Presidential Greeting - American Society for Laser Medicine and ...

34 American Society for Laser Medicine and Surgery Abstracts
0.175 milliseconds, 10% coverage—Fotona Dynamis XS) and 25
lesions were treated with a CO 2 fractional laser (0.300 mm spot,
14 W, 500–900 dwell depth—DEKA SmartXide Dot). Ten percent
5-ALA liposome gel under polyurethane occlusion was applied on
all lesion and left for 6 hours. 635 nm LED irradiation (Omnilux)
was finally performed (4\ 0 –20\ 0 pause–14 m\ 0 ). Blind clinical
evaluation at 7–30–60–90–180 days was performed.
Results: Both lesion grouls required an average of 1.5 treatments
to achieve complete eradication. Maximal post-op localized pain
was reported 24–48 hours after the procedure. No scars and/or
infections were observed. Two percent transitory PIH was
observed (two Er:YAG and two CO 2 treated patients). No clinical
recurrences were observed after 180 days.
Conclusion: Thermo-fractional PDT appears to be a very
promising combined technique to treat recalcitrant HPV
infections. No significant differences were observed between
Er:YAG and CO 2 fractional trans-stratum corneum penetration
enhancement of 5-ALA liposome gel as far as clinical results are
concerned. More studies are needed to optimize all different steps
of this innovative treatment approach.
#106
308 NM EXCIMER LASER TREATMENT OF
PALMOPLANTAR PSORIASIS
David Goldberg, Nathalie Dietrich-Comte,
Mussarrat Hussain
Skin Laser & Surgery Specialists of NY and NJ, New York, NY
Background: Palmoplantar psoriasis is difficult to treat and
often recalcitrant to traditional therapies such as topical
corticosteroids. Since the excimer laser can selectively treat
psoriatic plaques with higher fluences than is tolerated with
traditional phototherapy, it could be a therapeutic modality for
the thicker skin on the palms and soles. We undertook a study to
evaluate the safety and efficacy of the 308 nm excimer for the
treatment of psoriasis involving the hands and feet.
Study: A total of thirty male and female subjects between the
ages of 18–75 years with mild to severe psoriasis involving the
palms and soles were treated. All subjects discontinued all other
treatments for 4 weeks prior to starting the study. Subjects
received up to 16 laser treatments over the course of 3 months
with a 308 nm excimer laser. Treatment parameters (400–600 mJ/
cm 2 ) were determined by the severity of disease. Treatments were
performed biweekly. Clearance was evaluated by the PASI scale.
Results: A mean number of 11 sessions (from 7 to 14) was
provided to each subject. By the 5th treatment, all subjects
showed improvement in the PASI score. At the end of treatments,
all subjects showed improvement between 50% and 100% as
evidenced by decreased scale, decreased erythema, and flattened
plaques. No relapse was detected at 3-month post-treatment
follow-up. Relapses were seen in 60% of subjects at 6 months after
treatment.
Conclusion: The 308 nm excimer laser is a treatment option for
palmar–plantar psoriasis.
#107
STUDY OF EFFICACY AND TOLERABILITY
MONOCHROMATIC EXCIMER LIGHT IN
TREATMENT OF VITILIGO
Niteen Dhepe, Tushar Kshirsagar, Ashok Naik,
Vaishali Phadke
Pune, India
Background: To study the efficacy and the safety of the
monochromatic excimer light (MEL) in the treatment of vitiligo.
To make comparison in efficacy between the two treatment
frequencies of monochromatic excimer light in treatment of
vitiligo. To evaluate the safety of the once weekly and twice
weekly regimens of the monochromatic excimer light in treatment
of vitiligo.
Study: Eighty-eight patches from 16 patients of bilateral
symmetrical vitiligo were selected for the treatment with
monochromatic excimer laser. Forty-four patches were treated,
while 44 patches on the opposite side in the same patients were
kept as controls. The patches were divided in two groups MEL 1
group where the treatments were given once weekly and MEL 2
group where treatments were given twice weekly. A total of 24
sessions were delivered with dose elevations by 100 mJ/cm 2 every
session. Assessment was done by visual analogue scores at the end
of the treatments. Patient satisfaction scores were also noted.
Results: MEL was found to be effective modality of the treatment
as 61.36% of the patches achieved > 50% repigmentation in 24
sessions. The repigmentation could be even more if the treatment
in continued further. There was no difference found in average
visual analogue scores in MEL 1 and MEL 2 groups. Patient
satisfaction was; however, higher for the MEL 2 group than MEL
1 group. Both twice weekly and once weekly regimens were well
tolerated with no difference between them.
Conclusion: Our study shows effectiveness of the monochromatic
excimer light in the treatment of vitiligo and it can be considered a
treatment option for the treatment. Also there was no difference
found in the repigmentation achieved by once weekly or twice
weekly regimens.
#108
USE OF COMBINATION LASERS FOR MORE
EFFECTIVE HAIR REMOVAL
Dina Yaghmai, Abnoeal Bakus, Jerome Garden
Northwestern Hospital, Chicago, IL
For many patients single laser approaches to hair removal have
not been fully effective. Use of a given laser can result in the
reduction of only hair shafts with a specific diameter or in the
miniaturization of the hair shaft, resulting in the persistence of
many hairs. The objective of this study was to evaluate the
effectiveness of sequential treatments with two different lasers for
more improved hair removal. Fifteen subjects with skin types I–
V, pigmented fine and coarse caliber hair, underwent a series of
laser treatments at monthly intervals. Each of the subjects were
treated with either the combination of 810 nm diode and 1,064 nm
Q-switched Nd:YAG or combination of the long pulsed 1,064 nm
and the Q-switched Nd:YAG lasers. Sequential treatments with
two lasers were done during the same treatments session.
Subjects on average underwent 5–7 treatments with the use of
the combination lasers. This resulted in an increase in hair
reduction compared to previous methods. The treatments were
well tolerated. Combination lasers are a more effective treatment
option for laser hair removal, relative to the standard single laser
treatment approach.
#109
CLINICAL EVALUATION OF A 800 NM
LONG-PULSED DIODE LASER DEVICE WITH A
LARGE SPOT SIZE AND VACUUM-ASSISTED
SUCTION FOR HAIR REMOVAL
Omar Ibrahimi, Suzanne Kilmer