full report - UCT - Research Report 2011

Symons, G., Shean, S., Pietersen, G.E., Van Zyl Smit, R.,
Pool, L., Davids, M., Willcox, P.A. and Dheda, K. 2011. A
historical review of XDR tuberculosis in the Western Cape
province of South Africa. SAMJ South African Medical
Journal, 101(9): 636-638.
Tadokera, R., Meintjes, G., Skolimowska, K.H., Wilkinson,
K., Matthews, K., Seldon, R.R., Chegou, N.N., Maartens,
G., Rangaka, M.X., Rebe, K., Walzl, G. and Wilkinson, R.J.
2011. Hypercytokinaemia accompanies HIV-tuberculosis
immune reconstitution inflammatory syndrome. European
Respiratory Journal, 37(5): 1248-1259.
Scriba, T.J., Tameris, M.D., Mansoor, N., Smit, E., Van der
Merwe, L., Mauff, K.A.L., Hughes, E.J., Moyo, S., Brittain,
N., Lawrie, A., Mulenga, H., de Kock, M., Gelderbloem, S.,
Veldsman, A., Hatherill, M., Geldenhuys, H.D., Hill, A.V.S.,
Hussey, G.D., Mahomed, H., Hanekom, W.A. and McShane,
H. 2011. Dose-Finding Study of the Novel Tuberculosis
Vaccine, MVA85a, in Healthy BCG-Vaccinated Infants.
Journal of Infectious Diseases, 203: 1832-1843.
Tanzer, F.L., Shephard, E.G., Palmer, K.E., Burger, M.,
Williamson, A.-.L. and Rybicki, E.P. 2011. The porcine
circovirus type 1 capsid gene promoter improves antigen
expression and immunogenicity in a HIV-1 plasmid
vaccine. Virology Journal, 8(51): 8:51. (10pp). http://www.
virologyj.com/content/8/1/51.
Theron, G., Peter, J., Van Zyl Smit, R., Mishra, H.,
Streicher, E.M., Murray, S., Dawson, R., Whitelaw, A.C.,
Hoelscher, M., Sharma, S.K., Pai, M., Warren, R.M. and
Dheda, K. 2011. Evaluation of the Xpert MTB/RIF assay
for the diagnosis of pulmonary tuberculosis in a high HIV
prevalence setting. American Journal of Respiratory and
Critical Care Medicine, 184: 132-140.
Urban, M., Stewart, C., Ruppelt, T. and Geerts, L.G.T.M.
2011. Effectiveness of prenatal screening for Down
syndrome on the basis of maternal age in Cape Town.
SAMJ South African Medical Journal, 101(1): 45-48.
Valley-Omar, Z., Meyers, A.E., Shephard, E.G., Williamson,
A.-.L. and Rybicki, E.P. 2011. Abrogation of contaminating
RNA activity in HIV-1 Gag VLPs. Virology Journal, 8: E462.
(12pp). www.virologyj.com/content/8/1/462.
Van der Sanden, S., van Eek, J., Martin, D.P., van
der Avoort, H., Vennema, H. and Koopmans, M. 2011.
Detection of recombination breakpoints in the genomes of
human enterovirus 71 strains isolated in the Netherlands
in. Infection Genetics And Evolution, 11: 886-894.
Van Der Ventel, M., Nieuwenhuizen, N., Kirstein, F.,
Hikuam, C., Jeebhay, M.F., Swoboda, I., Brombacher, F.
and Lopata, A.L. 2011. Differential responses to natural
and recombinant allergens in a murine model of fish
allergy. Molecular Immunology, 48: 637-646.
FACULTY OF heALTh sCienCes
Van Der Watt, G., Eley, B.S. and Henderson, H.E. 2011.
Whole blood mitochondrial DNA depletion in South African
HIV-infected children. Journal of Pediatric Biochemistry, 1:
225-232.
Van der Watt, P., Ngarande, E. and Leaner, V.D. 2011.
Overexpression of Kpn1 and Kpn2 Importin Proteins in
Cancer Derives from Deregulated E2F Activity. PLoS One,
6(11): e27723. (10pp)
Van der Watt, P. and Leaner, V.D. 2011. The nuclear
exporter, Crm1, is regulated by NFY and Sp1 in cancer
cells and repressed by p53 in response to DNA damage.
Biochimica et Biophysica Acta-Gene Regulatory
Mechanisms, 1809: 316-326.
Van Kets, V., Liebenberg, L., Wainwright, H.C., Martin, L.J.,
Gunston, G.D. and Alexander, R.L. 2011. Atherosclerotic
lesions in the thoracic aorta: A South African anatomical
and histological mortuary study. SAMJ South African
Medical Journal, 110: 409-412.
Van Rooyen, J., Abratt, V.R., Belrhali, H. and Sewell, B.T.
2011. Crystal Structure of Type III Glutamine Synthetase:
Surprising Reversal of the Inter-Ring Interface. Structure,
19: 471 – 483.
Van Rooyen, J., Belrhali, H., Abratt, V.R. and Sewell, B.T.
2011. Proteolysis of the type III glutamine synthetase
from Bacteroides fragilis causes expedient crystalpacking
rearrangements. Acta Crystallographica Section
F-Structural Biology and Crystallization Communications,
F67358-363.
Van Schalkwyk, W., Opie, J.J. and Novitzky, N. 2011. The
diagnostic utility of bone marrow biopsies performed for
the investigation of fever and/or cytopenias in HIV-infected
adults at Groote Schuur Hospital, Western Cape, South
Africa. International Journal Of Laboratory Hematology,
33(3): 258-266.
Van Zyl-Smit, R., Binder, A.B., Meldau, R., Mishra, H.,
Semple, P.L., Theron, G., Peter, J., Whitelaw, A.C., Sharma,
S.K., Warren, R.M., Bateman, E.D. and Dheda, K. 2011.
Comparison of quantitative techniques including Xpert
MTB/RIF to evaluate mycobacterial burden. PLoS One,
6(12): e28815. (10pp)
Vassall, A., van Kampen, S., Sohn, H., Michael, J.s., John,
K.R., den Boon, S., Davis, L.J., Whitelaw, A.C., Nicol,
M.P., Gler, M.T., Khaliqov, A., Zamudio, C., Perkins, M.D.,
Boehme, C. and Cobelens, F. 2011. Rapid diagnosis of
tuberculosis with the Xpert MTB/RIF assay in high burden
countries: A cost-effectiveness analysis. Plos Medicine,
8(11): e1001120(13).
Villaveces, J., Rafael, J.C., Garcia, L.J., Salazar, G.A.,
Gel, B., Mulder, N.J., Martin, M., Alexander, G. and
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