, S., Davis, L.J., Whitelaw, A.C., Nicol, M.P., Gler, M.T., Khaliqov, A., Zamudio, C., Perkins, M.D., Boehme, C. and Cobelens, F. 2011. Rapid diagnosis of tuberculosis with the Xpert MTB/RIF assay in high burden countries: A cost-effectiveness analysis. Plos Medicine, 8(11): e1001120(13). Villaveces, J., Rafael, J.C., Garcia, L.J., Salazar, G.A., Gel, B., Mulder, N.J., Martin, M., Alexander, G. and 291
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20 11 University of Cape Town Resea
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120 In praise and pursuit of the hu
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124 physics UCT ReseaRCh RepoRT '11
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126 Solving the mysteries of the Un
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132 Making the case for humanities
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362 and Zwarenstein, M. 2011. From
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424 Ndlovu, M.W. 2011. The meaning
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442 Schalkwyk, D.J. 2011. The impos
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444 Pissarra, M., Goniwe, T. and Ma
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446 and Cinema in Francophone West
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448 Hambidge, J.H. 2011. Alle grapp
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452 Hofmeyr, H.P. 2011. Il poeta e
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456 Liebl, L.B. 2011. Carmina Buran
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458 Van Schalkwyk, A. 2011. Liszt 2
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462 Cameron, R.G. and Milne, C. 201
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466 Department of religious stuDies
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468 Mobilising Religious Health Ass
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470 PRof cARolyn hAmilton National
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472 Department of social DeVelopmen
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474 pedagogics in higher education;
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476 Sitas, A. 2011. The moving blac
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478 Steinberg, J. 2011. A bag of so
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480 AIDS policy, AIDS denialism; AI
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482 Faculty of Science Dean’s rep
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484 in Professor Kevin Naidoo, Prof
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486 m.f. munyololo (Chemistry) New
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522 Rowe, C. and Backeberg, N. 2011
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524 dr mArGAret ArChibAld Lecturer;
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526 articles in peer-reviewed Journ
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528 Ellis, G.F.R. 2011. Shear free
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530 Uzan, J., Ellis, G.F.R. and Lar
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532 students post-doctoral 10 docto
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534 Galvao, B., Meggersee, R.L. and
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536 feather disease virus isolates.
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538 dr s. sWArt Southern ocean Biog
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540 Shillington, F.A. 2011. Johann
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542 professor f.e. lubben Physics E
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544 Govender, I., Mangesana, N., Ma
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546 professor GrAhAm bArr Econometr
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548 Newling, J., Varughese, M., Bas
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550 depArtmentAl stAtistiCs permane
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552 Honorary professors professor d
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554 ContACt detAils Tel: +27 21 650
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556 Blattodea), with placement of a
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558 Marchante, H., Freitas, H. and
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560 a description of a new species
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562 Zetlmeisl, C., Hermann, J., Pet
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564 A new generation of university
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566 aCaDemIC DeVeLopment proGramme
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568 Dr howArD PeArCe Senior Lecture
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570 into entrepreneurial ventures:
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572 Centre For InFormatIon LIteraCY
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574 ASSoCIATe ProfeSSor SueLLen ShA
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576 UCT REsEARCH REPORT '11
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