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Presidential Greeting - American Society for Laser Medicine and ...

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48 <strong>American</strong> <strong>Society</strong> <strong>for</strong> <strong>Laser</strong> <strong>Medicine</strong> <strong>and</strong> Surgery Abstracts<br />

#161<br />

that present at our <strong>Laser</strong> Rehabilitation Clinics on a daily basis.<br />

The various categories of cervical spine pathologies, are reviewed<br />

on the basis of age, gender distribution, number of treatments <strong>and</strong><br />

overall improvement percentages.<br />

Results: Of the 101 patients included in this study, 49%<br />

presented with degenerative osteoarthritis, 22% with repetitive<br />

stress injuries, 18% with sports injuries <strong>and</strong> 12% with trauma. On<br />

average 10 treatments of 30–45 minutes in duration were<br />

administered <strong>for</strong> the individual patient, resulting in a significant<br />

improvement rate averaging 94.5%.<br />

Conclusion: <strong>Laser</strong> therapy confers benefit at both the cellular<br />

<strong>and</strong> systemic levels, activating a variety of mechanisms<br />

including DNA synthesis, improved microcirculation <strong>and</strong> both an<br />

analgesic <strong>and</strong> anti-inflammatory effect. With a combination of<br />

red <strong>and</strong> infrared LED’s <strong>and</strong> laser diodes as a light source<br />

treatment was effective <strong>for</strong> an extensive variety of cervical spine<br />

problems.<br />

#160<br />

INNOVATIVE METHOD TO IMPROVE EFFICACY<br />

AND TOLERABILITY OF PDT TREATMENTS<br />

Carl Thornfeldt, CT Derm<br />

Fruitl<strong>and</strong>, ID<br />

Background: To produce a photodynamic therapy (PDT)<br />

regimen with improved efficacy <strong>and</strong> patient tolerability while<br />

allowing faster administration time. This regimen consists of:<br />

(1) Microdermabrasion.<br />

(2) Infrared LED at 830 nm <strong>for</strong> 20 minutes to inhibit neurogenic<br />

inflammation <strong>and</strong> stimulate deep dermal collagen, elastin <strong>and</strong><br />

glycosaminoglycan synthesis.<br />

(3) 540 nm green light laser.<br />

(4) 570 nm yellow light laser.<br />

(5) 628 nm red LED <strong>for</strong> 20 minutes.<br />

Study: Ten Caucasian panelists participated in an open label<br />

unblinded clinical trial comparing results to baseline with two<br />

PDT treatments each 4–8 weeks apart. Efficacy was graded four<br />

weeks after second treatment. Post-op care required applying a<br />

gel mask containing meadowfoam extract to provide DHA <strong>and</strong><br />

fatty acids <strong>for</strong> acetylcholine synthesis <strong>and</strong> anti-inflammatory<br />

effect. Home care consisted of applying a barrier repairing cream<br />

that is twice as effective as 100% petrolatum in repairing barrier<br />

function every 2–4 hours while awake <strong>for</strong> the next 4 days. All<br />

panelists stayed indoors <strong>for</strong> 24 hours after the treatment.<br />

Tolerability was subjectively assessed by panelists retrospectively<br />

comparing pain, tenderness, itching <strong>and</strong> soreness to previous<br />

chemical peels <strong>and</strong> red <strong>and</strong>/or blue light LED-activated PDT<br />

treatments. Fine lines, shallow wrinkles, sallowness <strong>and</strong><br />

roughness were measured on a 5-point scale by a board certified<br />

dermatologist 4 weeks after the second treatment. Panelists<br />

rated visible improvements <strong>and</strong> treatment symptoms on a 4-point<br />

scale.<br />

Results: All 10 panelists experienced at least a 1 point<br />

improvement (20%) in all parameters. Six patients experienced 3<br />

point improvement (60%) in all parameters. Subjectively all<br />

patients reported good to marked (50–75%) improvement. All<br />

patients stated the test regimen was markedly (75%) more<br />

tolerable.<br />

Conclusion: This unique regimen utilizes longer wavelength<br />

light to maximally activate the smaller aminolevulinic acid peaks,<br />

but not blue light peaks, yet is more effective <strong>and</strong> better tolerated<br />

