full report - UCT - Research Report 2011

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284 Danilov, S.M., Gordon, K., Nesterovitch, A.B., Lünsdorf, H., Chen, Z., Castellon, M., Popova, I., Kalinin, S., Mendonca, E., Petukhov, P.A., Schwartz, D.E., Minshall, R.D. and Sturrock, E.D. 2011. An Angiotensin I-Converting Enzyme Mutation (Y465D) Causes a Dramatic Increase in Blood ACE via Accelerated ACE Shedding. PLoS One, 6(10): e25952. (14pp) Davison, G., Novitzky, N. and Abdulla, R. 2011. The clonogenic potential of selected CD34+ cells from patients with MDS appear preserved when tested ex vivo. Leukemia Research, 35: 1200-1204. Day, C., Abrahams, D.A., Lerumo, L., Janse van Rensburg, E., Stone, L., O’rie, T., Pienaar, B., de Kock, M., Kaplan, G., Mahomed, H., Dheda, K. and Hanekom, W.A. 2011. Functional Capacity of Mycobacterium tuberculosis- Specific T Cell Responses in Humans Is Associated with Mycobacterial Load. Journal of Immunology, 187: 2222- 2232. Deveault, C., Billingsley, G., Duncan, J.L., Bin, J., Theal, R., Vincent, A., Fieggen, K., Gerth, C., Noordeh, N., Traboulsi, E.I., Fishman, G.A., Chitayat, D., Knueppel, T., Millan, J.M., Munier, F.L., Kennedy, D., Jacobson, S.G., Innes, A.M., Mitchell, G.A., Boycott, K. and Heon, E. 2011. BBS Genotype-Phenotype Assessment of a Multiethnic Patient Cohort Calls for a Revision of the Disease Definition. Human Mutation, 32(6): 610-619. Domingo, R., Chibale, K. and Sturrock, E.D. 2011. The significance of the C substituent in the selective inhibition of matrix metalloproteinases 1 and 9. Biological Chemistry, 392: 1003-1010. Donald, K., Mathema, H., Thomas, K. and Wilmshurst, J. 2011. Intellectual and Behavioral Functioning in a South African Cohort of Boys with Duchenne Muscular Dystrophy. Journal of Child Neurology, 26(8): 963-969. Dong, Q., Zhang, J., Li, Q., Bracher, J., Hendricks, D.T. and Zhao, X. 2011. Clinical significance of serum expression of GRO in esophageal squamous cell carcinoma. World Journal of Gastroenterology, 17(21): 2658-2662. Dong, Q., Zhang, J., Hendricks, D.T. and Zhao, X. 2011. GRO and its downstream effector EGR1 regulate cisplatininduced apoptosis in WHCO1 cells. Oncology Reports, 25: 1031-1037. Douglas, R., Ehlers, M.R.W. and Sturrock, E.D. 2011. Vasopeptidase Inbibition - Solving the Cardiovascular Puzzle. Drugs of the Future, 36(1): 33-43. Dunn, R.N. and Pretorius, C. 2011. Cervical PEEK cage standalalone fusion-the issue of subsidence. SA Orthopaedic Journal, 10(1): 25-29. Dunn, R.N. 2011. Ethics of billing-determining one’s value. SA Orthopaedic Journal, 10(2): 20-25 Ebrahim, R. and Thilo, L.R. 2011. Kinetic evidence that newly-synthesized endogenous lysosome-associated membrane protein-1 (LAMP-1) first transits early endosomes before it is delivered to lysosomes. Molecular Membrane Biology, 28(4): 227-242. Fauconnier, M., Bourigault, M.L., Meme, S., Szeremeta, F., Palomo, J., Danneels, A., Charron, S., Fick, L., Jacobs, M., Beloeil, J.C., Ryffel, B. and Quesniaux, V. 2011. Protein Kinase C-Theta Is Required for Development of Experimental Cerebral Malaria. American Journal of Pathology, 178(1): 212-221. Faure, A., Seoighe, C. and Mulder, N.J. 2011. Investigating the effect of paralogs on microarray gene-set analysis. BMC Bioinformatics, 12:29. (14pp) Fayemiwo, S., Muller, E., Gumede, L. and Lewis, D.A. 2011. Plasmid-Mediated Penicillin and Tetracycline Resistance Among Neisseria gonorrhoeae Isolates in South Africa: Prevalence, Detection and Typing Using a Novel Molecular Assay. Sexually Transmitted Diseases, 38(4): 329-333. Firnhaber, C., Sello, M., Maskew, M., Williams, S., Schulze, D., Williamson, A.