full report - UCT - Research Report 2011

dr boris-mArKo KuKoveC
Solid-state studies of large supramolecular assemblies
and metal-organic frameworks
dr AmAn mAhAJAn
Synthesis of novel antimalarial molecules using various
drug based pharmacophores
dr ClAire le mAnACh
Hit to lead and lead optimization medicinal chemistry
progression of antimalarial hits.
dr stefAn louW
Synthesis of novel artemisinin hybrid anti-malarial drugs.
dr Jestin mAndumpAl
Development of coarse grain molecular dynamics software
for protein folding
dr mAiA meurillon
New generation of combined drugs to fight Tuberculosis.
dr GrACe muGumbAte
Application of in silico Tools to the discovery of novel antiinfective
agents.
dr rAJni shArmA
Synthesis of N domain selective ACE inhibitors.
dr CAndiCe soAres de melo
New generation of combined drugs to fight tuberculosis
dr tAKAlAni theKA
Investigation of the effects of ingestion of carbohydrates
sweeteners (glucose, maltitol, lycasin HBC) on kidney
stone risk factors in black and white South Africans
dr KArl WilKinson
Acceleration of GAMESS-UK for graphical processing
units reaction mechanism of the CBHI cellulase from
T.Reesei
dr yAssir younis AdAm
Hit to Lead and Lead Optimization Medicinal Chemistry
Progression of Antimalarial Hits
ContACt detAils
Tel: +27 21 650 2446
Fax: +27 21 650 5195
e-mail: shanaaz.manie@uct.ac.za
web: http://www.uct.ac.za/depts/cem
faCUlTy of sCIeNCe
reseArCh output
chapters in books
Egan, T.J. 2011. Biomimetic approaches to understanding
the mechanism of haemozoin formation. In L. Pramatarova
(ed.), On Biomimetics, pp. 373-394. Rijeka: InTech Open
Access Publisher. ISBN 978-953-307-271-5.
Hutton, A.T. 2011. Nomenclature of organometallic
compounds. In G.J. Leigh (ed.), Principles of Chemical
Nomenclature, pp. 109-132. Cambridge, UK: RCS (Royal
Society of Chemistry). ISBN 9781849730075.
articles in peer-reviewed Journals
André, V., Hardeman, A., Halasz, I., Stein, R.S., Jackson,
G.J., Reid, D.G., Duer, M.J., Curfs, C., Duarte, M.T. and
Friščić, T. 2011, Mechanosynthesis of the metallodrug
bismuth subsalicylate from Bi 2 O 3 and structure of bismuth
salicylate without auxiliary organic ligands. Angewandte
Chemie International Edition, 50: 7858–7861.
Antonels, N.C., Moss, J.R. and Smith, G.S. 2011,
Hydroformylation activity of multinuclear rhodium
complexes coordinated to dendritic iminopyridyl and
iminophosphine scaffolds. Journal of Organometallic
Chemistry, 696: 2003-2007.
Barnett, C.B., Wilkinson, K.A. and Naidoo, K.J. 2011,
Molecular details from computational reaction dynamics
for the cellobiohydrolase I glycosylation reaction. Journal
of the American Chemical Society, 133: 19474-19482.
Báthori, N.B., Lemmerer, A., Venter, G.A., Bourne, S.A.
and Caira, M.R. 2011. Pharmaceutical co-crystals with
isonicotinamide-vitamin B3, clofibric acid, and diclofenacand
two isonicotinamide hydrates. Crystal Growth &
Design, 11: 75-87.
Báthori, N.B., Nassimbeni, L.R. and Oliver, C.L. 2011,
Quininium mandelates – a systematic study of chiral
discrimination in crystals of diastereomeric salts. Chemical
Communications, 47: 2670-2672.
Boscaino, A. and Naidoo, K.J. 2011. The extent of
conformational rigidity determines hydration in nonaromatic
hexacyclic systems. Journal of Physical Chemistry B, 115:
2608-2616.
Bourne, S.A., Corin, K., Cruickshank, D.L., Davson, J.,
Nassimbeni, L.R., Su, H. and Weber, E. 2011. Enclathration
of bases by a fluorenyl host: structure, stability and
selectivity. New Journal of Chemistry, 35: 1556-1561.
Burrows, J.N., Chibale, K., and Wells, T.N.C. 2011. The state
of the art in anti-malarial drug discovery and development,
Current Topics in Medicinal Chemistry, 11:1226-1254.
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