Немецкий медицинский журнал Немецкий медицинский журнал
Немецкий медицинский журнал Немецкий медицинский журнал
Немецкий медицинский журнал Немецкий медицинский журнал
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Hilar Cholangiocarcinoma<br />
THE JOURNAL OF MEDICINE FOR THE WORLDWIDE MED COMMUNITY<br />
холангиокарцинома<br />
Table 3c: Schematic overview of<br />
the “Essen Treatment Protocol” for<br />
patients with non-resectable tumours<br />
or metastases<br />
Schematic Overview of the “Essen Treatment Protocol” for Patients<br />
with Non-Resectable Tumours or Metastases<br />
All eligible and consenting patients with central<br />
cholangiocarcinoma<br />
5. Histological diagnosis using ERCP;<br />
Alternatively, proof provided by high tumour markers<br />
6. Excluding distant metastases in PET-CT<br />
Таблица 3c: Схематический обзор «Протокол<br />
лечения ESSEN» для пациентов<br />
с неоперабельными опухолями или<br />
метастазами<br />
Discussing the<br />
individual case in an<br />
oncological / surgical<br />
conference<br />
Exploratory laparotomy for locally non-resectable tumours<br />
and/or distant metastases<br />
Literature<br />
1. Khan SA, Heimbach JK, Rosen CB,<br />
Haddock MG, et al. (2005) Cholangiocarcinoma.<br />
Lancet 366:1303-14.<br />
2. Lang H, Kaiser GM, Zöpf T, Sotiropoulos<br />
GC, Frilling A, Malago M, et al.<br />
(2006) Zentrale Gallengangskarzinome.<br />
Chirurg 77:325-34.<br />
3. Kaiser GM, Frühauf NR, Lang H, et<br />
al. (2008) Impact of intraoperative<br />
Radiotherapy (IORT) on survival of<br />
patients with unresectable hilar cholangiocarcinoma.<br />
Hepatogastroenterology<br />
55:1951-4.<br />
4. Rosen CB, Heimbach JK, Gores<br />
GJ. (2010) Liver transplantation for<br />
cholangiocarcinoma. Transplant Int<br />
23:692-697.<br />
5. Kaiser GM, Sotiropoulos GC, Jauch<br />
KW, et al. (2008) Liver transplantation<br />
for hilar cholangiocarcinoma: a German<br />
survey. Transplant Proc 40:3191-3.<br />
6. Kaiser GM, Sotiropoulos GC, Lang H,<br />
et al. (2010) Surgical treatment of hilar<br />
cholangiocarcinoma: Liver resection<br />
vs. transplantation. Hepatogastroenterology<br />
57: 1337-40<br />
7. Valle J, Wasan H, et al. (2010). Cisplatin<br />
plus gemcitabine versus gemcitabine<br />
alone for biliary tract cancer. N<br />
Engl J Med 362: 1273-1281.<br />
8. Wiedmann MW, Mössner J (2010).<br />
Molecular targeted therapy of biliary<br />
tract cancer – results of the first<br />
clinical studies. Curr Drug Targets 11:<br />
834-850.<br />
9. Li J, Kuehl H, Grabellus F, et al. (2008).<br />
Preoperative assessment of hilar<br />
cholangiocarcinoma by dual-modality<br />
PET/CT. J Surg Oncol 98:438.<br />
10. Romaneehsen B, Otto G, et al. (2004).<br />
[Diagnostic imaging of hilar cholangiocarcinoma:<br />
preoperative evaluation<br />
of ERC, MRC and PTC in comparison<br />
with histopathology]. Röfo 176: 1750-<br />
8.<br />
11. Juntermanns B, Kaiser GM, Reis H,<br />
Saner FH, Radunz S, Vernadakis S,<br />
Kuehl H, Paul A, Treckmann J. Klatskin-<br />
Mimicking lesions: Still a diagnostical<br />
and therapeutical dilemma. (2011).<br />
Hepato-Gastroenterology, in press<br />
12. Tannapfel A, Wittekind C (2004)<br />
[Gallbladder and bile duct carcinoma.<br />
Biology and pathology]. Internist 45:<br />
33-41.<br />
PD Dr. G.M. Kaiser (MD)<br />
Dr. B. Juntermanns (MD)<br />
Prof. Dr. G. Sotiropoulus (MD)<br />
Dr. M. Heuer (MD)<br />
Prof. Dr. A. Paul (MD)<br />
Palliative care including<br />
chemotherapy / radio chemotherapy /<br />
photodynamic therapy<br />
Discussing the<br />
individual case in an<br />
oncological / surgical<br />
conference<br />
Department of General, Visceral<br />
and Transplantation Surgery<br />
West German Tumour Centre<br />
University Hospital of Essen<br />
gernot.kaiser@uk-essen.de<br />
65
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