-.L., Allan, B.R. and Lewis, D. 2011. Human papillomavirus types in HIV seropositive men with penile warts in Johannesburg, South Africa. International Journal of Std & Aids, 22: 107-109. Fortgens, P. and Pillay, T. 2011. Pseudohyponatremia Revisited A Modern-Day Pitfall. Archives of Pathology & Laboratory Medicine, 135: 516-519. Fouche, G., Nieuwenhuizen, N., Maharaj, V., van Rooyen, S., Harding, N., Nthambeleni, R., Jayakumar, J., Kirstein, F., Emedi, B. and Meoni, P. 2011. Investigation of in vitro and in vivo anti-asthmatic properties of Siphonochilus aethiopicus. Journal of Ethnopharmacology, 133: 843-849. Frost, M., Krige, J.E.J., Bornman, P.C., Panieri, E., Beningfield, S.J. and Wainwright, H.C. 2011. Solid pseudopapillary epithelial neoplasm - a rare but curable pancreatic tumour in young women. South African Journal of Surgery, 49(2): 75-81. Garrett, B. and Dunn, R.N. 2011. Surgery for myelopathy in spinal deformity. SA Orthopaedic Journal, 10(1): 30-34. Gasse, P., Riteau, N., Vacher, R., Charron, S., Fick, L. and Ryffel, B. 2011. IL-1 and IL-23 mediate early IL-17A production in pulmonary inflammation leading to late fibrosis. PLoS One, 6(8). (e23185): 1-12. George, J.T., Veldhuis, J., Roseweir, A.K., Newton, C., Faccenda, E., Millar, R.P. and Anderson, R.A. 2011. UCT ReseARCh RepORT '11
Kisspeptin-10 Is a Potent Stimulator of LH and Increases Pulse Frequency in Men. Journal of Clinical Endocrinology and Metabolism, 96(8): E1228 - E1236. Glennie, S.J., Sepako, E. and Miles, D.J.C. 2011. Impaired CD4 T cell memory response to streptococcus pneumoniae precedes CD4 T cell depletion in HIV-infected Malawian adults. PLoS One, 6(9). (e25610): 1-10. Goldsmith, D.B., Crosti, G., Dwivedi, B., McDaniel, L.D., Varsani, A., Suttle, C.A., Weinbauer, M.G., Sandaa, R.A. and Breitbart, M. 2011. Development of phoH as a Novel Signature Gene for Assessing Marine Phage Diversity. Applied and Environmental Microbiology, 77(21): 7730- 7739. Govender, N., Patel, J., van Wyk, M., Chiller, T.M., Lockhart, S.R., Vasaikar, S., Wasserman, E., Hoffmann, R., Zietman, I., Whitelaw, A.C., Hoosen, A., Lekalakala, R., Perovic, O., Cohen, C., Sooka, A., von Gottberg, A., Elliot, G.E., Nchabeleng, M., Olivier, B., Sithole, S., Schrag, S., de Gouveia, L., Frean, J. and Keddy, K. 2011. Trends in antifungal drug susceptibility of cryptocossus noeformans isolates obtained through population-based surveillance in South Africa in 2002-2003 and 2007-2008. Antimicrobial Agents and Chemotherapy, 55(6): 2606-2611. Gray, E.S., Madiga, M.C., Hermanus, T., Moore, P.L., Wibmer, C.K., Tumba, N.L., Werner, L., Mlisana, K., Sibeko, S., Williamson, C., Abdool Karim, S. and Morris, L. 2011. The Neutralization Breadth of HIV-1 Develops Incrementally over Four Years and Is Associated with CD4 T Cell Decline and High Viral Load during Acute Infection. Journal of Virology, 85(10): 4828-4840. Guler, R., Parihar, S., Spohn, G., Johansen, P., Brombacher, F. and Bachmann, M.F. 2011. Blocking IL-1 but not IL-1 increases susceptibility to chronic Mycobacterium tuberculosis infection in mice. Vaccine, 29: 1339-1346. Guler, R., Afshar, M., Arendse, B., Parihar, S., Revazbreton, M., Leitges, M., Schwegmann, A. and Brombacher, F. 2011. PKC regulates IL-12p40/p70 production by macrophages and dendritic cells, driving a type 1 healer phenotype in cutaneous leishmaniasis. European Journal of Immunology, 41(3): 706-715. Gumbi, P., Jaumdally, S.Z., Salkinder, A.L., Burgers, W., Mkhize, N., Hanekom, W.A., Coetzee, D.J., Williamson, A.-.L. and Passmore, J.S. 2011. CD4 T Cell Depletion at the Cervix during HIV Infection Is Associated with Accumulation of Terminally Differentiated T Cells. Journal of Virology, 85(24): 13333-13341. Haarburger, D. and Pillay, T.S. 2011. Historical perspectives in diagnostic clinical pathology:development of the pregnancy test. Journal of Clinical Pathology, 64(6): 546-548. FACULTY OF heALTh sCienCes Hadfield, J., Martin, D.P., Stainton, D., Kraberger, S., Owor, B.E., Shepherd, D.N., Lakay, F., Markham, P.G., Greber, R.S., Briddon, R. and Varsani, A. 2011. Bromus catharticus striate mosaic virus: a new mastrevirus infecting Bromus catharticus from Australia. Archives of Virology, 156: 335-341. Hadfield, J., Linderme, D., Shepherd, D.N., Bezuidenhout, M.E., Lefeuvre, P., Martin, D.P. and Varsani, A. 2011. complete genome sequence of a dahlia common mosaic virus isolate from New Zealand. Archives of Virology, 156: 2297-2301. Harris, T., Meyer, E., Lubbe, D., Smit, W. and Walker, C. 2011. Malignant proliferating trichilemmal tumor involving the sinuses. Ent-Ear Nose & Throat Journal, 90(7): E5-8. Hemelaar, J., Gouws, E., GHYS, P.D., WHO/UNAIDS Network for HIV Isolation and