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Universlty of Manitoba, ln Partîal Fulfiìlment - MSpace at the ...

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5<br />

1.5.1 SÞlri¿i B_!ll i dê Occúl rå ând Cysr¡ca<br />

<strong>ln</strong> spina blfîda occulta <strong>the</strong>re ls no open neural lesion,but ro_<br />

en tgenog rans revda I a defect <strong>of</strong> or¡e or more spinous processes or raminae.<br />

The site <strong>of</strong> this bony defect may occasionar ry be marked by abrrormar ities<br />

<strong>of</strong> overlying skin, such as pigmented or. hairy p<strong>at</strong>ches. Though <strong>of</strong>ten<br />

undetected, spína bifida occulta is sometimes accompanied by symptoms<br />

suggesting ínvolvement <strong>of</strong> <strong>the</strong> spinal cord or cauda equina. This could be<br />

caused by ê tight filum terminale, fibrous bands, ¡ntr<strong>at</strong>hecal I ipomas,<br />

or frank myelodysplasia (¡ames and Lassman, ,|967). The symptomless and<br />

symptom<strong>at</strong>ic forms <strong>of</strong> spina bífida occulta may represent two distinct<br />

leslons, <strong>the</strong> former being prima,r.iry a skeretar defect and <strong>the</strong> r<strong>at</strong>ter<br />

secondary to cord or cauda equ¡na defects,<br />

By contrast, ân external ly visible defect is called a spina bifida<br />

manífesta, or apertâ, or cystica (if cystíc). Several types may be distínguished.<br />

I.5.2 Men!!rgoce I e<br />

A meningocele invorves defects <strong>of</strong> severar neurar arches wrth herní<strong>at</strong>ion<br />

<strong>of</strong> meninges but not <strong>of</strong> neural tissue, though <strong>the</strong> underlying cord may be<br />

dysplastíc. For this reason a meningocete cannot always be diagnosed<br />

w¡th certa¡nty, and may prove on explor<strong>at</strong>ion to be myelocele (Laurence,<br />

1964',).<br />

1,5.3. Myelomeningocele<br />

An open lesion consisting <strong>of</strong> neural tissue, accumul<strong>at</strong>ed fluld,<br />

abnormal vasular tíssue, and a variable amount <strong>of</strong> epi<strong>the</strong>l íumrwith <strong>the</strong><br />

loss <strong>of</strong> several neural arches is tradítionar ry calred a myeromeningocere<br />

(fig.3 ¡. However, it is now bel ieved th<strong>at</strong> <strong>the</strong> tesion origin<strong>at</strong>es as a

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