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Presidential Greeting - American Society for Laser Medicine and ...

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Conclusion: This new total combination therapy provides a<br />

promising treatment option <strong>for</strong> acne scars, <strong>and</strong> decreases side<br />

effects more than classic laser skin resurfacing or sequential<br />

combination therapy.<br />

#228<br />

CLINICAL STUDY TO EVALUATE THE EFFICACY<br />

AND SAFETY OF FRACTIONAL<br />

RADIOFREQUENCY SYSTEM<br />

Taewoo Noh, Tae Woo Noh, Yoo Seok Kang,<br />

Un Ha Lee, Hyun Su Park, Sang Jai Jang,<br />

Bang Soon Kim<br />

Sanggye Paik Hospital; S & U Clinic, Seoul, Korea<br />

Background: Fractional lasers achieved good results of<br />

rejuvenation with lesser epidermal damages. The eMatrix<br />

(Syneron Medical Ltd, Yokneam, Israel) is capable of delivering<br />

ablative radiofrequency (RF) energy to the skin in a nonhomogeneous<br />

fractional manner via an array of multi-electrode<br />

pins. The electrode pins lead to ablation of the skin directly <strong>and</strong> bipolar<br />

RF make the inverse cone shape of heating zone below the<br />

every electrode, leaving intact or slightly affected zones in<br />

between the targeted areas. The key differences between eMatrix<br />

<strong>and</strong> other fractional lasers are that there is very little epidermal<br />

disruption (5%) with relatively wider, deep dermal heating.<br />

Study: We conducted clinical study to assess the clinical efficacy<br />

<strong>and</strong> safety in 16 Korean patients. As the purpose of this study was<br />

also to find the optimal parameters <strong>for</strong> better outcome, different<br />

parameter (A mode vs. C mode) was assigned r<strong>and</strong>omly to split<br />

faces of 16 patients. Ten patients were treated r<strong>and</strong>omly with A or<br />

C mode in one cheek <strong>and</strong> with C or A mode in the other cheek,<br />

respectively, with 3–5 sessions of 3- to 4-week interval. The other<br />

six patients were treated in only one cheek with five sessions <strong>and</strong><br />

after then were treated in the other untreated cheek with<br />

different parameter. Clinical evaluations <strong>for</strong> the improvement<br />

<strong>and</strong> possible side effects were conducted every session, 8 weeks<br />

<strong>and</strong> up to 7 months after the last treatment.<br />

Results: All 16 patients showed improvement in skin brightness,<br />

skin tightness <strong>and</strong> wrinkles. Ten <strong>and</strong> six of patients had > 75%<br />

<strong>and</strong> 51–75% improvement, respectively. Typical initial response<br />

to treatment was mild to moderate erythema <strong>and</strong> edema which<br />

resolved within usually 1–5 days depending on applied energy.<br />

There was no postinflammatory hyperpigmentation developed.<br />

Conclusion: Fractional bipolar RF device, the eMatrix is<br />

effective <strong>and</strong> safe treatment <strong>for</strong> skin rejuvenation in Korean<br />

patients.<br />

#229<br />

<strong>American</strong> <strong>Society</strong> <strong>for</strong> <strong>Laser</strong> <strong>Medicine</strong> <strong>and</strong> Surgery Abstracts 67<br />

EFFECTIVE SCAR TREATMENT USING A<br />

FRACTIONAL 1,440 OR 1,540 NM LASER<br />

EQUIPPED WITH A POINT-ARRAY<br />

COMPRESSION OPTIC<br />

Arielle Kauvar, David Vasily, Christine Dierickx<br />

New York <strong>Laser</strong> & Skin Care, New York, NY; Aesthetica Cosmetic<br />

& <strong>Laser</strong> Center, Bethlehem, PA; Skin <strong>and</strong> <strong>Laser</strong> Center, Boom,<br />