Characterisation, , Osmanov, S., Williamson, C., Bredell, H. and Stewart, D. 2011. Global trends in molecular epidemiology of HIV-1 during 2000 - 2007. AIDS, 25(5): 679-689. Hendricks, M., Davidson, A., Pillay, K., Desai, F. and Millar, A.J.W. 2011. Carboplatin-Based Chemotherapy and Surgery: A Cost Effective Treatment Strategy for Malignant Extracranial Germ Cell Tumours in the Developing World. Pediatric Blood & Cancer, 57: 172-174. Hiller, N.L., Eutsey, R.A., Powell, E., Earl, J.P., Janto, B., Martin, D.P., Dawid, S., Ahmed, A., Longwell, M.J., Dahlgren, M.E., Ezzo, S., Tettelin, H., Daugherty, S.C., Mitchell, T.J., Hillaman, T.A., buchinsky, F.J., Tomasz, A., De Lencastre, H., Sa-Leao, R., Post, C.J., Hu, F.Z. and Ehrlich, G.D. 2011. differences in genotype and virulence among four multidrugresistant strptococcus pneumoniae isolates belonging to the PMEN1 clone. PLoS One, 6(12): e28850. (13pp) Hitchins, M.P., Owens, S., Kwok, C.-.T., Godsmark, G., Algar, U. and Ramesar, R.S. 2011. Identification of new cases of early-onset colorectal cancer with an MLH1 epimutation in an ethnically diverse South African cohort. Clinical Genetics, 80: 428-434. Hong, H.A., Loubser, A.S., de Assis Rosa, D., Naranbhai, V., Carr, W., Paximadis, M., Lewis, D., Tiemessen, C.T. and Gray, C. 2011. Killer-cell immunoglobulin-like receptor genotyping and HLA killer- cell immunoglobulin-like receptor-ligand identification by real time polymerase chain reaction. Tissue Antigens, 78(3): 185-194. Horsnell, W., Vira, A., Kirstein, F., Mearns, H., Hoving, J., Cutler, A., Dewals, B., Myburgh, E., Kimberg, M., Arendse, B., White, N., Lopata, A.L., Burger, P.E. and Brombacher, F. 2011. IL-4Ra-responsive smooth muscle cells contribute to initial TH2 immunity and pulmonary pathology in Nippostrongylis Brasiliensis infections. Mucosal Immunology, 4(1): 83-92. 285
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20 11 University of Cape Town Resea
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2 Our Mission Statement UCT aspires
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4 UCT RESEARCH REPORT '11
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12 Dr Thomas Scriba, a finalist in
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32 Celebrating our new A- and P-rat
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132 Making the case for humanities
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162 Research without borders UCT Re
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168 Research support UCT ReseaRCh R
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184 exhibitions Todeschini, F. 2011
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214 Faculty of Law Dean’s report
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342 child and adolescent psychiatry
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350 pesticide risk management is st
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360 Mann, g., Thomson, R., Jin, C.,
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362 and Zwarenstein, M. 2011. From
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366 contract research staff part-ti
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368 de Boer, R.H., Arrieta, O., Yan
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374 students Doctoral 1 master’s
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378 permanent and long term contrac
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406 school statistics professors 4
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408 Raubenheimer, H. 2011. Constrai
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410 South African women’s magazin
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412 Africa Can, pp. 371-399. Washin
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414 Faculty of Humanities Dean’s
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416 South African Art in Context Vo
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420 REsEARch outPut edited books Ok
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424 Ndlovu, M.W. 2011. The meaning
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426 chapters in books Alexander, J.
