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Presidential Greeting - American Society for Laser Medicine and ...

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Wounds were treated using PCRB <strong>and</strong> photoradiated or photoradiated alone. Composite dressing-treated wounds<br />

received 1cm x1cm PCRB wafers, applied by excising Tegaderm TM<br />

overlying the ulcer, placing PCRB over the<br />

wound <strong>and</strong> covering the wound with Tegaderm TM<br />

. Wounds were irradiated at 450nm (350mW, 1cm spot diameter,<br />

15min) using a diode laser 10min after dressing placement daily (0, 1, 2, or 3 treatments). Control wounds received<br />

neither PCRB nor photoradiation. Wounds were cultured daily. Animals were euthanized on day 7 <strong>and</strong> quantitative<br />

bacterial counts (CFU/g tissue) were determined. Results: PCRB plus photoradiation resulted in statistically<br />

significant 2-3 log reduction in bacterial counts (p

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