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32 American Society for Laser Medicine and Surgery Abstracts
eyebrow position (85%), midface laxity (81%), jawline definition
(77%), mentolabial folds (68%), infraorbital folds and wrinkles
(64%), cervicomental angle (62%), and nasolabial folds (44%).
Assessment at 6 and 9 months revealed that mid- and lower face
improvement lasted longer than the upper third of the face. Other
than slight transient erythema and edema immediately posttreatment,
generally, there were no major adverse effects noticed.
There were three cases of linear erythematous papules on the
neck which lasted 2–4 weeks. Slight infraorbital nerve palsy was
observed in two subjects. Distressful scalp paresthesia developed
in one subject. All neurologic symptoms resolved spontaneously
within a month.
Conclusion: The micro-focused ultrasound technique is a safe
and effective treatment for lifting and tightening facial soft tissue
in Koreans. Our study showed that in Korean subjects, treatment
of the mid- and lower face showed more patients’ satisfaction and
longer-lasting effects than upper face treatment.
#99
CLINICAL STUDY OF TRANSCUTANEOUS
FOCUSED ULTRASOUND FOR LOWER FACIAL
AND SUBMENTAL SKIN TIGHTENING IN ASIANS
Nicola P.Y. Chan, Carol S. Yu, Johnny C.Y. Chan,
Samantha S. Shek, Henry H.L. Chan
The University of Hong Kong; Eye Institute, Hong Kong, China
Background: The objective of this study was to determine the
clinical efficacy of a focused ultrasound device for the treatment of
lower facial and submental skin laxity in Asians.
Study: Each patient received one treatment with the
transcutaneous focused ultrasound device. Two transducers
(7.5 MHz, 3.0 mm depth; 4.0 MHz, 4.5 mm depth) were used to
deliver two passes of microthermal areas of coagulation over the
lower facial and submental regions at two different depths.
Standardized photos and three-dimensional images were taken
with the Canfield Visia CR and Vectra systems 1 , respectively, at
baseline, 1 month and 3 months post-treatment. They assessed by
two independent physicians.
Results: Sixteen Chinese patients were included. Erythema and
edema were the only temporary adverse effects, which resolved by
1 month. Preliminary objective assessment of standardized photos
showed statistically significant improvement for skin laxity along
the jawline (P ¼ 0.046), and cheek (P ¼ 0.008) at last follow-up. The
degree of improvement was graded as slight to moderate. Vectra 3D
images showed positive skin tightening in submental region.
Conclusion: The dual-plane approach of energy delivery with
transcutaneous high intensity focused ultrasound appeared
effective for lower facial and submental skin laxity in Asians.
Further studies to optimize treatment parameters may enhance
clinical outcomes.
#100
CLINICAL AND HISTOPATHOLOGICAL
EVALUATION OF A NEW NON-INVASIVE BODY
CONTOURING DEVICE COMBINING HIGH
POWER BIPOLAR RADIOFREQUENCY,
INFRARED LIGHT, NEGATIVE PRESSURE AND
MECHANICAL TISSUE MANIPULATION
Hema Sundaram, Jason N. Pozner
Sundaram Dermatology, Cosmetic & Laser Surgery, Fairfax, VA;
Sanctuary Plastic Surgery, Boca Raton, FL
Background: The combination of externally applied bipolar
radiofrequency (RF), infrared light (IR), negative pressure and
mechanical tissue manipulation has been shown to be safe and
efficacious for temporary circumferential reduction and cellulite
improvement. The bipolar RF allows for a reduction in optical
energy applied to the skin. Furthermore, bipolar RF is not
preferentially absorbed by melanin and thus has potential utility
in treating all Fitzpatrick skin phototypes. It was hypothesized
that increasing the power of the bipolar RF would enhance
treatment efficacy and might allow reduction in the duration and/
or number of treatment sessions required.
Study: In this prospective study, patients received one treatment
per week over 6 weeks to one thigh while the non-treated thigh
served as the control. Patients were followed for several months
post-completion of the treatment protocol. Thigh circumferences
were measured and baseline to post treatment comparisons were
made. Thigh circumference reductions were compared between
the treated and non-treated thighs. Safety issues and treatmentemergent
adverse effects were monitored throughout the study.
Results: There was a significant difference in mean
circumferential reduction from baseline to post 6 treatments
between the treated and the non-treated thighs. The incremental
reduction in thigh circumference appeared as soon as 2 weeks
from the beginning of treatment and occurred exclusively in the
treated thighs. Overall improvement in body contour was clearly
noticeable on comparison of the before and after photographs. The
use of high power bipolar RF was well tolerated and was not
associated with adverse events or complications.
Conclusion: External application of high power (200 W) RF energy
combined with IR, negative pressure and tissue manipulation
appears to be a safe and efficient modality for temporary
circumferential reduction and body contouring. Histopathological
correlation suggests that the underlying mechanism of action is
reduction in the hypodermal adipose tissue volume via confined
thermal targeting.
#102
COMPARISON OF FRACTIONAL ER:YAG AND CO2 LASERS IN RESURFACING OF ATROPHIC ACNE
SCARS IN ASIANS
Woraphong Manuskiatti, Thanawan Iamphonrat,
Rungsima Wanitphakdeedecha, Sasima Eimpunth
Siriraj Hospital, Mahidol University, Bangkok, Thailand
Background: Ablative fractional lasers including fractional
Er:YAG and CO2 lasers have recently been introduced to address
some limitations of nonablative fractional lasers. There has been
very little evidence on the comparative efficacy and safety of these
two laser systems, especially in dark-skinned patients who inherit
higher risk of adverse effects following ablative laser treatment.
The aim of the present study was to compare the efficacy and
safety of fractional Er:YAG and CO2 lasers in the treatment of
atrophic acne scars in Asian individuals.
Study: This is a split-face, single-blind, controlled, comparison
study. Twenty-four Thai subjects with atrophic acne scars were
randomly treated using a fractional Er:YAG laser on one side of the
face and a fractional CO2 laser on the other side. Each subject
received with two treatments at 2 months apart. Objective
(ultraviolet A-light video camera) and subjective (clinical evaluation
by two blinded dermatologists) assessments were obtained at
baseline and at 1, 3, and 6 months after the 2nd treatment. The
assessment of pain score, recovery time, side effects, and patient
satisfaction were recorded at every follow-up visit.