Scabies mites are very small, about 0.2 to 0.4 mm. Both sexes burrow in the horny layerof the skin, but only the female makes permanent winding burrows parallel to the skinsurface. The female lays a few eggs in the burrows. The six-legged larvae that hatchfrom the eggs leave the burrow and move to the hair follicles. Two nymphal stages thatprecede the adult are also found in the hair follicles. The entire life cycle takes 10 to 14days. Scabies is transmitted from person to person only by close prolonged personalcontact. Transmission is common in dormitories, barracks and medical facilities. Mitesdie rapidly away from the human body.Most mite burrows occur in the interdigital and elbow skin, but skin of the scrotum,breasts, knees and buttocks is also affected. The face and scalp are rarely involved. Innewly infested persons, a period of 3 to 4 weeks usually elapses before sensitization tomites and mite excretions develops. Itching is not experienced during this period, andinfestations may progress extensively before being noticed. However, fewer than 20mites are enough to produce intense itching, particularly at night. The burrows oftenbecome secondarily infected with bacteria. In infested persons, an extensive rash cancover areas where there are no mites. In immunocompromised individuals, who do notrespond to infestation by itching and scratching, mites can reach very high populationsand produce a scaly, crusted skin known as Norwegian scabies.Scabies is the most important disease caused by mite infestation. It is cosmopolitan andcommon in the <strong>Middle</strong> <strong>East</strong>. Persons of all ages are affected. In developing countries,infestation is highest in poor communities and in children. Scabies is not a reportabledisease in most countries; thus, estimated rates of infestation are usually inaccurate.Scabies is usually only reported when large outbreaks occur. Increases in the incidence ofscabies appear to occur in 15 to 20 year cycles that are related to fluctuating levels ofimmunity to S. scabiei. In the Israel Defense Force, compulsory reporting of scabies hasbeen required since 1968. There was a 13-year period of quiescence from theimplementation of reporting until 1981. This period was followed by an epidemic of 15years, peaking in 1985 and 1986, and a return to the baseline rates of the quiescent periodby 1996.2. Araneae (spiders). More than 34,000 species of spiders have been describedworldwide. All spiders, with the exception of the family Uloboridae, are venomous anduse their venom to immobilize or kill prey. Most spiders are harmless because theirchelicerae cannot penetrate human skin, or they have venom of low toxicity to humans.Those that can bite humans are rarely seen or recovered for identification, so physiciansneed to be able to recognize signs and symptoms of common venomous spider bites inorder to administer appropriate therapy. In the <strong>Middle</strong> <strong>East</strong> the widow spiders,Lactrodectus spp., and the violin (brown recluse) spiders, Loxosceles spp., are responsiblefor significant local or systemic effects from envenomization.The adult brown recluse or fiddleback spider (Loxosceles spp.) is medium-sized with a 2to 4 cm legspan. Distinguishing characteristics include six eyes arranged in a semicircleof three pairs on the top of the head and a violin-shaped marking extending from the areaof the eyes to the beginning of the abdomen. The violin-shaped marking may not alwaysbe apparent. The brown recluse is nocturnal in its feeding habits and is most frequently133
found in cellars of buildings, cardboard boxes, storage areas, the folds of clothing, andalso outdoors under rocks and rubble. Members of the genus are shy, nonaggressive, andbite only defensively. They may live as long as two years.The brown recluse bite is usually localized but may produce considerable necrosisresulting in significant scarring. Research on the venom has indicated that its action isnecrotic and hemolytic but not neurologic. The bite is usually painless until 3 to 8 hourslater, when it may become red, swollen, and tender. Later a black scab may develop, andeventually an area around the site may decay and slough away, producing a large ulcerfrom 1 to 25 cm in diameter. Healing can require months. Death is rare but has beenrecorded as a result of systemic effects. Treatment of Loxosceles bites is controversialbecause few controlled studies have been conducted, and the severity of the bite isvariable. A specific antivenin has shown success with patients prior to development of thenecrotic lesion, but currently it is not widely available.Several species of widow spiders occur in the <strong>Middle</strong> <strong>East</strong>, but Latrodectus mactansis the one most associated with the name "black widow spider." It is also referred to asthe hourglass, shoe button, or po-ko-moo spider. Considerable variation in coloration andmarkings exists between species and between immature and adult spiders. Widow spidersare found in various habitats in the wild, especially in protected places such as crawlspaces under buildings, holes in dirt embankments, piles of rocks, boards, bricks orfirewood. Indoors, they prefer dark areas behind or underneath appliances, in deep closetsand cabinets. They commonly infest outdoor privies, and