Universlty of Manitoba, ln Partîal Fulfiìlment - MSpace at the ...

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2,4.10 lnfect ion
FInally, some of thè earlier authors such as Brouwer (1916) conãidereC
that the marked disturbance of neural tissue in anencephaly might be
due to embryonic infectionrcausing an extensive encephalomyel itis.
2.lt.11 Surlma rL
Many of these conflicting hypotheses are based on the study of
establ ished Iesions in human specímens collected at random. Assessment
of their validity requíres further stud¡es of early human embryos, and
experimental studies of the development of dysraphism in a range of
animal ¡nodels.