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Milk production (kg)<br />

CHAPTER 4.1<br />

was only lowered in MD+ (P < 0.0001). Lactations <strong>of</strong> H cows show a faster rise in<br />

production (lower ramp) <strong>and</strong> faster decline (lower persistence, higher decay, P < 0.0001)<br />

in comparison with lactation curves <strong>of</strong> cows with one (MD) or multiple (MD+) metabolic<br />

problems. The scale <strong>of</strong> production is only diminished in MD+ cows compared to H <strong>and</strong><br />

MD. The significant interaction term for both ramp <strong>and</strong> scale between MD <strong>and</strong> parity<br />

revealed a more severe impact <strong>of</strong> MD on the ramp in older cows (Parity >2) next to a<br />

remarkably decreased scale in MD+ second parity cows compared to H. The lactation<br />

curves corresponding to the parameter values in Table 3 are separately shown for parity<br />

1 (Figure 2), parity 2 (Figure 3) <strong>and</strong> parity 2+ (Figure 4). As a result <strong>of</strong> the change in the<br />

lactation curve, the TPEAK increased (P < 0.0001) between H, MD <strong>and</strong> MD+ while both<br />

the MPEAK (P < 0.0001) <strong>and</strong> M60 (P < 0.0001) were only decreased when cows<br />

encountered a complicated MD+ especially in >1 parity cows. The overall M305 was<br />

equal in H <strong>and</strong> MD cows but was lowered in MD+ (P = 0.029) especially in second-parity<br />

cows (P = 0.037 for the interaction term).<br />

50<br />

45<br />

40<br />

35<br />

30<br />

25<br />

20<br />

15<br />

10<br />

5<br />

0<br />

0 50 100 150 200 250 300<br />

DIM<br />

Figure 2. The effect <strong>of</strong> metabolic problems on lactation curve shape in first<br />

lactation cows: cows that encountered no metabolic problem during the transition<br />

period (green line), cows that encountered 1 metabolic problem during the<br />

transition period (orange line) <strong>and</strong> cows that encountered more than 1 metabolic<br />

problem during the transition period (red line).<br />

76

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