Belgium<br />

Background: Treatment of scars appears to require remodeling<br />

of the abnormal dermal architecture, which often exceeds 1 mm in<br />

depth. Previous studies have shown that a fractional point-array<br />

compression optic (PCA) used with either 1,440 or 1,540 nm lasers<br />

can increase microbeam (mB) penetration <strong>and</strong> minimize<br />

epidermal disruption. This study observed the effects of this PCA<br />

optic with 1,440 or 1,540 nm lasers on scars.<br />

Study: This was an observational study of over 100 subjects with<br />

a wide variety of scars, including hypertrophic <strong>and</strong> keloidal, burn,<br />

traumatic, surgical, acne <strong>and</strong> hyperpigmented scars. Following<br />

application of a topical anesthetic, a 1,440 or 1,540 nm laser with a<br />

14 by 14 mm array PCA (XD TM , Palomar Medical Technologies,<br />

Inc.) delivered 49 mB with 2 mm pitch. Pulses were delivered with<br />

50% overlap in the vertical <strong>and</strong> horizontal direction or using a<br />

novel approach <strong>for</strong> a surface coverage of approximately 30–40%.<br />

Treatments occurred at 4- to 6-week intervals, <strong>and</strong> hypertrophic<br />

scars were treated adjuvantly with a topical corticosteroid.<br />

Results: Scar height, thickness, color <strong>and</strong> pliability improved at<br />

least 50% in 24 of the 26 subjects who have already completed<br />

follow-ups. In two subjects with erythematous, symptomatic<br />

keloidal scars, treatment had no effect <strong>and</strong> was discontinued after<br />

two sessions. The number of treatment sessions ranged from one<br />

to four. Post-treatment erythema <strong>and</strong> pinpoint micro-crusts<br />

persisted <strong>for</strong> 1 to 2 weeks. Two phototype IV subjects treated with<br />

the 1,440 nm laser experienced transient hyperpigmentation, but<br />

there were no other adverse effects. Studies with both these lasers<br />

are ongoing <strong>and</strong> additional safety <strong>and</strong> efficacy data will be<br />

presented.<br />

Conclusion: A 1,440 or 1,540 nm laser with a fractional pointarray<br />

compression tip significantly improved the appearance of a<br />

wide variety of scar types, with minimal anesthesia requirements<br />

<strong>and</strong> recovery times following high coverage treatment with high<br />

energies.<br />

#230<br />

CLINICAL EVALUATION OF A NON-INVASIVE<br />

CRYOLIPOLYSIS FOR THE TREATMENT OF<br />

SUBCUTANEOUS FAT REMOVAL IN KOREAN<br />

PATIENTS<br />

Hyunjoo Kim, Donghye Suh, Jiyoung Park,<br />

Jiho Rhue, Sangjun Lee, Kyeyoung Song,<br />

Minkyung Shin, Chulsu Ok<br />

Anacli Dermatologic Clinic, Sungnam, South Korea; Anacli<br />

Dermatologic Clinic; JungAng University; KyungHee University;<br />

Mediscope Clinic, Seoul, South Korea<br />

Background: Fat cells are more cold-sensitive than other cells,<br />

including epidermis. Cryolipolysis is a new method of noninvasive<br />

fat layer reduction, which has been shown to significantly<br />

reduce fat layer thickness without damage to the skin or other<br />

surrounding tissues. To evaluate the safety <strong>and</strong> efficacy profile of<br />

cryolipolysis <strong>for</strong> fat layer reduction of the abdomens or flanks in<br />

Koreans.<br />

Study: Twenty-five subjects with fat bulges on their abdomens or<br />

flanks (‘‘love h<strong>and</strong>les’’) were treated unilaterally or bilaterally<br />

with a non-invasive cooling device (Zeltiq Aesthetics, Pleasanton,<br />

CA). The results were evaluated based on clinical photos be<strong>for</strong>e<br />

<strong>and</strong> after session, physician assessments. Computed tomography<br />

<strong>and</strong> microscopic pathology were being per<strong>for</strong>med at pretreatment<br />

<strong>and</strong> posttreatment in some patients.<br />

Results: Photographic, physician assessment showed<br />

cryolipolysis results in a visible contour change in 20 subjects 6<br />

months later. Five subjects were developed petechia on their skin<br />

after treatment. This was almost completely disappeared after 1<br />

week.<br />

Conclusion: Cryolipolysis is a very low risk, no downtime<br />

procedure that produces consistent observations of modest,<br />

gradual fat layer reductions in properly selected patient.

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