these should be routinelyinspected by preventive medicine personnel. Widow spiders spin a crude web and usuallywill not bite unless provoked.Latrodectus spp. inject a potent neurotoxin when biting. The bite itself is mild and mostpatients don't remember being bitten. Significant envenomization results in severesystemic symptoms, including painful muscle spasms, a rigid board-like abdomen, andtightness in the chest. Mortality rates from untreated bites have been estimated at 1 to 5%.Most envenomizations respond quickly to sustained intravenous calcium gluconate.Antivenins are commercially available and very effective.3. Ceratopogonidae (biting midges, no-see-ums, punkies). The Ceratopogonidae are alarge family containing nearly 4,000 species. These extremely small flies can easily passthrough window screens and standard mosquito netting. Their small size is responsiblefor the moniker "no-see-ums." Many species in this group attack and suck fluids fromother insects. Most species that suck vertebrate blood belong to the genera Culicoides(1,000 species) or Leptoconops (about 80 species). In the <strong>Middle</strong> <strong>East</strong> these insects do nottransmit human diseases, but they do serve as vectors for several diseases of veterinaryimportance. Many species of Ceratopogonidae are widespread in the region, but little isknown about their biology. Most <strong>Middle</strong> <strong>East</strong>ern species of Culicoides are zoophilic.Leptoconops are more likely to be a major nuisance to man. Blood-sucking speciespredominately feed and rest outdoors, entering houses in much smaller numbers. Onlyfemales suck blood. Leptoconops are active during the day; Culicoides may be eitherdiurnal or nocturnal. Diurnal species of both genera prefer early morning and lateafternoon periods. Despite their small size, they often cause local reactions severe enoughto render a military unit operationally ineffective. In sensitive people bites may blister,134
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1. Table of ContentsI. Preface.....
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IX.Selected ReferencesA. Military P
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and spills have polluted sea- and l
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Sand fly fever is the most widespre
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VENOMOUS ANIMALSThere are 31 specie
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Middle East11
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leptospires, various bacteria and i
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Bandar Abbas (elevation 10 m)Mean D
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a wide variety of human pathogens.
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The Jordan Valley area is part of t
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still numerous sites where waste di
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highlands (445 m elevation) are sim
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ocky central plateau, the Nejd, whi
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MONTH J F M A M J J A S O N DMaximu
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known as the Liwa, form an arc alon
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___________________________________
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Table 1. Drug-Resistant Falciparum
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Saudi Arabia: Malaria occurs in the
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General Bionomics. Female anophelin
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host with the body nearly perpendic
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crevices, leaf litter, or moist tre
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All dengue serotypes are now endemi
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period immediately following it (19
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Military Impact and Historical Pers
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Appendix B.2. Vector Ecology Profil
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B.2. Ticks continuedSpecies Geograp
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In recent years, synthetic pyrethro
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Published Reports of Insecticide Re
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Turkey.Calgar, S.S. 1991. An invest
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Appendix ESelected List of Identifi
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MammaliaHarrison, D.L. and P.J.J. B
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Appendix F: Personal Protective Mea
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Appendix GBioscience and State Depa
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8. Kuwait9. Lebanon10. Oman11. Qata
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Appendix H: Glossaryacaricide - a c
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zoonosis - An infectious disease of
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flies.11. Information on ticks and
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APPENDIX J METRIC CONVERSION TABLEM