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428 Collection, Neu-Ulm/Burlafingen
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430 REsEARch outPut articles in pee
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432 Dance International: Produced a
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434 Mahali, A. 2011. “Piecing tog
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436 PRofEssoR johAn mullER Curricul
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438 peer-reviewed published confere
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440 EmERitus PRofEssoR gEoffREy hug
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442 Schalkwyk, D.J. 2011. The impos
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444 Pissarra, M., Goniwe, T. and Ma
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446 and Cinema in Francophone West
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448 Hambidge, J.H. 2011. Alle grapp
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450 mR. williAm hAuBRich Brass, par
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452 Hofmeyr, H.P. 2011. Il poeta e
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454 Grace, J. 2011. “Concert in t
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456 Liebl, L.B. 2011. Carmina Buran
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458 Van Schalkwyk, A. 2011. Liszt 2
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460 Wanderer, J.R. 2011. On Vice an
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462 Cameron, R.G. and Milne, C. 201
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464 Carr, S.C., Bandawe, C.R., Mart
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466 Department of religious stuDies
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468 Mobilising Religious Health Ass
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470 PRof cARolyn hAmilton National
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472 Department of social DeVelopmen
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474 pedagogics in higher education;
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476 Sitas, A. 2011. The moving blac
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478 Steinberg, J. 2011. A bag of so
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480 AIDS policy, AIDS denialism; AI
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482 Faculty of Science Dean’s rep
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484 in Professor Kevin Naidoo, Prof
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486 m.f. munyololo (Chemistry) New
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488 britton, d.t. And hÄrtinG, m.
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496 De Blok, W.J.G. 2011. The MeerK
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498 students postdoctoral 4 doctora
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500 February, E.C., Allsopp, N., Sh
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502 Schutz, A., Bond, W.J. and Cram
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504 AssoCiAte professor dAvid W. GA
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506 Cabrera, D.G., Douelle, F., Fen
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508 and Heck cross-coupling reactio
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510 secure data storage on the web.
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512 Kapuire, G. and Blake, E.H. 201
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514 has established itself as a cen
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516 dr Chris lennArd Atmospheric sc
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518 developing world fisheries. Law
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520 reseArCh output edited books Fa
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522 Rowe, C. and Backeberg, N. 2011
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524 dr mArGAret ArChibAld Lecturer;
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526 articles in peer-reviewed Journ
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528 Ellis, G.F.R. 2011. Shear free
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530 Uzan, J., Ellis, G.F.R. and Lar
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532 students post-doctoral 10 docto
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534 Galvao, B., Meggersee, R.L. and
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536 feather disease virus isolates.
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538 dr s. sWArt Southern ocean Biog
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540 Shillington, F.A. 2011. Johann
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542 professor f.e. lubben Physics E
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544 Govender, I., Mangesana, N., Ma
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546 professor GrAhAm bArr Econometr
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548 Newling, J., Varughese, M., Bas
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550 depArtmentAl stAtistiCs permane
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552 Honorary professors professor d
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554 ContACt detAils Tel: +27 21 650
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556 Blattodea), with placement of a
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558 Marchante, H., Freitas, H. and
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560 a description of a new species
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562 Zetlmeisl, C., Hermann, J., Pet
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564 A new generation of university
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566 aCaDemIC DeVeLopment proGramme
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568 Dr howArD PeArCe Senior Lecture
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570 into entrepreneurial ventures:
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572 Centre For InFormatIon LIteraCY
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574 ASSoCIATe ProfeSSor SueLLen ShA
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576 UCT REsEARCH REPORT '11
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