due to deeper penetration.<br />

A PROSPECTIVE SPLIT-FACE DOUBLE-BLIND<br />

RANDOMIZED PLACEBO-CONTROLLED TRIAL<br />

TO ASSESS THE EFFICACY OF LIGHT-EMITTING<br />

DIODE POSTFRACTIONAL ABLATIVE LASER FOR<br />

SKIN REJUVENATION<br />

Valeria Campos, Juliana Jordao, Tatiana Cordero<br />

Clinica Valeria Campos, Jundiai, Brazil; Clinica Valeria Campos,<br />

Curitiba, Brazil; Clinica Valeria Campos, Campinas, Brazil<br />

Background: Light-emitting diodes (LEDs) are considered to be<br />

effective to stimulate fibroblast activity <strong>and</strong> hasten wound<br />

healing. We investigated the clinical efficacy of LED phototherapy<br />

on wound healing <strong>and</strong> <strong>for</strong> improvement of discom<strong>for</strong>t<br />

postfractional ablative laser.<br />

Objective: To determine whether LED treatment immediately<br />

after fractional laser skin resurfacing affects the severity <strong>and</strong><br />

duration of postoperative pain, erythema <strong>and</strong> wound healing.<br />

Study: Twenty patients received treatment with a LED array<br />

(Multiwaves, Industra, Brazil) to r<strong>and</strong>omly selected facial halves<br />

immediately after full-face fractional laser skin resurfacing with<br />

2,940 nm erbium laser (Etherea, Industra, Brazil) <strong>and</strong> 1 week<br />

after the laser treatment. The LED treatments were daily<br />

alternating wavelengths of 635 nm (red) with 940 nm (infrared)<br />

with fluences of 19.78 J/cm 2 or 11 mW/cm 2 <strong>and</strong> 9 J/cm 2 or 5 mW/<br />

cm 2 respectively, 20 minutes of light exposure. All laser<br />

procedures were per<strong>for</strong>med by a single operator. Clinical<br />

improvement was evaluated by participants <strong>and</strong> two blinded<br />

physicians by observing the comparative photographs. The rate of<br />

re-epithelialization, duration of pain, erythema, <strong>and</strong> presence of<br />

complications were recorded immediately after the procedure <strong>and</strong><br />

1 hour, 24 hour, 2, 3, 4, 5, 7, 30 days post-treatment.<br />

Results: The LED-treated facial halves were less painful in half<br />

of the patients after the first LED session. The average time to reepithelialization<br />

was 3 days in the LED-treated facial halves <strong>and</strong> 4<br />

days in the LED untreated facial halves.<br />

Conclusion: We believe that the LED after fractional ablative<br />

laser skin resurfacing will greatly enhance the natural wound<br />

healing process, <strong>and</strong> more quickly return the patient to a<br />

pretreatment level of activity.<br />

#162<br />

SAFETY AND EFFICACY OF FOOTLASER<br />

TREATMENT OF ONYCHOMYCOSIS IN PRIVATE<br />

PRACTICE<br />

Michael Uro, Laura Uro, Michael Abrahams,<br />

Martine Abrahams, Robert Grzywacz<br />

Foot Doctor <strong>Laser</strong> Center, Sacramento, CA;<br />

The London Nail <strong>Laser</strong> Clinic, London, Engl<strong>and</strong>; Las Vagas, NV<br />

Background: The aim of this study was to evaluate in a private<br />

practice the effectiveness of a single treatment with the PinPointe<br />

Foot<strong>Laser</strong> <strong>for</strong> onychomycosis.<br />

Study: One hundred <strong>and</strong> ninety-seven patients (321 great toes)<br />

from three private practices with clinical evidence of fungal nails<br />

received a single treatment of either one-pass or two-passes of the<br />

laser energy over all ten toe nails. Pre-treatment <strong>and</strong> follow-up<br />

post-treatment photographs of the hallux were digitized <strong>and</strong><br />

computer-analysed to evaluate safety <strong>and</strong> determine efficacy <strong>and</strong><br />

the change in percent clear nail out to 12 months.<br />

Results: The 2-pass treatment showed a greater treatment effect<br />

than the 1-pass treatment (11.2% vs. 4.4% increase in clear nail at<br />

6-months, respectively). Efficacy, percent of patients who showed

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