Universlty of Manitoba, ln Partîal Fulfiìlment - MSpace at the ...

3t8
Figures fl:4-127 ' demons t ra te the ratios. in the four categorîes of
enbryos, distinguishi.ng between regions with and w¡thout a neural lesion
in affected embryos. The ratlos are highest ìn the control embryos and
sltghtly lower in the experimental embryos with no defects. l,,tyeloschisis
is associated w¡th a definite reductîon ln rptios,with no suggestion of
neural lrovergrowtht' before or after the stages of normar neural crosure.
All embryos wíth nryelodysplasia show a marked reduction of ratlos. ïhere
is no obvious difference ín ratio between an affected and an adjacent
unaffected region in either myeloschlsís or myelodysplasia, implying
that the neuraì tube adjacent to a leslon shows a similar reduction in size.^
Statistical analysis of the data in Tables 59-66 was restricred to
embryos of Stages 16-20, to provide a comparable distribution of Stages
within the four categoríes. The vatues for the mean notochord area were
f¡rst exam¡ned to test the assumption of uniform notochord s¡ze. An
analysls of varíance showed no signifícant differences in mean notochord
area between the four categoríes in both Regions C and D (Tables .59 ê 60).
TABLE 59A.MEAN NOTOCHORD AREA IN REGION D
Ca tegory Number l''lean S.D. s.D.H.
Cont ro I s
Norma I Exptls.
l4yeloschisís
llyelodysplas la
Totâ I
14
10
1t
5
4o
2985.9
2960.6
2524.\
2989,1
2853.1
1027.3 274.5
980.7 310.t
875.1 263.8
t017,9 455.2
958.4 15t..5